Search results for "recte"

showing 10 items of 463 documents

Information transfer in QT-RR dynamics: Application to QT-correction

2018

ABSTRACTThe relation between the electrical properties of the heart and the beating rate is essential for the heart functioning. This relation is central when calculating the “corrected QT interval” — an important measure of the risk of potentially lethal arrhythmias. We use the transfer entropy method from information theory to quantitatively study the mutual dynamics of the ventricular action potential duration (the QT interval) and the length of the beat-to-beat (RR) interval. We show that for healthy individuals there is a strong asymmetry in the information transfer: the information flow from RR to QT dominates over the opposite flow (from QT to RR), i.e. QT depends on RR to a larger e…

AdultMaleInformation transfermedicine.medical_specialtyCorrection methodEntropyHeart Ventricles0206 medical engineeringAction Potentialslcsh:Medicine02 engineering and technology030204 cardiovascular system & hematology3121 Internal medicine114 Physical sciencesQT intervalArticleElectrocardiography03 medical and health sciences0302 clinical medicineHeart RateLääketieteen bioteknologia - Medical biotechnologyInternal medicinemedicineHumanslcsh:ScienceAgedMathematicsBeating rateMultidisciplinarylcsh:RSisätaudit - Internal medicineCorrected qtArrhythmias CardiacHeartMiddle Aged020601 biomedical engineeringHealthy individualsCardiologyFemalelcsh:QTransfer entropy3111 Biomedicine030217 neurology & neurosurgeryScientific Reports
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Combined procedure for glaucoma and cataract: A retrospective study

1994

Abstract To ascertain the long-term effects of a triple procedure in the case of coexisting cataract and glaucoma, we did a retrospective study of 93 eyes that had cataract extraction, IOL implantation, and trabeculectomy within a ten-year period. Mean follow-up was 32.4 ± 21.9 months. Mean postoperative intraocular pressure (IOP) was significantly lower than preoperatively, even though fewer medications were being used. One year after surgery, 60% of eyes had a best corrected visual acuity of 20/40 or better with an average improvement of 3.8 Snellen lines. Patients who had had surgery four or more years before the study had the highest percentage of eyes with an IOP exceeding 22 mm Hg. Th…

AdultMaleIntraocular pressuremedicine.medical_specialtyAdolescentgenetic structuresmedicine.medical_treatmentEye diseaseVisual AcuityGlaucomaTrabeculectomyIntraocular lensCataract ExtractionOphthalmologymedicineHumansTrabeculectomyLongitudinal StudiesIntraocular PressureAgedRetrospective StudiesAged 80 and overLenses IntraocularBest corrected visual acuitybusiness.industryGlaucomaRetrospective cohort studyCombined procedureMiddle Agedmedicine.diseaseeye diseasesSensory SystemsSurgeryOphthalmologyTreatment OutcomeFemaleSurgerysense organsbusinessFollow-Up StudiesJournal of Cataract and Refractive Surgery
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Variability of reverse transcriptase and overlapping S gene in hepatitis B virus isolates from untreated and lamivudine-resistant chronic hepatitis B…

2009

Background The high degree of diversity of the hepatitis B virus (HBV) quasispecies in chronically infected individuals raises the possibility that HBV genetic variants favouring resistance to nucleoside/nucleotide analogues (NAs) might pre-exist to treatment. The aim of this study was to investigate the genetic variability of the entire HBV reverse transcriptase (RT) domain and of the overlapping S gene in a large series of untreated hepatitis B surface antigen carriers and in lamivudine (3TC)-resistant patients. Methods Sequencing analysis of the entire HBV RT domain of isolates from 100 untreated (treatment- naive group) and 59 3TC-resistant (3TC-resistant group) consecutive patients wit…

AdultMaleSettore MED/07 - Microbiologia E Microbiologia ClinicaHepatitis B virusAdult; Aged; Drug Resistance; Viral; Female; Genetic Variation; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B; Chronic; Humans; Lamivudine; Male; Middle Aged; Mutation; RNA-Directed DNA Polymerase; Reverse Transcriptase Inhibitors; Sequence Analysis; DNA; Treatment OutcomeDrug ResistanceViral quasispeciesmedicine.disease_causeVirusHepatitis B ChronicOrthohepadnavirusDrug Resistance ViralmedicineHumansPharmacology (medical)ViralChronicAgedPharmacologyHepatitis B virusSettore MED/12 - GastroenterologiaHepatitis B Surface AntigensbiologyReverse-transcriptase inhibitorLamivudineGenetic VariationRNA-Directed DNA PolymeraseSequence Analysis DNADNAMiddle Agedbiology.organism_classificationHepatitis BVirologyReverse transcriptaseInfectious DiseasesTreatment OutcomeHepadnaviridaeLamivudineMutationReverse Transcriptase InhibitorsHBV reverse transcriptase gene S lamivudine resistantFemaleSequence Analysismedicine.drug
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Mother- and father-infant interactions at 3 months of corrected age: The effect of severity of preterm birth

2017

Early interactions of 92 preterm infants with their mothers (n = 54) and fathers (n = 38) were explored at 3 months using CARE-Index. Results showed differences in interactions based on parent's gender, with higher control in mothers and unresponsiveness in fathers, while no effect of severity of birth weight emerged.

AdultMalemedicine.medical_specialtyBirth weightMothersDevelopmental psychologySettore M-PSI/04 - Psicologia Dello Sviluppo E Psicologia Dell'Educazione03 medical and health sciencesFathers0302 clinical medicineCorrected AgeFatherPregnancy030225 pediatricsDevelopmental and Educational PsychologyMedicineHumans0501 psychology and cognitive sciencesParent-Child RelationsEarly interactionMotherbusiness.industryObstetrics05 social sciencesInfantVLBWInfant BehaviorELBWPremature BirthFemalebusinessPrematurityInfant PrematureHumanParent-Child Relation050104 developmental & child psychology
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Testing Frequency-Domain Causality in Multivariate Time Series

2010

We introduce a new hypothesis-testing framework, based on surrogate data generation, to assess in the frequency domain, the concept of causality among multivariate (MV) time series. The approach extends the traditional Fourier transform (FT) method for generating surrogate data in a MV process and adapts it to the specific issue of causality. It generates causal FT (CFT) surrogates with FT modulus taken from the original series, and FT phase taken from a set of series with causal interactions set to zero over the direction of interest and preserved over all other directions. Two different zero-setting procedures, acting on the parameters of a MV autoregressive (MVAR) model fitted on the ori…

AdultMultivariate statisticsTime FactorsBiomedical EngineeringSurrogate datasymbols.namesakemultivariate autoregressive (MVAR) modeldirected coherence (DC)StatisticsHumansCoherence (signal processing)Computer SimulationEEGMathematicsSignal processingsurrogate dataFourier Analysispartial directed coherence (PDC)Models CardiovascularReproducibility of ResultsEstimatorElectroencephalographySignal Processing Computer-AssistedCardiovascular variabilityFourier transformAutoregressive modelFrequency domainMultivariate AnalysisSettore ING-INF/06 - Bioingegneria Elettronica E InformaticasymbolsAlgorithmAlgorithmsIEEE Transactions on Biomedical Engineering
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Impact of the line of sight on toric phakic intraocular lenses for hyperopia

2003

We present a hyperopic patient with a decentered line of sight in whom the residual refractive error after toric phakic intraocular lens (TP IOL) implantation was improved by displacement and individualized treatment. A 35-year-old woman presented with asthenopic complaints 2 months after bilateral TP IOL implantation and IOL rotation 4 weeks later. Examination revealed the line of sight to be nasally and inferiorly decentered in relation to the center of the pupil. A more nasal reenclavation of the TP IOL decreased the coma, and the uncorrected visual acuity was 20/20. We conclude that line of sight should be measured before TP IOL implantation, especially in hyperopic eyes.

AdultReoperationRefractive errormedicine.medical_specialtygenetic structuresEye diseasemedicine.medical_treatmentVision DisordersVisual AcuityComa (optics)Intraocular lensUncorrected visual acuityPhakic intraocular lensPupilVision disorderForeign-Body MigrationLens Implantation IntraocularOphthalmologyLens CrystallinemedicineHumansbusiness.industryAstigmatismCorneal TopographyPupilmedicine.diseaseeye diseasesSensory SystemsOphthalmologyHyperopiaOptometryFemaleSurgeryAsthenopiasense organsmedicine.symptombusinessJournal of Cataract and Refractive Surgery
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Inducible nitric oxide synthase in skeletal muscle of patients with chronic heart failure

1998

Abstract Objectives. The expression and localization of inducible nitric oxide (NO) synthase (NOS II) was evaluated as a source of NO which has been shown to affect muscle contraction. Background. Advanced stages of chronic heart failure are associated with systemic activation of cytokines which have been shown to stimulate the expression of NOS II in various cell types, including myocytes. We hypothesized that systemic cytokine activation could lead to expression of NOS II in skeletal muscle of patients with chronic heart failure. Methods. Skeletal muscle specimens were obtained by percutaneous needle biopsy in six normal volunteers and eight patients with heart failure (New York Heart Ass…

Adultmedicine.medical_specialtyHeart diseaseGene ExpressionNitric Oxide Synthase Type IIPolymerase Chain ReactionNitric oxidechemistry.chemical_compoundInternal medicineGene expressionmedicineHumansMyocyteRNA MessengerMicroscopy ImmunoelectronMuscle SkeletalHeart Failurebiologybusiness.industrySkeletal muscleRNA-Directed DNA PolymeraseMiddle Agedmedicine.diseaseNitric oxide synthaseEndocrinologymedicine.anatomical_structurechemistryHeart failureChronic Diseasebiology.proteinNitric Oxide Synthasemedicine.symptombusinessCardiology and Cardiovascular MedicineMuscle contractionJournal of the American College of Cardiology
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Quantifying the contribution of arm postural tremor to the outcome of goal-directed pointing task by displacement measures.

2004

A method for quantifying the outcome of goal-directed postural pointing was presented and used for relating the tremor output to the oscillations of single arm landmarks. The displacement of reflective markers placed on shoulder, upper arm, forearm, and hand were measured by an optoelectronic motion capture system in nine subjects holding a laser penlight pointed at a target. The high signal-to-noise ratio of the measured displacement series (from 7:1 for shoulder marker to 30:1 for hand marker) demonstrated the feasibility of the proposed system to carry out tremor analysis. The track of the laser emission on the target, reconstructed from penlight displacements, was studied as the outcome…

Adultmedicine.medical_specialtyMovementPhysiological tremor; Motor control; Goal-directed pointing; Human movement analysis; Spectral analysisSpectral analysisMotion captureHuman movement analysisTask (project management)Spectral analysiPhysical medicine and rehabilitationForearmControl theoryMotor controlTremormedicineHumansDisplacement (orthopedic surgery)PhysicsAnalysis of VarianceNeuroscience (all)General NeuroscienceTrack (disk drive)Motor controlPostural tremorPhysiological tremormedicine.anatomical_structureHuman movement analysiArmLow-frequency oscillationPhotic StimulationPsychomotor PerformanceGoal-directed pointing
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Na+ ions binding to the bradykinin B2 receptor suppress agonist-independent receptor activation.

1996

Control of the balance between receptor activation and inactivation is a prerequisite for seven transmembrane domain (7TM) receptor function. We asked for a mechanism to stabilize the inactive receptor conformation which prevents agonist-independent receptor activation. Na+ ions have reciprocal effects on agonist versus antagonist interaction with various 7TM receptors. To investigate the Na+ dependence of receptor activation we chose the bradykinin B2 receptor as a prototypic 7TM receptor. Decrease of the intracellular Na+ content from 40 mM to 10 mM of COS-1 cells transiently expressing rat B2 receptors activated the B2 receptor in the absence of agonist as shown by a 3-fold increase in t…

AgonistIntracellular FluidIntrinsic activityReceptor Bradykinin B2medicine.drug_classInositol PhosphatesBradykininIn Vitro TechniquesBradykininLigandsBiochemistryCell Linechemistry.chemical_compoundmedicineAnimalsHumansPoint MutationBradykinin receptorPhosphorylationReceptorG protein-coupled receptorReceptors BradykininSodiumRatschemistryCOS CellsBiophysicsMutagenesis Site-DirectedAlpha-4 beta-2 nicotinic receptorIntracellularBiochemistry
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Geometric interpretation of the optimality conditions in multifacility location and applications

1991

Geometrical optimality conditions are developed for the minisum multifacility location problem involving any norm. These conditions are then used to derive sufficient conditions for coincidence of facilities at optimality; an example is given to show that these coincidence conditions seem difficult to generalize.

AlgebraControl and OptimizationApplied MathematicsNorm (mathematics)Theory of computationCalculusGraph theoryDirected graphManagement Science and Operations ResearchCoincidenceMathematicsJournal of Optimization Theory and Applications
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