Search results for "ratifica"
showing 10 items of 258 documents
Playing with accents
2020
While certain ways of speaking or varieties of English – such as American English or British English – evoke associations of modernity, higher education and urbanity in Uganda, others – such as Ugandan English with strong northern or western accents – stand for backwardness, social strata remote from education and ‘village identities’. Yet concepts of backwardness or modernity are not only based on linguistic criteria but also associated with a specific worldview, contributing to complex signs of higher-order indexicality. In contrast, speakers’ practices of enregisterment reveal how fluid and contextual these indices of urbanity and rurality actually are. Considering diverse repertoires of…
Openness to experience as a predictor of L2 WTC
2018
Abstract This paper aims to provide empirical evidence for the relationship between openness to experience and L2 willingness to communicate (WTC). The study posits that openness as a personality dimension may have a dual effect—both direct and indirect—on one's L2 WTC levels. First, openness directly influences L2 WTC through its stable character, shaping one's cognition, affect and behaviour. Also, it has a possible dual indirect impact by mediating perceived communicative competence and language anxiety. According to the results of step-wise multiple regression, openness can be regarded a significant predictor of L2 WTC, explaining 21% of its variability. It may be concluded that student…
La Muestra Continua de Vidas Laborales (MCVL) como fuente generadora de datos para el estudio del sistema de pensiones
2015
Esta tesis tiene como elemento fundamental de análisis la denominada Muestra Continua de Vidas Laborales (MCVL), como fuente generadora de datos para el estudio del sistema de público de pensiones de España. La MCVL es un conjunto de microdatos individuales anonimizados extraídos de los registros de la Seguridad Social de España. La MCVL se obtiene a partir de un Muestreo Aleatorio Simple (MAS) sobre la población de referencia (conjunto de personas relacionadas durante todo el año con la Seguridad Social, bien como afiliadas o bien como perceptoras de prestaciones, pero con ciertos matices en dicha relación). Los objetivos principales de esta tesis son: - Contribuir a aumentar el conocimien…
Evolución de la normativa de la investigación Biomédica en España
2018
The ratification by the Spanish State of the ?Oviedo Convention? in 1999 implies a commitment to adapt to the legislation on biomedicine, since the normative instruments that respect it: guarantee the rights and fundamental freedoms of all and ensure dignity and identity of human beings. The object of this paper is the analysis of the Spanish normative norm in the field of research in human beings.
Evaluation of Risk Stratification Markers and Models in Acute Pulmonary Embolism: Rationale and Design of the MARS-PE (Mainz Retrospective Study of P…
2018
An acute pulmonary embolism (PE) is a crucial event in patients’ life and connected with serious morbidity and mortality. Regarding a high case-fatality rate, early and accurate risk-stratification is crucial. Risk for mortality and complications are closely related to hemodynamic stability and cardiac adaptations. The currently recommended risk-stratification approach is not overall simple to use and might delay the identification of those patients, who should be monitored more closely and may treated with more aggressive treatment strategies. Additionally, some risk-stratification criteria for the imaging procedures are still imprecise. Summarized, the search for the most effective risk-s…
Cardiovascular Risk in Polycythemia Vera: Thrombotic Risk and Survival: Can Cytoreductive Therapy Be Useful in Patients with Low-Risk Polycythemia Ve…
2019
<b><i>Background/Aims:</i></b> Cardiovascular risk factors are not considered in the current scores for evaluation of the thrombotic risk in myeloproliferative neoplasms, and in polycythemia vera (PV) in particular. Cytoreduction is currently not indicated in low-risk patients with PV, despite the absence or presence of cardiovascular risk factors. Our purpose is to highlight how cardiovascular risk factors in patients with PV increase the thrombotic risk both in low- and high-risk patients. <b><i>Methods:</i></b> We collected and analyzed data from 165 consecutive patients with a diagnosis of PV followed at our institution and compared the fr…
Comparison of RNA-seq and microarray-based models for clinical endpoint prediction
2015
Background Gene expression profiling is being widely applied in cancer research to identify biomarkers for clinical endpoint prediction. Since RNA-seq provides a powerful tool for transcriptome-based applications beyond the limitations of microarrays, we sought to systematically evaluate the performance of RNA-seq-based and microarray-based classifiers in this MAQC-III/SEQC study for clinical endpoint prediction using neuroblastoma as a model. Results We generate gene expression profiles from 498 primary neuroblastomas using both RNA-seq and 44 k microarrays. Characterization of the neuroblastoma transcriptome by RNA-seq reveals that more than 48,000 genes and 200,000 transcripts are being …
The Prevalence and Gratification of Nude Self-Presentation of Men Who Have Sex with Men in Online-Dating Environments: Attracting Attention, Empowerm…
2017
This study builds on research about the importance of body presentation among men who have sex with men (MSM) by exploring the phenomenon of nude body presentation in online dating environments. In a quantitative survey of N = 9,235 MSM users of a gay online dating site (ODS) in Germany, the prevalence of nude pictures and gratifications sought while displaying them were investigated. About two-thirds of the participants declared that they use nude pictures in their dating profiles, with only small differences in prevalence between members of different ages, education levels, and sexual orientation. Furthermore, the results indicate that the use of nudity is driven by three underlying grati…
Antithrombotic treatment in real-life atrial fibrillation patients: a report from the Euro Heart Survey on Atrial Fibrillation
2006
Aims To describe guideline adherence and application of different stroke risk stratification schemes regarding antithrombotic therapy in real-life atrial fibrillation (AF) patients and to assess which factors influence antithrombotic management decisions. Methods and results The Euro Heart Survey enrolled 5333 AF patients in 35 countries, in 2003 and 2004. Prescription of antithrombotic drugs, especially oral anticoagulation (OAC), was hardly tailored to the patient's stroke risk profile as indicated by the joint guidelines of the American College of Cardiology, American Heart Association, and the European Society of Cardiology, ACCP guidelines, or CHADS2 and Framingham risk scores. In mult…
Stratification for Identification of Prognostic Categories In the Acute RESpiratory Distress Syndrome (SPIRES) Score.
2021
OBJECTIVES: To develop a scoring model for stratifying patients with acute respiratory distress syndrome into risk categories (Stratification for identification of Prognostic categories In the acute RESpiratory distress syndrome score) for early prediction of death in the ICU, independent of the underlying disease and cause of death. DESIGN: A development and validation study using clinical data from four prospective, multicenter, observational cohorts. SETTING: A network of multidisciplinary ICUs. PATIENTS: One-thousand three-hundred one patients with moderate-to-severe acute respiratory distress syndrome managed with lung-protective ventilation. INTERVENTIONS: None. MEASUREMENTS AND MAIN …