Search results for "quantitative method"

showing 10 items of 170 documents

Structure Learning in Nested Effects Models

2007

Nested Effects Models (NEMs) are a class of graphical models introduced to analyze the results of gene perturbation screens. NEMs explore noisy subset relations between the high-dimensional outputs of phenotyping studies, e.g., the effects showing in gene expression profiles or as morphological features of the perturbed cell. In this paper we expand the statistical basis of NEMs in four directions. First, we derive a new formula for the likelihood function of a NEM, which generalizes previous results for binary data. Second, we prove model identifiability under mild assumptions. Third, we show that the new formulation of the likelihood allows efficiency in traversing model space. Fourth, we…

Statistics and ProbabilityTraverseComputer scienceMolecular Networks (q-bio.MN)Genes MHC Class IIPerturbation (astronomy)Genes InsectFeature selectionQuantitative Biology - Quantitative Methods03 medical and health sciences0302 clinical medicineGeneticsAnimalsheterocyclic compoundsQuantitative Biology - Molecular NetworksGraphical modelMolecular BiologyQuantitative Methods (q-bio.QM)Oligonucleotide Array Sequence Analysis030304 developmental biologyLikelihood Functions0303 health sciencesNanoelectromechanical systemsModels StatisticalModels GeneticGene Expression ProfilingGenomicsComputational MathematicsDrosophila melanogasterPhenotypeFOS: Biological sciencesBinary dataIdentifiabilityRNA InterferenceLikelihood functionAlgorithmAlgorithms030217 neurology & neurosurgery
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Infant mortality across species. A global probe of congenital abnormalities

2019

Infant mortality, by which we understand the postnatal stage during which mortality is declining, is a manifestation and embodiment of congenital abnormalities. Severe defects will translate into death occurring shortly after birth whereas slighter anomalies may contribute to death much later, possibly only in adult age. While for many species birth defects would be nearly impossible to identify, infant mortality provides a convenient global assessment. In the present paper we examine a broad range of species from mammals to fish to gastropods to insects. One of the objectives of our comparative analysis is to test a conjecture suggested by reliability engineering according to which the fre…

Statistics and Probability[PHYS]Physics [physics]Range (biology)Mortality rateFOS: Physical sciencesStatistical and Nonlinear PhysicsPostnatal StageBiology01 natural sciencesAdult ageQuantitative Biology - Quantitative MethodsInfant mortality010305 fluids & plasmas3. Good healthBiological Physics (physics.bio-ph)FOS: Biological sciences0103 physical sciencesFish <Actinopterygii>Physics - Biological Physics010306 general physicsQuantitative Methods (q-bio.QM)Demography
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Evidence of stochastic resonance in the mating behavior of Nezara viridula (L.)

2008

We investigate the role of the noise in the mating behavior between individuals of Nezara viridula (L.), by analyzing the temporal and spectral features of the non-pulsed type female calling song emitted by single individuals. We have measured the threshold level for the signal detection, by performing experiments with the calling signal at different intensities and analyzing the insect response by directionality tests performed on a group of male individuals. By using a sub-threshold signal and an acoustic Gaussian noise source, we have investigated the insect response for different levels of noise, finding behavioral activation for suitable noise intensities. In particular, the percentage…

Stochastic resonanceFOS: Physical sciencesNoise in biological systemQuantitative Biology - Quantitative MethodsSignalsymbols.namesakeDirectionalityDetection theoryPhysics - Biological PhysicsQuantitative Methods (q-bio.QM)Biophysical mechanisms of interactionPhysicsFluctuation phenomena random processes noise and Brownian motionbiologyNoise (signal processing)Noise in biological systems; Biophysical mechanisms of interaction; Fluctuation phenomena random processes noise and Brownian motionCondensed Matter Physicsbiology.organism_classificationSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Electronic Optical and Magnetic MaterialsBiological Physics (physics.bio-ph)Gaussian noiseNezara viridulaFOS: Biological sciencessymbolsThreshold modelBiological system
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Biproportional Method for Analysing Interindustry Dynamics: the case of France

1990

Two elements are being presented in this paper: (1) A new and original method for analysing matrix dynamics, called the synthetical biproportional projector method (SBP), which can be used to project input–output tables and compare one with another. (2) Some results for France for the important period 1970–85. The paper starts with the observation that no systematic study of the change in the French productive structure as displayed In the input–output tables (tableaux entries-sorties in France) has ever been made. This is unfortunate, since a complete series of data is now available concerning a key period of the French economic evolution including the petroleum crisis, European integratio…

Structure (mathematical logic)JEL : C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C67 - Input–Output ModelsEconomics and EconometricsEngineeringJEL: C - Mathematical and Quantitative Methods/C.C6 - Mathematical Methods • Programming Models • Mathematical and Simulation Modeling/C.C6.C67 - Input–Output ModelsOperations researchbusiness.industryJEL: L - Industrial Organization/L.L1 - Market Structure Firm Strategy and Market Performance/L.L1.L16 - Industrial Organization and Macroeconomics: Industrial Structure and Structural Change • Industrial Price IndicesJEL: D - Microeconomics/D.D5 - General Equilibrium and Disequilibrium/D.D5.D57 - Input–Output Tables and Analysis[SHS.ECO]Humanities and Social Sciences/Economics and FinanceDynamics (music)European integrationJEL : D - Microeconomics/D.D5 - General Equilibrium and Disequilibrium/D.D5.D57 - Input–Output Tables and Analysis[ SHS.ECO ] Humanities and Social Sciences/Economies and financesEvolutionary economicsJEL : L - Industrial Organization/L.L1 - Market Structure Firm Strategy and Market Performance/L.L1.L16 - Industrial Organization and Macroeconomics: Industrial Structure and Structural Change • Industrial Price Indicesbusiness[SHS.ECO] Humanities and Social Sciences/Economics and FinanceMathematical economicsComputingMilieux_MISCELLANEOUS
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A contribution to the mathematical modeling of immune-cancer competition

2018

Abstract This paper deals with the modeling of interactions between the immune system and cancer cells, in the framework of the mathematical kinetic theory for active particles. The work deepens a previous paper of Belloquid et al. that assumes spatial homogeneity and discrete values of the activity of cancer and immune cells. A number of simulations are made with the aim to investigate how the state of the various cell populations evolves in time depending on the choice of the free parameters.

T57-57.97Applied mathematics. Quantitative methodsApplied MathematicsCancer010103 numerical & computational mathematicsmedicine.disease01 natural sciencesIndustrial and Manufacturing EngineeringKinetic Theoryactive particlesevolution010101 applied mathematicsCompetition (economics)Immune systemmedicineCancer researchEconomics0101 mathematicsSettore MAT/07 - Fisica Matematica
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Inhomogeneous vortex tangles in counterflow superfluid turbulence: flow in convergent channels

2016

Abstract We investigate the evolution equation for the average vortex length per unit volume L of superfluid turbulence in inhomogeneous flows. Inhomogeneities in line density L andincounterflowvelocity V may contribute to vortex diffusion, vortex formation and vortex destruction. We explore two different families of contributions: those arising from asecondorder expansionofthe Vinenequationitself, andthose whichare notrelated to the original Vinen equation but must be stated by adding to it second-order terms obtained from dimensional analysis or other physical arguments.

T57-57.97Applied mathematics. Quantitative methodsTurbulenceApplied MathematicsQuantum turbulenceQuantum turbulence quantized vortices heat transfer inhomogeneous vortex tangle vortex diffusion.Quantized vorticesquantum turbulencevortex diffusion01 natural sciencesIndustrial and Manufacturing Engineering010305 fluids & plasmasVortexSuperfluidityClassical mechanicsCondensed Matter::Superconductivity0103 physical sciencesHeat transferheat transferinhomogeneous vortex tangle010306 general physicsSettore MAT/07 - Fisica Matematicaquantized vorticesCommunications in Applied and Industrial Mathematics
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Discontinuous Galerkin semi-Lagrangian method for Vlasov-Poisson

2011

We present a discontinuous Galerkin scheme for the numerical approximation of the one-dimensional periodic Vlasov-Poisson equation. The scheme is based on a Galerkin-characteristics method in which the distribution function is projected onto a space of discontinuous functions. We present comparisons with a semi-Lagrangian method to emphasize the good behavior of this scheme when applied to Vlasov-Poisson test cases. Une méthode de Galerkin discontinu est proposée pour l’approximation numérique de l’équation de Vlasov-Poisson 1D. L’approche est basée sur une méthode Galerkin-caractéristiques où la fonction de distribution est projetée sur un espace de fonctions discontinues. En particulier, …

T57-57.97Applied mathematics. Quantitative methods[SPI.PLASMA]Engineering Sciences [physics]/Plasmas010103 numerical & computational mathematicsSpace (mathematics)Poisson distribution01 natural sciences010101 applied mathematicssymbols.namesakeTest caseDistribution functionNumerical approximationDiscontinuous Galerkin methodScheme (mathematics)QA1-939symbolsApplied mathematics0101 mathematicsAlgorithmMathematicsLagrangian[MATH.MATH-NA]Mathematics [math]/Numerical Analysis [math.NA]Mathematics
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Parallel Computing for the study of the focusing Davey-Stewartson II equation in semiclassical limit

2012

The asymptotic description of the semiclassical limit of nonlinear Schrödinger equations is a major challenge with so far only scattered results in 1 + 1 dimensions. In this limit, solutions to the NLS equations can have zones of rapid modulated oscillations or blow up. We numerically study in this work the Davey-Stewartson system, a 2 + 1 dimensional nonlinear Schrödinger equation with a nonlocal term, by using parallel computing. This leads to the first results on the semiclassical limit for the Davey-Stewartson equations.

T57-57.97Work (thermodynamics)Applied mathematics. Quantitative methods010102 general mathematicsOne-dimensional spaceMathematics::Analysis of PDEsSemiclassical physics010103 numerical & computational mathematicsParallel computing01 natural sciencesSchrödinger equationsymbols.namesakeNonlinear systemNonlinear Sciences::Exactly Solvable and Integrable SystemsQA1-939symbolsLimit (mathematics)0101 mathematicsNonlinear Sciences::Pattern Formation and SolitonsNonlinear Schrödinger equationMathematicsMathematicsESAIM: Proceedings
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Graph-based exploration and clustering analysis of semantic spaces

2019

Abstract The goal of this study is to demonstrate how network science and graph theory tools and concepts can be effectively used for exploring and comparing semantic spaces of word embeddings and lexical databases. Specifically, we construct semantic networks based on word2vec representation of words, which is “learnt” from large text corpora (Google news, Amazon reviews), and “human built” word networks derived from the well-known lexical databases: WordNet and Moby Thesaurus. We compare “global” (e.g., degrees, distances, clustering coefficients) and “local” (e.g., most central nodes and community-type dense clusters) characteristics of considered networks. Our observations suggest that …

Text corpusSemantic spacesComputer Networks and CommunicationsComputer sciencegraph theory0211 other engineering and technologiesWordNetNetwork science02 engineering and technologysemanttinen webSemantic networkword2vec similarity networksWord2vec similarity networksClique relaxationscohesive clusters0202 electrical engineering electronic engineering information engineeringWord2vecCluster analysisThesaurus (information retrieval)021103 operations researchMultidisciplinaryInformation retrievalverkkoteorialcsh:T57-57.97Graph theorycliquesGraph theoryclique relaxationsComputational MathematicsCliqueslcsh:Applied mathematics. Quantitative methodssemantic spaces020201 artificial intelligence & image processingCohesive clusters
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Statistically validated networks in bipartite complex systems.

2011

Many complex systems present an intrinsic bipartite nature and are often described and modeled in terms of networks [1-5]. Examples include movies and actors [1, 2, 4], authors and scientific papers [6-9], email accounts and emails [10], plants and animals that pollinate them [11, 12]. Bipartite networks are often very heterogeneous in the number of relationships that the elements of one set establish with the elements of the other set. When one constructs a projected network with nodes from only one set, the system heterogeneity makes it very difficult to identify preferential links between the elements. Here we introduce an unsupervised method to statistically validate each link of the pr…

Theoretical computer scienceComputer sciencelcsh:MedicineNetwork theorySocial and Behavioral SciencesBioinformaticsQuantitative Biology - Quantitative MethodsSociologyProtein Interaction Mappinglcsh:ScienceQuantitative Methods (q-bio.QM)MultidisciplinarySystems BiologyApplied MathematicsPhysicsStatisticsComplex SystemsGenomicsLink (geometry)Social NetworksSpecialization (logic)Interdisciplinary PhysicsBipartite graphProbability distributionResearch ArticleNetwork analysisPhysics - Physics and SocietyComplex systemFOS: Physical sciencesPhysics and Society (physics.soc-ph)Type (model theory)BiologyModels BiologicalNetwork theory Statistical PhysicsStatistical MechanicsSet (abstract data type)Statistical MethodsBiologyStructure (mathematical logic)Statistical Physicslcsh:RComputational BiologyModels TheoreticalComparative GenomicsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)FOS: Biological sciencesNetwork theorylcsh:QNull hypothesisMathematicsPLoS ONE
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