Search results for "reduction"

Expanding the protein catalogue in the proteome reference map of human breast cancer cells

2006

In this report we present a catalogue of 162 proteins (including isoforms and variants) identified in a prototype of proteomic map of breast cancer cells. This work represents the prosecution of previous studies describing the protein complement of breast cancer cells of the line 8701-BC, which has been well characterized for several parameters, providing to be a useful model for the study of breast cancer-associated candidate biomarkers. In particular, 110 spots were identified ex novo by PMF, or validated following previous gel matching identification method; 30 were identified by N-terminal microsequencing and the remaining by gel matching with maps available from our former work. As a c…

Saccharomyces cerevisiae Cytosolic Thioredoxins Control Glycolysis, Lipid Metabolism, and Protein Biosynthesis under Wine-Making Conditions.

2019

Thioredoxins are small proteins that regulate the cellular redox state, prevent oxidative damage, and play an active role in cell repair. Oxidative stress has proven to be of much relevance in biotechnological processes when the metabolism of Saccharomyces cerevisiae is mainly respiratory. During wine yeast starter production, active dry yeast cytosolic thioredoxin Trx2p is a key player in protecting metabolic enzymes from being oxidized by carbonylation. Less is known about the role of redox control during grape juice fermentation. A mutant strain that lacked both cytosolic thioredoxins, Trx1p and Trx2p, was tested for grape juice fermentation. Its growth and sugar consumption were greatly…

A numerical approach to the voltammograms of the reduction of Prussian Blue films on ITO electrodes

1997

The uncompensated resistance, mainly due to the ITO electrode, modifies the shape of voltammetric curves of the system Prussian Blue ⇄ Everitt's Salt films deposited on this transparent electrode. A numerical finite difference model which is able to explain the shape of these voltammetric curves is studied in this paper. This model explains the dependence of voltammetric curves on the film thickness and uncompensated resistance.

Response und Remission in der Psychotherapieforschung

2010

Treatment effects of psychotherapy are usually studied using analysis of mean differences, tests of significance and effect size measures. These strategies, however, do not answer the question of how large the proportion of patients is who responded to treatment or who even reached remission. This article compares 2 competing methods of response and remission analysis: The Reliable Change Index (RCI) according to Jacobson et al. and the method of percent symptom reduction (PSR). We applied both methods using a sample of 338 patients with DSM-IV major depressive disorder. A pre-post treatment effect of Cohen's d=1,16 (intention-to-treat) resulted for the Beck Depression Inventory (BDI), corr…

Informal Disaster Governance

2020

<p>Scholars and practitioners are increasingly questioning formal disaster governance (FDG) approaches as being too rigid, slow, and command-and-control driven. Too often, local realities and non-formal influences are sidelined or ignored to the extent that disaster governance can be harmed through the efforts to impose formal and/or political structures. A contrasting narrative emphasises so-called bottom-up, local, and/or participatory approaches which this article proposes to encapsulate as Informal Disaster Governance (IDG). This article theorises IDG and situates it within the long-standing albeit limited literature on the topic, paying particular attention to the literature’s fa…

Lung cancer survival in Germany: A population-based analysis of 132,612 lung cancer patients.

2014

Lung cancer is the most common cancer-related death worldwide. In Germany it accounts for 25% of cancer deaths in men, and 14% in women. The aim of this study is to provide an overview of 5-year relative survival by sex, age, histology, and tumour stage in Germany representing a population of 26.7 million people.The study is based on a pooled German dataset including data from 12 population-based cancer registries covering around one third of the German population. A total of 132,612 patients diagnosed with lung cancer from 2002 to 2010 were included in the analysis. Survival estimates for the time period 2007-2010 were calculated using period analysis. Differences in survival between sexes…

P-146 * PROLONGED SURVIVAL AND REDUCED HOSPITAL STAY AFTER VIDEO-ASSISTED THORACOSCOPIC SURGERY SEGMENTECTOMY FOR SMALL LUNG CARCINOMA

2014

OA12.05 Imaging-Guided Target Volume Reduction in Radiotherapy of Lung Cancer: The Prospective Randomized Multinational PET-Plan Trial

2019

Material and Technology: Back to the Future for the Choice of Interface for Non-Invasive Ventilation – A Concise Review

2020

Non-invasive ventilation (NIV) has dramatically changed the treatment of both acute and chronic respiratory failure in the last 2 decades. The success of NIV is correlated to the application of the “best ingredients” of a patient’s “tailored recipe,” including the appropriate choice of the selected candidate, the ventilator setting, the interface, the expertise of the team, and the education of the caregiver. The choice of the interface is crucial for the success of NIV. Type (oral, nasal, nasal pillows, oronasal, hybrid mask, helmet), size, design, material and headgears may affect the patient’s comfort with respect to many aspects, such as air leaks, claustrophobia, skin erythema, eye irr…

Sleep apnoea and metabolic dysfunction.

2013

Obstructive sleep apnoea (OSA) is a highly prevalent condition often associated with central obesity. In the past few years, several studies have analysed the potential independent contribution of OSA to the pathogenesis of metabolic abnormalities, including type 2 diabetes, the metabolic syndrome and non-alcoholic fatty liver disease. New perspectives in OSA patient care have been opened by the promotion of lifestyle interventions, such as diet and exercise programmes that could improve both OSA and the metabolic profile. The rich clinical literature on this subject, together with the growing amount of data on pathophysiological mechanisms provided by animal studies using the chronic inter…