Search results for "quantitative"

showing 10 items of 2409 documents

Investigation of the hemodynamic flow conditions and blood-induced stresses inside an abdominal aortic aneurysm by means of a SPH numerical model.

2019

The estimation of blood flow-induced loads occurring on the artery wall is affected by uncertainties hidden in the complex interaction of the pulsatile flow, the mechanical parameters of the artery, and the external support conditions. To circumvent these difficulties, a specific tool is developed by combining the aorta displacements measured by an electrocardiogram-gated-computed tomography angiography, with the blood velocity field computed by a smoothed particle hydrodynamics (SPH) numerical model. In the present work, the SPH model has been specifically adapted to the solution of the 3D Navier-Stokes equations inside a domain with boundaries of prescribed motion. Images of the abdominal…

Materials scienceTime FactorsQuantitative Biology::Tissues and OrgansPhysics::Medical PhysicsBiomedical EngineeringPulsatile flowHemodynamicsSettore ICAR/01 - IdraulicaPhysics::Fluid DynamicsAneurysmDiastolemedicine.arterymedicineShear stressPressureHumansComputer SimulationMolecular BiologyAortamedicine.diagnostic_testCardiac cycleApplied MathematicsHemodynamicsModels CardiovascularMechanicsmedicine.diseaseAbdominal aortic aneurysmBiomechanical PhenomenaComputational Theory and MathematicsModeling and SimulationAngiographycardiovascular systemHydrodynamicsStress MechanicalInfrarenal abdominal aorta aneurysm shear stresses arterial wall SPH moving boundarySoftwareAlgorithmsBlood Flow VelocityAortic Aneurysm AbdominalInternational journal for numerical methods in biomedical engineeringREFERENCES
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Designing voltage multipliers with nanofluidic diodes immersed in aqueous salt solutions.

2016

[EN] Membranes with nanofluidic diodes allow the selective control of molecules in physiological salt solutions at ambient temperature. The electrical coupling of the membranes with conventional electronic elements such as capacitors suggests opportunities for the external monitoring of sensors and actuators. We demonstrate experimentally and theoretically the voltage multiplier functionality of simple electrical networks composed of membranes with conical nanopores coupled to load capacitors. The robust operation of half and full wave voltage multipliers is achieved in a broad range of experimental conditions (single pore and multipore membranes, electrolyte concentrations, voltage amplitu…

Materials sciencebusiness.industryAnalytical chemistryGeneral Physics and Astronomy02 engineering and technologyElectrolyte010402 general chemistry021001 nanoscience & nanotechnology01 natural sciences0104 chemical scienceslaw.inventionQuantitative Biology::Subcellular ProcessesCapacitorNanoporeMembranelawElectrical networkFISICA APLICADAVoltage multiplierOptoelectronicsPhysical and Theoretical Chemistry0210 nano-technologybusinessVoltageDiodePhysical chemistry chemical physics : PCCP
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Analysis of multi-spectral photoplethysmograph biosensors

2013

Multi-spectral photoplethysmograph biosensor intended for analysis of peripheral blood volume pulsations at different vascular depths has been experimentally tested. Light emitting diodes with four different wavelengths were used as the light emitters. A single photodiode with multi-channel signal output processing was used as the light detector. This study analyzed rising time difference between wavelengths at systole maximum, wavelengths relations between systole and diastole peak difference. The proposed methodology is discussed.

Materials sciencebusiness.industryInfraredQuantitative Biology::Tissues and OrgansPhysics::Medical PhysicsDiastolePhysics::OpticsSignallaw.inventionPhotodiodeWavelengthOpticslawPhotoplethysmogramOptoelectronicsbusinessBiosensorLight-emitting diode
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Evaluation of the apical sealing ability and adaptation to the dentin of two resin-based Sealers: An in vitro study

2013

Aim: To quantitatively evaluate the apical sealing ability and adaptation of two resin-based sealers to dentin. Materials and Methods: Fifty freshly extracted mandibular first premolars were taken and sectioned at the cemento-enamel junction. Thirty teeth were subjected to a leakage study by the resin infiltration method with two groups of 10 teeth each. Group I teeth were obturated with methacrylate resin-based sealer (EnoRez) and Group II teeth were obturated with epoxy resin-based sealer (AH Plus). The remaining 10 teeth were used as controls (positive and negative of five teeth each). Twenty teeth were divided into two groups and obturated as in the leakage study and subjected to a scan…

Materials sciencebusiness.industryRoot canalPhysical integrityGroup iiResin infiltrationDentistryquantitative methodstomatognathic diseasesmedicine.anatomical_structurestomatognathic systemMicroleakageresin sealerSealer penetrationmedicineDentinIn vitro studyElectronic microscopyOriginal ArticlebusinessGeneral DentistryJournal of Conservative Dentistry : JCD
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Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy

2022

Light-sheet fluorescence microscopy (LSFM) enables real-time whole-brain functional imaging in zebrafish larvae. Conventional one photon LSFM can however induce undesirable visual stimulation due to the use of visible excitation light. The use of two-photon (2P) excitation, employing near-infrared invisible light, provides unbiased investigation of neuronal circuit dynamics. However, due to the low efficiency of the 2P absorption process, the imaging speed of this technique is typically limited by the signal-to-noise-ratio. Here, we describe a 2P LSFM setup designed for non-invasive imaging that enables quintuplicating state-of-the-art volumetric acquisition rate of the larval zebrafish bra…

Materials scienceepilepsy zebrafish calcium imaging light sheet imaging two photon imagingbrain01 natural sciencesQuantitative Biology - Quantitative MethodsArticle010309 optics03 medical and health scienceszebrafish brain imaging microscopy two-photon light sheetTwo-photon excitation microscopyNeuroimaging0103 physical sciencesZebrafish larvaeQuantitative Methods (q-bio.QM)030304 developmental biologytwo-photon0303 health sciencesimaginglight sheetzebrafishAtomic and Molecular Physics and OpticsSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)3. Good healthFOS: Biological sciencesLight sheet fluorescence microscopyQuantitative Biology - Neurons and CognitionBiophysicsmicroscopyNeurons and Cognition (q-bio.NC)Biotechnology
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A DNA-nanoparticle actuator enabling optical monitoring of nanoscale movements induced by an electric field.

2018

Merging biological and non-biological matter to fabricate nanoscale assemblies with controllable motion and function is of great interest due to its potential application, for example, in diagnostics and biosensing. Here, we have constructed a DNA-based bionanoactuator that interfaces with biological and non-biological matter via an electric field in a reversibly controllable fashion. The read-out of the actuator is based on motion-induced changes in the plasmon resonance of a gold nanoparticle immobilized to a gold surface by single stranded DNA. The motion of the gold nanoparticle and thus the conformational changes of the DNA under varying electric field were analyzed by dark field spect…

Materials scienceta221Immobilized Nucleic AcidsPhysics::OpticsNanoparticleDNA Single-StrandedMetal NanoparticlesNanotechnology02 engineering and technology010402 general chemistrySpectrum Analysis Raman01 natural sciencesnanobiotechnologyBiokemia solu- ja molekyylibiologia - Biochemistry cell and molecular biologyNanoteknologia - NanotechnologyElectricityElectric fieldGeneral Materials ScienceBiotinylationSurface plasmon resonanceSpectroscopyQuantitative Biology::Biomoleculesta114Optical ImagingnanobiotekniikkaDNASurface Plasmon Resonance021001 nanoscience & nanotechnologyAvidin0104 chemical sciencesNanostructuresColloidal goldNucleic Acid ConformationnanohiukkasetnanoparticlesGold0210 nano-technologyActuatorBiosensorVoltageNanoscale
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One- and multi-locus multi-allele selection models in a random environment

1979

We deduce conditions for stochastic local stability of general perturbed linear stochastic difference equations widely applicable in population genetics. The findings are adapted to evaluate the stability properties of equilibria in classical one- and multi-locus multi-allele selection models influenced by random temporal variation in selection intensities. As an example of some conclusions and biological interpretations we analyse a special one-locus multi-allele model in more detail.

Mathematical optimizationApplied MathematicsModeling and SimulationStochastic difference equationsRandom environmentPopulation geneticsApplied mathematicsLocus (genetics)Stochastic optimizationAlleleQuantitative Biology::GenomicsAgricultural and Biological Sciences (miscellaneous)MathematicsJournal of Mathematical Biology
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Numerical Simulation of a Contractivity Based Multiscale Cancer Invasion Model

2017

We present a problem-suited numerical method for a particularly challenging cancer invasion model. This model is a multiscale haptotaxis advection-reaction-diffusion system that describes the macroscopic dynamics of two types of cancer cells coupled with microscopic dynamics of the cells adhesion on the extracellular matrix. The difficulties to overcome arise from the non-constant advection and diffusion coefficients, a time delay term, as well as stiff reaction terms.

Mathematical optimizationComputer simulationQuantitative Biology::Tissues and OrgansNumerical analysisDynamics (mechanics)medicineCancerStatistical physicsDiffusion (business)medicine.diseaseHaptotaxisQuantitative Biology::Cell BehaviorMathematics
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A multi-sphere particle numerical model for non-invasive investigations of neuronal human brain activity

2013

In this paper, a multi-sphere particle method is built- up in order to estimate the solution of the Poisson's equation with Neumann boundary conditions describing the neuronal human brain activity. The partial difierential equations governing the relationships between neural current sources and the data produced by neuroimaging technique, are able to compute the scalp potential and magnetic fleld distributions generated by the neural activity. A numerical approach is proposed with current dipoles as current sources and going on in the computation by avoiding the mesh construction. The current dipoles are into an homogeneous spherical domain modeling the head and the computational approach i…

Mathematical optimizationCurrent (mathematics)Quantitative Biology::Neurons and CognitionComputer scienceComputationNon invasiveMathematical analysisDomain modelPoisson distributionElectronic Optical and Magnetic MaterialsDipolesymbols.namesakeBio-magnetic fields Human brain activity meshless numerical methodSettore ING-IND/31 - ElettrotecnicaNeumann boundary conditionsymbolsParticle
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On the shape of compact hypersurfaces with almost constant mean curvature

2015

The distance of an almost constant mean curvature boundary from a finite family of disjoint tangent balls with equal radii is quantitatively controlled in terms of the oscillation of the scalar mean curvature. This result allows one to quantitatively describe the geometry of volume-constrained stationary sets in capillarity problems.

Mathematics - Differential GeometryMean curvatureOscillationApplied MathematicsGeneral Mathematics010102 general mathematicsMathematical analysisScalar (mathematics)Boundary (topology)TangentMetric Geometry (math.MG)Disjoint sets01 natural sciences010101 applied mathematicsMathematics - Analysis of PDEsMean curvature capillarity theory quantitative estimates Alexandrov theorem.Differential Geometry (math.DG)Mathematics - Metric Geometry49Q10 49Q20 53A10FOS: MathematicsMathematics::Differential Geometry0101 mathematicsConstant (mathematics)Analysis of PDEs (math.AP)Mathematics
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