6533b831fe1ef96bd1299a31

RESEARCH PRODUCT

Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolonged pharmacodynamic effect.

M MorfiniA BatorovaG MarianiG AuerswaldFrancesco BernardiG Di MinnoA DolceC FedeM Giansily BlaizotJ IngerslevU MartinowitzM NapolitanoMirko PinottiJf Schved International Fvii [If7] Seven Treatment Evaluation Registry [Ster] Study Groups

subject

HeredityPharmacokinetic inherited Factor VII deficiencyFactor VII DeficiencySocio-culturaleFactor VIIaPharmacologySeverity of Illness IndexPharmacokineticsPredictive Value of Testshemic and lymphatic diseasesHumansMedicineGenetic Predisposition to DiseaseFVII deficiencyRegistriescardiovascular diseasesBlood CoagulationVolume of distributionbiologyCoagulantsbusiness.industryVascular biologyrFVIIaHematologyFactor VIIRecombinant ProteinsPhenotypeTreatment OutcomerFVIIa; FVII deficiency; pharmacokineticsRecombinant factor VIIaPharmacodynamicsbiology.proteinBlood Coagulation TestsSteady state (chemistry)Drug Monitoringbusinesspharmacokinetics

description

Pharmacokinetic properties of recombinant FVIIa in inherited FVII deficiency account for a large volume of distribution at steady state and a prolonged pharmacodynamic effect -

yearjournalcountryeditionlanguage
2014-01-01
http://hdl.handle.net/11588/595553