Search results for "rFVIIa"

showing 2 items of 2 documents

Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolong…

2014

Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolonged pharmacodynamic effect -

HeredityPharmacokinetic inherited Factor VII deficiencyFactor VII DeficiencySocio-culturaleFactor VIIaPharmacologySeverity of Illness IndexPharmacokineticsPredictive Value of Testshemic and lymphatic diseasesHumansMedicineGenetic Predisposition to DiseaseFVII deficiencyRegistriescardiovascular diseasesBlood CoagulationVolume of distributionbiologyCoagulantsbusiness.industryVascular biologyrFVIIaHematologyFactor VIIRecombinant ProteinsPhenotypeTreatment OutcomerFVIIa; FVII deficiency; pharmacokineticsRecombinant factor VIIaPharmacodynamicsbiology.proteinBlood Coagulation TestsSteady state (chemistry)Drug Monitoringbusinesspharmacokinetics
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Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy

2019

Key Clinical Message In our case, the use of a low intravenous bolus dose of rFVIIa (recombinant factor VII activated; 15‐20 mcg/kg) was effective and uneventful in controlling late postprocedural PDT bleeding associated with thrombocytopenia that cannot be corrected and after all other treatments failed.

lcsh:MedicineCase ReportCase Reports030204 cardiovascular system & hematologyIntravenous boluslaw.invention03 medical and health scienceschemistry.chemical_compound0302 clinical medicinelawActivated factor VIIpercutaneous tracheostomyMedicinepostoperatory bleedinglcsh:R5-920activated factor VIIFactor VIIbusiness.industrylcsh:RLow doserFVIIaGeneral MedicineThrombocytopeniaPercutaneous dilational tracheostomychemistry030220 oncology & carcinogenesisAnesthesiaPercutaneous tracheostomyRecombinant DNAlcsh:Medicine (General)businessClinical Case Reports
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