Search results for "psa"
showing 10 items of 286 documents
Nuclear and chloroplast DNA variation in Cephalaria squamiflora (Dipsacaceae), a disjunct Mediterranean species
2009
Cephalaria squamiflora is a chamaephyte restricted to rupicolous habitats in islands of the Western (Balearic Islands, Sardinia) and Eastern Mediterranean (Crete and few Aegean islands). Four narrowly distributed races (subspp. squamiflora, mediterranea, ebusitana, balearica) have been described to encompass the morphological variation within the species. We have used nuclear ribosomal ITS and cpDNA sequences to assess how the patterns of molecular differentiation are related to taxonomic and geographic boundaries. Extensive intragenomic ITS variation was detected in samples from all territories, the average sequence divergence among cloned ribotypes was 1.339%. The parsimony network of clo…
What do leaf anatomy and micromorphology tell us about the psammophilous Pancratium maritimum (Amaryllidaceae) in response to sand dune conditions?
2015
Abstract The present study aimed at verifying the morphological variation in leaf traits among different populations of Pancratium maritimum (sea daffodil) and the correlation between leaf diversity and climate conditions at different sites. Eleven populations of P. maritimum from Mediterranean coastal sand dunes were investigated with respect to leaf surface micro-morphology, leaf anatomy, and vascular pattern. Morphometric analysis was based on 29 quantitative foliar parameters. One-way analysis of variance (ANOVA), principal component analysis (PCA), discriminant function analysis (DFA), and clustering by Ward’s method were used for the statistical evaluation. Results revealed a rather u…
NAIRU modelis Latvijas ekonomikai
2019
Darba galvenais mērķis ir aprēķināt NAIRU līkni Latvijā ar ikmēneša datiem laika posmā no 2005. gada līdz 2018.gadam, izmantojot Kalmana filtru. Teorētiskajā daļā izklāstīts bezdarba iedalījums, Filipsa līknes apraksts un matemātiskais formulējums, kā arī dažādas inflācijas prognozēšanas metodes un dabiskā bezdarba modeļu evolūcija no 20. gadsimta vidus līdz mūsdienām. Praktiskajā daļā vispirms aplūkotas dažādas laika rindas, kuras varētu būt iekļaujamas Latvijas NAIRU modelī, katrai modeļa komponentei piemeklējot 2 – 3 alternatīvus mainīgos. Turpinājumā, balstoties uz OECD metodoloģiju, iegūti un aprakstīti 2 labākie NAIRU modeļi un veikts to salīdzinājums ar līdzšinējo pētījumu rezultātie…
Saistība starp veģetācijas izplatību un augsnes apstākļiem neapsaimniekotajās lauksaimniecībā izmantojamās zemēs Līvānu apkārtnē
2017
Šajā pētījumā ir aprakstīti augsnes veidošanās ietekmējošie vides faktori, kā arī analizēta saistība starp veģetācijas izplatību un augsnes apstākļiem neapsaimniekotajās lauksaimniecībā izmantojamās zemēs Līvānu apkārtnē. Maģistra darba mērķis ir noskaidrot saistību starp veģetācijas izplatību un augsnes īpašībām neapsaimniekotajās lauksaimniecībā izmantojamās zemēs. Darbā ir aprakstītas likumsakarības starp augsnes fizikālajām un ķīmiskajām īpašībām un veģetācijas izplatību. Pētīta lauksaimniecības zemju dabiskā apmežošanās un tās iespējamā ietekme uz augsnes īpašībām. Pētījumā secināts, ka veģetācijas izplatību un sastāvu neapsaimniekotajās lauksaimniecībā izmantojamās zemēs ietekmē augsn…
Uzņēmuma SIA “Cander Nami” mārketinga komunikācijas analīze.
2021
Bakalaura darba izvēlētā tēma ir “ Uzņēmuma SIA “Cander Nami” mārketinga komunikācijas analīze”. Bakalaura darba mērķis ir novērtēt uzņēmuma SIA “Cander Nami” mārketinga komunikācijas, pamatojoties uz mārketinga teorētiskajiem aspektiem, darba autores novērojumiem un aptaujas rezultātiem, kā arī izstrādāt secinājumus un rast priekšlikumus uzņēmuma mārketinga komunikāciju pilnveidošanai. Darba mērķa sasniegšanai veicamie uzdevumi ir teorētisko aspektu analīze, esošo mārketinga komunikāciju analīze uzņēmumam SIA “Cander Nami”, pētījumu veikšana ar aptaujas, kā arī pētniecības metodes palīdzību, un secinājumu un priekšlikumu izstrādāšanu. Darbs sastāv no trīs nodaļām. Pirmajā nodaļā tiek apska…
Error calculation for the PSA quotient.
2008
Abstract Objective Prostate specific antigen (PSA) assays have significant measurement errors, but the error associated with the PSA quotient (free to total PSA) often remains unknown. Methods We used both Gaussian error calculation and measurement of imprecision to investigate the level of error associated with the PSA quotient. Results Surprisingly, we found that the error of the PSA quotient at low levels is markedly smaller than that of the total PSA value. Conclusions The PSA quotient should be calculated and considered as a clinically relevant value.
PSA Depletion Induces the Differentiation of Immature Neurons in the Piriform Cortex of Adult Mice
2021
Immature neurons are maintained in cortical regions of the adult mammalian brain. In rodents, many of these immature neurons can be identified in the piriform cortex based on their high expression of early neuronal markers, such as doublecortin (DCX) and the polysialylated form of the neural cell adhesion molecule (PSA-NCAM). This molecule plays critical roles in different neurodevelopmental events. Taking advantage of a DCX-CreERT2/Flox-EGFP reporter mice, we investigated the impact of targeted PSA enzymatic depletion in the piriform cortex on the fate of immature neurons. We report here that the removal of PSA accelerated the final development of immature neurons. This was revealed by a h…
Oral chemotherapy in hormone-refractory prostate carcinoma patients unwilling to be admitted to hospital.
2008
<i>Objectives:</i> To investigate the safety and efficacy in terms of PSA response of a low-dose oral combination of estramustine phosphate (EMP) and etoposide (VP16) in hormone- refractory prostate cancer (HRPC) patients. Well-tolerated outpatient chemotherapy regimens for patients unfit and/or unwilling to be admitted to hospital are needed. <i>Methods:</i> Fifty-six HRPC patients with metastatic disease (median age 75 years) were randomized between arm A (daily oral EMP 10 mg/kg, in 3 doses) and arm B (28-day cycle with low-dose EMP 3 mg/kg once daily plus VP16 25 mg/m<sup>2</sup> once daily on days 1 through 14). Baseline characteristics between the t…
PSA and second-line therapy of hormone refractory prostate carcinoma
2001
The aim of the present study was to correlate PSA response with subjective response (bone pain and performance status), in patients treated for hormone refractory carcinoma of the prostate. Twenty-four patients were introduced into the study. Median PSA was 198 ng/ml. Symptom score, performance status and PSA were monitored monthly for 3 months and then 3-monthly. Sixteen patients (66%) showed a PSA response (median value 10 ng/ml). In 8 patients (33%) PSA was 4 ng/ml. In conclusion, PSA response is not always related to subjective improvement and does not always implicate a beneficial effect of the therapy for the patient. Copyright © 2001 S. Karger AG, Basel.
Is free/total PSA predictive of pathological stage and Gleason score in patients with prostate cancer and serum PSAor=10 ng/ml?
2005
<i>Introduction:</i> To evaluate whether percent free prostate-specific antigen (%-fPSA) could be predictive of pathological stage and Gleason score in patients with prostate cancer (PCa) and serum PSA of 10 ng/ml or less. <i>Materials and Methods:</i> In 100 patients with total PSA≤10 ng/ml who underwent radical retropubic prostatectomy as primary treatment of PCa, %-fPSA levels in organ-confined vs. non-organ-confined PCa and in patients with Gleason score ≤/>7 were compared. <i>Results:</i> 32 patients had an organ-confined and 68 a locally advanced PCa. Median %-fPSA level was 15%; Gleasonscore was <7 in 49 patients, equal to 7 in 40 and >7 i…