Search results for "radiolysis"

showing 10 items of 31 documents

A multifuctional nanoplatform for drug targeted delivery based on radiation-engineered nanogels

2020

Abstract Under a rational design, combining biologically active molecules, ligands to specific cell receptors and fluorescent, radioactive or paramagnetic labels into a single nano-object can bridge the unique properties of the individual components and improve conventional sensing, imaging and therapeutic efficacies. The validation of these functional nano-objects requires careful testing both in terms of physico-chemical properties and biological behaviour in vitro and in vivo, prior to translation into the clinic. Ionising radiation of aqueous polymer solutions is a viable strategy to produce multifunctional nanogels from aqueous solutions of hydrophilic polymers. By proper selection of …

COLON-CANCER CELLSPULSE-RADIOLYSISDrugINDUCED CROSS-LINKINGSPECTRAL PROPERTIESmedia_common.quotation_subjectNanogelsConjugation reactionsNanotechnology01 natural sciencesAQUEOUS-SOLUTIONFLUORESCEIN030218 nuclear medicine & medical imagingNanogel03 medical and health sciences0302 clinical medicineHydrophilic polymers0103 physical sciencesNANOPARTICLESMoleculeIonising radiation synthesiIN-VIVOmedia_commonchemistry.chemical_classificationRadiationAqueous solution010308 nuclear & particles physicsIonising radiation synthesisRational designPolymerINSULINNanomedicineConjugation reactionchemistryDrug deliveryDrug deliveryNanomedicineSettore CHIM/07 - Fondamenti Chimici Delle TecnologieACID) NANOGELSRadiation Physics and Chemistry
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Nd:YAG laser induced E′ centers probed by in situ absorption measurements

2005

We investigated various types of commercial silica irradiated with a pulsed Nd:YAG laser radiation (4.66 eV), with exposure time ranging up to 10000 s. Transient E' centers were probed in situ by measuring the amplitude of the optical absorption band at 5.8 eV (due to E' centers) both during and after irradiation. The laser-induced absorption is observed only in natural samples, whereas the synthetic materials exhibit high toughness to radiation effect. The reported results evidence that the kinetics of E' centers is influenced by their reaction with diffusing molecular hydrogen H2 made available by dimerization of radiolytic H0.

Condensed Matter - Materials ScienceAbsorption spectroscopyChemistryKineticsAnalytical chemistryMaterials Science (cond-mat.mtrl-sci)FOS: Physical sciencesCondensed Matter PhysicsLaserElectronic Optical and Magnetic Materialslaw.inventionAbsorption bandlawNd:YAG laserRadiolysisMaterials ChemistryCeramics and CompositesIrradiationAbsorption (electromagnetic radiation)Journal of Non-Crystalline Solids
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Stability of E' centers induced by 4.7eV laser radiation in SiO2

2007

The kinetics of E' centers (silicon dangling bonds) induced by 4.7eV pulsed laser irradiation in dry fused silica was investigated by in situ optical absorption spectroscopy. The stability of the defects, conditioned by reaction with mobile hydrogen of radiolytic origin, is discussed and compared to results of similar experiments performed on wet fused silica. A portion of E' and hydrogen are most likely generated by laser-induced breaking of Si-H precursors, while an additional fraction of the paramagnetic centers arise from another formation mechanism. Both typologies of E' participate to the reaction with H_2 leading to the post-irradiation decay of the defects. This annealing process is…

Condensed Matter - Materials ScienceAbsorption spectroscopyHydrogenAnnealing (metallurgy)Kineticschemistry.chemical_elementPhysics::OpticsMaterials Science (cond-mat.mtrl-sci)FOS: Physical sciencesDisordered Systems and Neural Networks (cond-mat.dis-nn)Condensed Matter - Disordered Systems and Neural NetworksCondensed Matter PhysicsPhotochemistryLaserElectronic Optical and Magnetic Materialslaw.inventionParamagnetismNuclear magnetic resonancechemistrylawRadiolysisMaterials ChemistryCeramics and CompositesElectron paramagnetic resonance
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Influence of Pressure and Temperature on X-Ray Induced Photoreduction of Nanocrystalline CuO

2018

The authors are grateful to Prof. Alain Polian for providing NDAC cell. Parts of the present research have been carried out at the ODE beamline at SOLEIL.

Copper oxideMaterials sciencehigh-pressureQC1-999Analytical chemistryGeneral Physics and Astronomyradiolysis02 engineering and technologyx-ray absorption spectroscopy010402 general chemistry01 natural scienceschemistry.chemical_compound:NATURAL SCIENCES:Physics [Research Subject Categories]X-ray absorption spectroscopyPhysicsGeneral EngineeringOdeX-rayX-ray absorption spectroscopy021001 nanoscience & nanotechnologyNanocrystalline materialcopper oxide0104 chemical scienceschemistryBeamlineHigh pressureRadiolysisnanocrystalline0210 nano-technologyLatvian Journal of Physics and Technical Sciences
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Properties of HO2• radicals induced by γ-ray irradiation in silica nanoparticles

2014

Abstract We report an experimental investigation on the effects of γ -ray irradiation in several types of silica nanoparticles previously loaded with O 2 molecules. They differ in specific surface and average diameter. By electron paramagnetic resonance (EPR) measurements we observe the generation of about 10 18 HO 2 • /cm 3 interstitial radicals. These radicals are induced by reaction of interstitial O 2 molecules with radiolytic H atoms, as previously suggested for O 2 -loaded bulk a-SiO 2 samples. However, at variance with respect to bulk materials, our experimental evidences suggest a different generation process of HO 2 • radical. In fact, by a detailed study of samples exposed to D 2 …

HO2•; O2; Fumed silica; Electron paramagnetic resonance spectroscopy; Raman spectroscopyChemistryRadicalAnalytical chemistryNanoparticleO2Condensed Matter PhysicsElectronic Optical and Magnetic Materialslaw.inventionParamagnetismsymbols.namesakelawHO2•RadiolysisRaman spectroscopyMaterials ChemistryCeramics and CompositessymbolsMoleculePhysical chemistryFumed silicaIrradiationElectron paramagnetic resonanceRaman spectroscopyElectron paramagnetic resonance spectroscopy
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Self-Radiolysis of Tritiated Water: Experimental Study and Simulation

2005

Radioactive decay of tritium contained in tritiated water leads to the production of gaseous helium and, through self-radiolysis, to the formation of molecular hydrogen and oxygen. For safety management of tritiated water storage, it is essential to be able to predict pressure increase resulting from this phenomenon. The present study aims to identify the mechanisms that take place in self-radiolysis of chemically pure liquid tritiated water. The evolution of the concentration of hydrogen and oxygen in the gas phase of closed vessels containing tritiated water has been followed experimentally. Simulation of pure water radiolysis has been carried out using data from the literature. In order …

Heavy waterNuclear and High Energy PhysicsReaction mechanismMaterials scienceTritiated waterHydrogen020209 energyMechanical EngineeringRadiochemistrychemistry.chemical_element02 engineering and technology01 natural sciencesOxygen010305 fluids & plasmasNuclear physicschemistry.chemical_compoundNuclear Energy and Engineeringchemistry0103 physical sciencesRadiolysis0202 electrical engineering electronic engineering information engineeringGeneral Materials ScienceTritiumHeliumCivil and Structural EngineeringFusion Science and Technology
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Investigation on the ganaration process of HO2• radicals by γ-ray irradiation in O2-loaded fumed silica

2013

Abstract We report an experimental investigation on the effects of γ-ray irradiation in three types of fumed silica previously loaded with O 2 molecules. Our data indicate that the main effect of irradiation in these systems is to generate a very large concentration of HO 2 interstitial radicals (about 10 18  molecules/cm 3 ). Furthermore, the number of generated HO 2 was found to be larger in the samples with higher O 2 contents before irradiation. This correlation suggests that HO 2 radicals are induced by reaction of interstitial O 2 molecules with radiolytic H atoms, as previously suggested for O 2 -loaded bulk amorphous silicon dioxide (a-SiO 2 or silica) samples. However, at variance …

HydrogenChemistryRadicalchemistry.chemical_elementO2Condensed Matter PhysicsPhotochemistryOxygenElectronic Optical and Magnetic Materialslaw.inventionlawHO2•RadiolysisRaman spectroscopyMaterials ChemistryCeramics and CompositesOrganic chemistryMoleculeFumed silicaIrradiationElectron paramagnetic resonanceElectron paramagnetic resonance spectroscopyFumed silica
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Influence of hydrogen on paramagnetic defects induced by UV laser exposure in natural silica

2005

Diffusion limited reactions of point defects were investigated in amorphous SiO2 exposed to UV laser light. Electron spin resonance and in situ absorption measurements at room temperature evidenced the annealing of E' centers and the growth of H(II) centers both occurring in the post-irradiation stage and lasting a few hours. These transients are caused by reactions involving molecular hydrogen H2, made available by dimerization of radiolytic H0.

In situCondensed Matter - Materials ScienceMaterials scienceHydrogenAnnealing (metallurgy)Materials Science (cond-mat.mtrl-sci)FOS: Physical scienceschemistry.chemical_elementPhotochemistryCrystallographic defectlaw.inventionAmorphous solidParamagnetismUV laserchemistrylawRadiolysisnatural silicaElectron paramagnetic resonanceHydrogen
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Radiation-Engineered Functional Nanoparticles in Aqueous Systems.

2015

Controlled synthesis of nanoscalar and nanostructured materials enables the development of novel functional materials with fine-tuned optical, mechanical, electronic, magnetic, conductive and catalytic properties that are of use in numerous applications. These materials have also found their potential use in medicine as vehicles for drug delivery, in diagnostics or in combinations thereof. In principle, nanoparticles can be divided into two broad categories, organic and inorganic nanoparticles. For both types of nanoparticles there are numerous possible synthetic routes. Considering the large difference in nature of these materials and the elementary reactions involved in the synthetic rout…

Ionizing radiationReaction mechanismAqueous solutionMaterials scienceIonizing Radiation Water Radiolysis Functional NanoparticlesBiomedical EngineeringNanoparticleBioengineeringNanotechnologyGeneral ChemistryRadiation chemistryCondensed Matter PhysicsWater radiolysisNanomaterialsParticleGeneral Materials ScienceReactivity (chemistry)IrradiationSettore CHIM/07 - Fondamenti Chimici Delle TecnologieFunctional nanoparticles.Journal of nanoscience and nanotechnology
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Polymerization reactions and modifications of polymers by ionizing radiation

2020

International audience; Ionizing radiation has become the most effective way to modify natural and synthetic polymers through crosslinking, degradation, and graft polymerization. This review will include an in-depth analysis of radiation chemistry mechanisms and the kinetics of the radiation-induced C-centered free radical, anion, and cation polymerization, and grafting. It also presents sections on radiation modifications of synthetic and natural polymers. For decades, low linear energy transfer (LLET) ionizing radiation, such as gamma rays, X-rays, and up to 10 MeV electron beams, has been the primary tool to produce many products through polymerization reactions. Photons and electrons in…

Kinetic chain lengthMaterials sciencePolymers and PlasticsReview02 engineering and technologyDegree of polymerizationRadiation chemistryPhotochemistry01 natural scienceslcsh:QD241-441chemistry.chemical_compoundlcsh:Organic chemistry0103 physical sciencesIrradiationradiation of natural polymerschemistry.chemical_classification010308 nuclear & particles physicsGeneral ChemistryPolymer[CHIM.MATE]Chemical Sciences/Material chemistryradiation induced polymerization021001 nanoscience & nanotechnologyradiation induced graftingIonizing radiation Radiation induced grafting Radiation induced polymerization Radiation of natural polymers Radiation synthesis nanogelsradiation synthesis nanogelsMonomer[CHIM.POLY]Chemical Sciences/PolymerschemistryPolymerizationRadiolysisSettore CHIM/07 - Fondamenti Chimici Delle Tecnologieionizing radiation0210 nano-technology
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