Search results for "r process"
showing 10 items of 665 documents
How to Prevent SARS-CoV-2 Transmission in the Agri-Food Industry during the First Pandemic Wave: Effects on Seroprevalence
2021
During the SARS-CoV-2 pandemic, many workplaces were forced to interrupt their activities or alternatively had to prefer a smart way of working, if this was compatible with their activities, to contain the spread of the virus. Some production activities, on the other hand, continued, such as those belonging to the agri-food sector. The aim of the study was to investigate seroprevalence in the workers of an Italian agri-food company following prevention interventions developed in concert with an occupational physician. An observational cohort study was conducted on a population of 328 (100%) workers of a company in the agri-food sector, located in the Sicilian region, which specialized in th…
Intra-Articular Hybrid Hyaluronic Acid Injection Treatment in Overweight Patients with Knee Osteoarthritis: A Single-Center, Open-Label, Prospective …
2021
Background: A BMI >
ETAS Space–Time Modeling of Chile Triggered Seismicity Using Covariates: Some Preliminary Results
2021
Chilean seismic activity is one of the strongest in the world. As already shown in previous papers, seismic activity can be usefully described by a space–time branching process, such as the ETAS (Epidemic Type Aftershock Sequences) model, which is a semiparametric model with a large time-scale component for the background seismicity and a small time-scale component for the triggered seismicity. The use of covariates can improve the description of triggered seismicity in the ETAS model, so in this paper, we study the Chilean seismicity separately for the North and South area, using some GPS-related data observed together with ordinary catalog data. Our results show evidence that the use of s…
Multi-Technique Diagnostic Investigation in View of the Restoration of “The Glory of St. Barbara” Painting by Mattia Preti
2022
The present paper illustrates the results of a diagnostic investigation performed on the oil on canvas painting “The Glory of St. Barbara” (1680–1688) by Mattia Preti. The painting is located inside the St. Barbara Church in Taverna (Catanzaro, Italy), the city that gave birth to the artist. In situ, non-invasive studies, by applying X-ray fluorescence (XRF) spectroscopy, along with laboratory micro-destructive analytical investigations, by employing electron probe microanalyses (EPMA) coupled with energy-dispersive spectrometry (EDS) and micro-Raman (µ-Raman) spectroscopy, were combined to retrieve the color palette and identify the painting technique and style of t…
Refrigeration of an array of cylindrical nanosystems by superfluid helium counterflow
2017
Abstract Motivated by the challenge of computer refrigeration, we study the limits set by the transition to quantum turbulence on the cooling of an array of heat-producing cylindrical nanosystems by means of superfluid-helium counterflow. The effective thermal conductivity in laminar counterflow superfluid helium is obtained in channels with rectangular cross section, through arrays of mutually parallel cylinders and in the combined situation of arrays of orthogonal cylinders inside the rectangular channel. The maximum cooling capacity is analyzed on the condition that turbulence is avoided and that the highest temperature does not exceed the lambda temperature.
Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging
2014
Dietary restriction extends longevity in organisms ranging from bacteria to mice and protects primates from a variety of diseases, but the contribution of each dietary component to aging is poorly understood. Here we demonstrate that glucose and specific amino acids promote stress sensitization and aging through the differential activation of the Ras/cAMP/PKA, PKH1/2 and Tor/S6K pathways. Whereas glucose sensitized cells through a Ras-dependent mechanism, threonine and valine promoted cellular sensitization and aging primarily by activating the Tor/S6K pathway and serine promoted sensitization via PDK1 orthologs Pkh1/2. Serine, threonine and valine activated a signaling network in which Sch…
Caspase-3 contributes to ZO-1 and Cl-5 tight-junction disruption in rapid anoxic neurovascular unit damage.
2011
BACKGROUND: Tight-junction (TJ) protein degradation is a decisive step in hypoxic blood-brain barrier (BBB) breakdown in stroke. In this study we elucidated the impact of acute cerebral ischemia on TJ protein arrangement and the role of the apoptotic effector protease caspase-3 in this context. METHODOLOGY/PRINCIPAL FINDINGS: We used an in vitro model of the neurovascular unit and the guinea pig whole brain preparation to analyze with immunohistochemical methods the BBB properties and neurovascular integrity. In both methodological approaches we observed rapid TJ protein disruptions after 30 min of oxygen and glucose deprivation or middle cerebral artery occlusion, which were accompanied by…
20 years of alveolar distraction : a systematic review of the literature
2018
Background The Vertical Alveolar Distraction Osteogenesis (VADO) technique is an excellent solution for bone and soft tissue neoformation in areas in which there has been significant bone atrophy that hinders normal rehabilitation using dental implants. The goal of this systematic review is to analyze the most relevant articles published on VADO in the literature over the past 20 years. Material and Methods The review was performed by using the keywords: “alveolar ridge”, “distraction ostegenesis” and “dental implant”. This search produced a total result of 240 articles. The clinical studies and cases reported in humans amounted to 113 articles, 18 articles referred to studies developed on …
Coating Toughness Estimation through a Laser Shock Testing in Ni-Cr-B-Si-C Coatings
2018
In the nuclear field, efforts are made to find substitutes to cobalt hardfacing alloys since these alloys have a principal drawback, the transmutation from stable 59Co to 60Co under neutron irradiation. In case of wear, fragments could be deposed on the surface of primary circuit and thus contaminate it, causing a real issue for deconstruction.
Acidic Environment Leads to ROS-Induced MAPK Signaling in Cancer Cells
2011
Tumor micromilieu often shows pronounced acidosis forcing cells to adapt their phenotype towards enhanced tumorigenesis induced by altered cellular signalling and transcriptional regulation. In the presents study mechanisms and potential consequences of the crosstalk between extra- and intracellular pH (pH(e), pH(i)) and mitogen-activated-protein-kinases (ERK1/2, p38) was analyzed. Data were obtained mainly in AT1 R-3327 prostate carcinoma cells, but the principle importance was confirmed in 5 other cell types. Extracellular acidosis leads to a rapid and sustained decrease of pH(i) in parallel to p38 phosphorylation in all cell types and to ERK1/2 phosphorylation in 3 of 6 cell types. Furth…