Search results for "readmission"

showing 10 items of 61 documents

Short-Term Effects of Hypertonic Saline Solution in Acute Heart Failure and Long-Term Effects of a Moderate Sodium Restriction in Patients With Compe…

2011

INTRODUCTION: Hypertonic saline solution (HSS) and a moderate Na restriction plus high furosemide dose showed beneficial effects in compensated heart failure (HF), in short and long terms. The study was aimed to verify the effects of this combination on hospitalization time, readmissions and mortality in patients in New York Heart Association (NYHA) class III. METHOD: Chronic ischemic or nonischemic cardiomyopathy uncompensated patients with HF in NYHA III functional class with ejection fraction <40%, serum creatinine <2.5 mg/dL, blood urea nitrogen <60 mg/dL and reduced urinary volume were single-blind randomized in 2 groups: the first group received a 30-minute intravenous infusion of fur…

Malemedicine.medical_specialtyHeart diseasemedicine.medical_treatmentDiuresisPatient ReadmissionFurosemideInternal medicinemedicineHumansInfusions IntravenousAgedAged 80 and overHeart FailureSaline Solution HypertonicEjection fractionbusiness.industrySodiumFurosemideGeneral MedicineDiet Sodium-RestrictedMiddle Agedmedicine.diseaseHyepertonic saline heart failure diureticsDiuresisSurgeryHospitalizationTreatment OutcomeHeart failureCirculatory systemCardiologyTonicityFemaleDiureticbusinessmedicine.drugThe American Journal of the Medical Sciences
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Echocardiographic pulmonary artery pressure estimation and heart failure rehospitalization burden in patients with acute heart failure

2017

Abstract Pulmonary hypertension (PH) is a strong predictor of mortality in patients with heart failure (HF). However, the relationship between PH, through echocardiographic pulmonary artery pressure (PASP) estimation, and the risk of HF rehospitalizations remains unclear. Methods We prospectively included 2343 consecutive patients discharged for acute heart failure (AHF). PH was estimated by echocardiography through PASP determination during the index admission. Patients were categorized as follows across PASP: non-measurable, normal (≤35mmHg), mild (36–45mmHg), moderate (46–60mmHg), or severe PH (>60mmHg). Negative binomial regression method was used to evaluate the association between PAS…

Malemedicine.medical_specialtyHypertension PulmonaryPulmonary Artery030204 cardiovascular system & hematologyPatient ReadmissionCohort Studies03 medical and health sciences0302 clinical medicineInterquartile rangeInternal medicinemedicine.arteryHumansMedicineProspective Studies030212 general & internal medicineProspective cohort studyAgedAged 80 and overHeart FailureEjection fractionbusiness.industryMiddle Agedmedicine.diseasePulmonary hypertensionConfidence intervalEchocardiographyHeart failureAcute DiseasePulmonary arteryCardiologyFemaleCardiology and Cardiovascular MedicinebusinessFollow-Up StudiesCohort studyInternational Journal of Cardiology
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Prognostic Value of Brain Natriuretic Peptide in Acute Heart Failure: Mortality and Hospital Readmission

2008

The prognostic value of brain natriuretic peptide (BNP) measurement in patients with acute heart failure is not well understood. The aim of this study was to investigate the relationship between the BNP level and mortality and readmission for acute heart failure. We studied 569 consecutive patients who were admitted with a diagnosis of acute heart failure. The BNP level was measured after the patient became clinically stable. The relationship between the BNP level and mortality was assessed by Cox regression analysis, and the relationship with readmission, by competing risks regression analysis. During a median follow-up period of 9 (range, 3-18) months, 156 deaths (27.4%) and 140 readmissi…

Malemedicine.medical_specialtyMultivariate analysismedicine.drug_classPatient ReadmissionInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideHumansIn patientProspective Studiescardiovascular diseasesProspective cohort studyHeart FailureHospital readmissionProportional hazards modelbusiness.industryGeneral MedicineMiddle AgedPrognosisBrain natriuretic peptidemedicine.diseaseHeart failureAcute DiseaseCardiologyFemalebusinesshuman activitieshormones hormone substitutes and hormone antagonistsRevista Española de Cardiología (English Edition)
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Characteristics of advanced cancer patients who were readmitted to an acute palliative/supportive care unit

2017

Objectives: The aim of this study was to assess the characteristics of patients readmitted to an acute supportive/palliative care unit (ASPCU), the reasons for readmission, and the outcome after receiving specialistic assessment and treatment. Methods: A consecutive sample of patients was assessed for a period of 10 months. Epidemiological characteristics, including age, gender, Karnofsky level, diagnosis, caregivers, education, disease awareness, kind of admission, and anticancer treatment in the previous 30 days, were recorded, as well as hospital stay, death, and discharge at home. The principal reasons for admission were recorded. Symptom intensity and opioid doses, expressed as oral …

Malemedicine.medical_specialtyPalliative careCritical CarePain medicineSymptomDiseasePatient Readmission03 medical and health sciences0302 clinical medicineNeoplasmsEpidemiologymedicineHumans030212 general & internal medicineAgedbusiness.industryPalliative CareSymptom burdenAdvanced cancerOpioidOncologyAnticancer treatment030220 oncology & carcinogenesisEmergency medicineNeoplasmFemalebusinessReadmissionSupportive caremedicine.drugHuman
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Length of stay and risk of very early readmission in acute heart failure

2016

In patients admitted for acute heart failure (AHF), optimal length of stay (LOS) remains controversial. Longer hospitalizations are associated with worse prognosis, but little is known about short hospitalizations. The aim of this work was to evaluate the relationship between LOS and the risk of short-term readmission in patients discharged after a hospitalization for AHF.We included 2110 consecutive patients. The independent associations between LOS and unplanned 10, 15 and 30-day readmissions were evaluated by Cox regression analysis adjusted for competing events. LOS was categorized as LOS1: ≤4days, LOS2: 5-7days, LOS3: 8-10days, and LOS4:10days.The mean age was 73±11years and 52.6% exhi…

Malemedicine.medical_specialtyTime FactorsMultivariate analysis030204 cardiovascular system & hematologyPatient ReadmissionVentricular Function Left03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineInternal MedicinemedicineHumansIn patientProspective Studies030212 general & internal medicineAgedProportional Hazards ModelsAged 80 and overHeart FailureAmino-terminal pro-brain natriuretic peptideEjection fractionbusiness.industryProportional hazards modelMean ageLength of StayMiddle Agedmedicine.diseasemedicine.anatomical_structureSpainVentricleHeart failureAcute DiseaseMultivariate AnalysisCardiologyFemalebusinessEuropean Journal of Internal Medicine
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Clozapine plasma level monitoring for prediction of rehospitalization schizophrenic outpatients.

2011

INTRODUCTION: The aim of this naturalistic exploratory study was to examine whether blood antipsychotic drug concentrations can predict rehospitalizations in chronically medicated patients. METHODS: The study included schizophrenic outpatients under clozapine (CLZ) maintenance treatment, supervised by therapeutic drug monitoring (TDM). Patients were observed for a period of 21 months. Their on average monthly measured plasma levels and the date of rehospitalizations were recorded. The variability of the first 3 CLZ plasma levels, measured in 3.6 months, was compared between patients with and without rehospitalization. RESULTS: 23 patients participated of which 6 patients were rehospitalized…

Malemedicine.medical_specialtyTime FactorsPatient ReadmissionMaintenance therapyRecurrenceInternal medicineOutpatientsmedicineHumansPharmacology (medical)In patientAntipsychotic drugClozapineClozapinemedicine.diagnostic_testbusiness.industryGeneral MedicinePlasma levelsmedicine.diseaseSurgeryHospitalizationPsychiatry and Mental healthSchizophreniaTherapeutic drug monitoringPlasma concentrationSchizophreniaFemaleDrug Monitoringbusinessmedicine.drugAntipsychotic AgentsPharmacopsychiatry
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Serum Neprilysin and Recurrent Admissions in Patients With Heart Failure

2017

Background Our aim was to evaluate the association between the soluble form of neprilysin ( sNEP ) levels and long‐term all‐cause, cardiovascular, and acute heart failure ( AHF ) recurrent admissions in an ambulatory cohort of patients with heart failure. sNEP has emerged as a new biomarker with promising implications for prognosis and therapy in patients with heart failure. Reducing the recurrent admission rate of heart failure patients has become an important target of public health planning strategies. Methods and Results We measured sNEP levels in 1021 consecutive ambulatory heart failure patients. End points were the number of all‐cause, cardiovascular, and AHF hospitalizations during…

Malemedicine.medical_specialtyTime Factorsmedicine.drug_class030204 cardiovascular system & hematologyPatient Readmissionneprilysin03 medical and health sciences0302 clinical medicinePredictive Value of TestsRisk FactorsInterquartile rangeCause of DeathInternal medicineNatriuretic Peptide BrainmedicineNatriuretic peptideHumans030212 general & internal medicineAgedOriginal ResearchAged 80 and overHeart Failurereadmissionbusiness.industryIncidenceMiddle AgedPrognosismedicine.diseasePeptide FragmentsConfidence intervalUp-RegulationQuartileSpainHeart failureCohortAmbulatoryCardiologyBiomarker (medicine)FemaleNeprilysinCardiology and Cardiovascular MedicinebusinessReadmissionBiomarkers
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Effect of a Strategy of Comprehensive Vasodilation vs Usual Care on Mortality and Heart Failure Rehospitalization Among Patients With Acute Heart Fai…

2019

Importance Short-term infusions of single vasodilators, usually given in a fixed dose, have not improved outcomes in patients with acute heart failure (AHF). Objective To evaluate the effect of a strategy that emphasized early intensive and sustained vasodilation using individualized up-titrated doses of established vasodilators in patients with AHF. Design, Setting, and Participants Randomized, open-label blinded-end-point trial enrolling 788 patients hospitalized for AHF with dyspnea, increased plasma concentrations of natriuretic peptides, systolic blood pressure of at least 100 mm Hg, and plan for treatment in a general ward in 10 tertiary and secondary hospitals in Switzerland, Bulgari…

Malemedicine.medical_specialtyVasodilator AgentsComorbidityPatient Readmission01 natural sciencesDrug Administration Schedulelaw.invention03 medical and health sciences0302 clinical medicineRandomized controlled triallawCause of DeathInternal medicineClinical endpointHumansMedicine030212 general & internal medicine0101 mathematicsAdverse effectAgedCause of deathAged 80 and overHeart Failurebusiness.industry010102 general mathematicsHazard ratioGeneral Medicinemedicine.diseaseHospitalizationBlood pressureHeart failureAcute DiseaseFemalebusinessSacubitril ValsartanJAMA
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Burden of Recurrent Hospitalizations Following an Admission for Acute Heart Failure: Preserved Versus Reduced Ejection Fraction.

2017

Abstract Introduction and objectives Heart failure with preserved ejection fraction and reduced ejection fraction share a high mortality risk. However, differences in the rehospitalization burden over time between these 2 entities remains unclear. Methods We prospectively included 2013 consecutive patients discharged for acute heart failure. Of these, 1082 (53.7%) had heart failure with preserved ejection fraction and 931 (46.2%) had heart failure with reduced ejection fraction. Cox and negative binomial regression methods were used to evaluate the risks of death and repeat hospitalizations, respectively. Results At a median follow-up of 2.36 years (interquartile range: 0.96-4.65), 1018 pat…

Malemedicine.medical_specialtyanimal structures030204 cardiovascular system & hematologyPatient Readmission03 medical and health sciencesVentricular Dysfunction Left0302 clinical medicineCost of IllnessInterquartile rangeRecurrenceInternal medicinemedicineHumans030212 general & internal medicineAgedHeart FailureEjection fractionbusiness.industryStroke VolumeGeneral Medicinemedicine.diseaseConfidence intervalHospitalizationHeart failureAcute DiseaseCardiologyFemalebusinessHeart failure with preserved ejection fractionRevista espanola de cardiologia (English ed.)
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Normal-sodium diet compared with low-sodium diet in compensated congestive heart failure: is sodium an old enemy or a new friend?

2007

The aim of the present study was to evaluate the effects of a normal-sodium (120 mmol sodium) diet compared with a low-sodium diet (80 mmol sodium) on readmissions for CHF (congestive heart failure) during 180 days of follow-up in compensated patients with CHF. A total of 232 compensated CHF patients (88 female and 144 male; New York Heart Association class II–IV; 55–83 years of age, ejection fraction &amp;lt;35% and serum creatinine &amp;lt;2 mg/dl) were randomized into two groups: group 1 contained 118 patients (45 females and 73 males) receiving a normal-sodium diet plus oral furosemide [250–500 mg, b.i.d. (twice a day)]; and group 2 contained 114 patients (43 females and 71 males) recei…

Malemedicine.medical_specialtyfood.dietLow sodium dietPlasma renin activityGastroenterologyPatient Readmissionchemistry.chemical_compoundfoodFurosemideInternal medicineNatriuretic Peptide BrainReninmedicineHumansDiureticsAldosteroneAgedAged 80 and overHeart FailureEjection fractionAldosteronebusiness.industryFurosemideSodium DietaryGeneral MedicineDiet Sodium-RestrictedMiddle Agedmedicine.diseaseBrain natriuretic peptideCombined Modality TherapySurvival AnalysisEndocrinologyTreatment OutcomechemistryHeart failureFemalebusinessmedicine.drugLow sodiumFollow-Up StudiesClinical science (London, England : 1979)
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