Search results for "reduction"

showing 10 items of 2058 documents

Study of chemical changes produced in virgin olive oils with different phenolic contents during an accelerated storage treatment.

2009

Chemical changes produced in an extra virgin olive oil sample in the presence (EVOO) and absence (EVOOP) of its phenolic fraction during an accelerated storage treatment at 60 degrees C up to 7 weeks were studied. Modifications in phenol content, as well as changes in several quality parameters (free acidity, peroxide value, UV absorbance, fatty acid composition, oxidative stability index, and tocopherol content) were also evaluated under the same storage conditions and compared to those of the same sample deprived of phenolic compounds. When the phenolic extract of the EVOO was studied, a decrease of the antioxidants first present in the sample and an increase of the oxidized products were…

Food storageTocopherolsVIRGIN OLIVE OILOXIDATIONAGINGchemistry.chemical_compoundPhenolsFood PreservationPhenolPlant OilsPhenolsPeroxide valueTocopherolChemical compositionOlive OilChromatography High Pressure LiquidChromatographyFatty AcidsFood preservationGeneral ChemistryHydrogen-Ion ConcentrationVegetable oilchemistryHPLCPHENOLIC COMPOUNDSGeneral Agricultural and Biological SciencesOxidation-ReductionJournal of agricultural and food chemistry
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The Reduction Pathway of End-on Coordinated Dinitrogen. II. Electronic Structure and Reactivity of Mo/W−N2, −NNH, and −NNH2 Complexes

2001

DFT calculations (B3LYP/LanL2DZ) of simplified models of [Mo(N(2))(2)(dppe)(2)] and the two protonated derivatives [MoF(NNH)(dppe)(2)] and [MoF(NNH(2))(dppe)(2)](+) (dppe = 1,2-bis(diphenylphosphino)ethane) provide quantitative insight into the reduction and protonation of dinitrogen bound end-on terminally to transition metals. This "asymmetric" reduction pathway is characterized by a stepwise increase of covalency and a concomitant charge donation from the metal center during each protonation reaction. The major part of metal-to-ligand charge transfer occurs after the first protonation leading to coordinated diazenido(-). In contrast, addition of the second proton is accompanied by a mino…

Force constantProtonChemistryProtonationElectronic structureInorganic ChemistryMetalReduction (complexity)CrystallographyTransition metalComputational chemistryvisual_artvisual_art.visual_art_mediumReactivity (chemistry)Physical and Theoretical ChemistryInorganic Chemistry
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Struktur-Wirkungs-Beziehungen bei Histaminanaloga, 13. Mitt.: 5(4)-Cyclisch substituierte Histamine und Nα-Methyl-histamine

1976

Es wird die Darstellung von 5(4)-cyclisch substituierten Histaminen und Nα-Methyl-histaminen durch Cyclisierung von 1-aryl-substituierten 2-Brom-4-phthalimido-butan-1-onen mit Formamid oder Benzamidin und anschliesende Hydrolyse bzw. Reduktion der Zwischenprodukte beschrieben. C-5(4) Cyclic Substituted Histamines and Nα-Methylhistamines The preparation of C-5(4) cyclic substituted histamines and Nα-methylhistamines by cyclisation of 1-aryl-2-bromo-4-phthalimidobutan-1-ones with formamide or benzamidine, followed by hydrolysis or reduction of the intermediates, is described.

Formamidechemistry.chemical_compoundHydrolysisChemistryDrug DiscoveryPharmaceutical ScienceOxidation reductionMedicinal chemistryHistamineBenzamidineArchiv der Pharmazie
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Iodide-Photocatalyzed Reduction of Carbon Dioxide to Formic Acid with Thiols and Hydrogen Sulfide.

2016

The photolysis of iodide anions promotes the reaction of carbon dioxide with hydrogen sulfide or thiols to quantitatively yield formic acid and sulfur or disulfides. The reaction proceeds in acetonitrile and aqueous solutions, at atmospheric pressure and room temperature by irradiation using a low-pressure mercury lamp. This transition-metal-free photocatalytic process for CO2 capture coupled with H2 S removal may have been relevant as a prebiotic carbon dioxide fixation.

FormatesFormic acidGeneral Chemical EngineeringHydrogen sulfideInorganic chemistryIodidechemistry.chemical_element010402 general chemistryIodine01 natural sciencesCatalysisCatalysisReaccions químiqueschemistry.chemical_compoundEnvironmental ChemistryGeneral Materials ScienceHydrogen SulfideSulfhydryl Compoundschemistry.chemical_classification010405 organic chemistryCarbon fixationCarbon DioxideIodidesPhotochemical ProcessesSulfur0104 chemical sciencesGeneral EnergychemistryCarbon dioxideQuímica orgànicaOxidation-ReductionChemSusChem
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Ammonium formate-Pd/C as a new reducing system for 1,2,4-oxadiazoles. Synthesis of guanidine derivatives and reductive rearrangement to quinazolin-4-…

2021

1,2,4-Oxadiazole is a heterocycle with wide reactivity and many useful applications. The reactive O-N bond is usually reduced using molecular hydrogen to obtain amidine derivatives. NH4CO2H-Pd/C is here demonstrated as a new system for the O-N reduction, allowing us to obtain differently substituted acylamidine, acylguanidine and diacylguanidine derivatives. The proposed system is also effective for the achievement of a reductive rearrangement of 5-(2′-aminophenyl)-1,2,4-oxadiazoles into 1-alkylquinazolin-4(1H)-ones. The alkaloid glycosine was also obtained with this method. The obtained compounds were preliminarily tested for their biological activity in terms of their cytotoxicity, induce…

Formatesquinazolin-4-onemedicine.disease_causeGuanidineschemistry.chemical_compoundBiology (General)CytotoxicityAmmonium formateSpectroscopyOxadiazolesMolecular StructureChemistryAlkaloidBiological activityGeneral MedicineComputer Science ApplicationsChemistryOxidation-ReductionPalladiumCell SurvivalQH301-705.5Dipeptidyl Peptidase 4chemistry.chemical_elementAntineoplastic AgentsreductionArticleCatalysisInorganic ChemistryAmidine4-oxadiazolereduction;Cell Line TumorDiabetes MellitusAmmonium formatemedicineHumansHypoglycemic AgentsReactivity (chemistry)Physical and Theoretical ChemistryMolecular BiologyQD1-999QuinazolinonesSettore MED/04 - Patologia GeneralediacylguanidineOrganic Chemistry124-oxadiazolealpha-GlucosidasesacylguanidineSettore CHIM/06 - Chimica OrganicapalladiumCombinatorial chemistryModels ChemicalA549 CellsOxidative stress
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Squaramide-based reagent for selective chromogenic sensing of Cu(II) through a zwitterion radical.

2010

A minimalist squaramide-based chemodosimeter for Cu(2+) is described. Upon selective chelation to 2, Cu(2+) induces the formation of a highly colored zwitterionic radical, which is kinetically stable for hours. The presence of a radical is confirmed by EPR and ESI-MS. It is then possible to use reagent 2 for visual and selective sensing of Cu(2+) at neutral pH.

Free RadicalsChemistryChromogenicOrganic ChemistrySquaramideElectron Spin Resonance SpectroscopyWaterHydrogen-Ion ConcentrationPhotochemistryBiochemistryAmideslaw.inventionchemistry.chemical_compoundlawZwitterionReagentChelationPhysical and Theoretical ChemistryNeutral phElectron paramagnetic resonanceOxidation-ReductionCopperCyclobutanesChelating AgentsOrganic letters
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Denoising of MR spectroscopy signals using total variation and iterative Gauss-Seidel gradient updates

2015

We present a fast variational approach for denoising signals from magnetic resonance spectroscopy (MRS). Differently from the TV approaches applied to denoising of images, this is the first time to our knowledge that it has been used for the processing of free induction decay signals from single-voxel spectroscopy (SVS) acquisitions. Another novelty in this study is the direct use of the Euler Lagrange formulation coupled with Gauss Seidel gradient updates to improve the speed of iteration and reduce ringing. Results from brain MRS signals show improvement in signal to noise ratio as well as reduction in estimation error in the quantification of metabolites.

Free induction decayReduction (complexity)Mathematical optimizationSignal-to-noise ratioNoise reductionGauss–Seidel methodRingingTotal variation denoisingSpectroscopyAlgorithmMathematics2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)
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Functional principal component analysis for multivariate multidimensional environmental data

2015

Data with spatio-temporal structure can arise in many contexts, therefore a considerable interest in modelling these data has been generated, but the complexity of spatio-temporal models, together with the size of the dataset, results in a challenging task. The modelization is even more complex in presence of multivariate data. Since some modelling problems are more natural to think through in functional terms, even if only a finite number of observations is available, treating the data as functional can be useful (Berrendero et al. in Comput Stat Data Anal 55:2619–2634, 2011). Although in Ramsay and Silverman (Functional data analysis, 2nd edn. Springer, New York, 2005) the case of multiva…

Functional principal component analysisStatistics and ProbabilityMultivariate statistics2300GeneralizationDimensionality reductionGeneralized additive modelFunctional data analysisFunctional principal component analysiContext (language use)computer.software_genreMultivariate spatio-temporal dataCovariateP-splineData miningStatistics Probability and UncertaintycomputerSmoothingGeneral Environmental ScienceMathematics
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A chemical approach for the reduction of beauvericin in a solution model and in food systems.

2014

Abstract Beauvericin (BEA) is a bioactive compound produced by the secondary metabolism of several Fusarium strains with a strong antibacterial, antifungal, and insecticidal activities. This study evaluated the reduction of BEA added at 25 mg/kg in phosphate buffer saline (PBS) solutions at pH of 4, 7 and 10, or to different cereal products (kernels and flours) by the bioactive compounds phenyl isothiocyanate (PITC) and benzyl isothiocyanate (BITC). The concentration of the mycotoxin was evaluated using liquid chromatography coupled to the diode array detector (LC-DAD). In solution, BEA reduction ranged from 9% to 94% on a time-dependent fashion and lower pH levels resulted in higher BEA re…

FusariumChromatographybiologyBenzyl isothiocyanatePhenyl isothiocyanatefood and beveragesFood ContaminationGeneral MedicineModels TheoreticalToxicologybiology.organism_classificationBeauvericinBioactive compoundchemistry.chemical_compoundchemistryChromatography detectorDepsipeptidesSecondary metabolismMycotoxinOxidation-ReductionFood ScienceChromatography LiquidFood and chemical toxicology : an international journal published for the British Industrial Biological Research Association
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Beauvericin-induced cytotoxicity via ROS production and mitochondrial damage in Caco-2 cells.

2013

The cytotoxicity of beauvericin (BEA) on human colon adenocarcinoma (Caco-2) cells was studied as a function of time. Moreover, the oxidative damage and cell death endpoints were monitored after 24, 48 and 72 h. After BEA exposure, the IC₅₀ values ranged from 1.9 ± 0.7 to 20.6 ± 6.9 μM. A decrease in reduced glutathione (GSH; 31%) levels, as well as an increase in oxidized glutathione (GSSG, 20%) was observed. In the presence of BEA, reactive oxygen species (ROS) level was highly increased at an early stage with the highest production of 2.0-fold higher than the control that was observed at 120 min. BEA induced cell death by mitochondria-dependent apoptotic process with loss of the mitochon…

G2 PhaseProgrammed cell deathDNA damageCell SurvivalApoptosisBiologyToxicologymedicine.disease_causechemistry.chemical_compoundInhibitory Concentration 50NecrosisDepsipeptidesmedicineHumansIntestinal Mucosachemistry.chemical_classificationMembrane Potential MitochondrialReactive oxygen speciesIonophoresCell growthGeneral MedicineGlutathioneMycotoxinsMolecular biologyGlutathioneBeauvericinCell biologyMitochondriaKineticsOxidative StresschemistryApoptosisLipid PeroxidationCaco-2 CellsReactive Oxygen SpeciesOxidation-ReductionOxidative stressDNA DamageToxicology letters
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