Search results for "refractive error"

showing 10 items of 125 documents

OCT for Assessing Artificial Tears Effectiveness in Contact Lens Wearers

2011

PURPOSE: To apply a commercially available high-resolution spectral domain optical coherence tomographer (SOCT) to assess the change in tear volume after application of a new artificial tears formulation specifically developed for contact lens (CL) users. METHODS: Twenty OD from young healthy CL wearers (mean age, 24.7 ± 3.5 years) with refractive errors ranging from -0.75 to -2.50 D (mean, -1.56 ± 0.69 D) were examined. All subjects were fitted with Focus Dailies CL (Ciba Vision), and two drops of Blink Contacts (AMO), lubricating formulation specifically developed for CL wearers, were instilled after baseline measures. Tear meniscus volume (TMV) was measured immediately after and 1 min, 1…

Adultmedicine.medical_specialtyContact Lensesmedicine.medical_treatmentMeniscus (anatomy)Tear volumeYoung AdultRegular distributionOphthalmologyImage Processing Computer-AssistedHumansMedicinebusiness.industryRepeated measures designContact Lenses HydrophilicRefractive ErrorsContact lensOphthalmologyArtificial tearsmedicine.anatomical_structureTear meniscusOftalmologíaDry Eye SyndromesEyelidOphthalmic SolutionsbusinessTomography Optical CoherenceFollow-Up StudiesOptometryOptometry and Vision Science
researchProduct

Prevalence of general binocular dysfunctions in a population of university students.

1997

Although some authors report that the prevalence of general binocular dysfunctions (nonstrabismic) for nonpresbyopes in the clinical population is greater than any condition except refractive error, limited research is available to support this statement. This clinical study determined the presence and clinical implications of these conditions in a population of university students with heavy near visual demands.From a group of second year students who were given a thorough eye examination, 65 students were selected. The criteria for selection were the absence of significant uncorrected refractive error, healthy eyes, and no strabismus or amblyopia.32.3% of the subjects showed general binoc…

Adultmedicine.medical_specialtyRefractive errorConvergence insufficiencyUniversitiesAccommodative insufficiencyPopulationVision DisordersClinical studyEpidemiologymedicinePrevalenceHumanseducationStudentseducation.field_of_studyVision Binocularbusiness.industryAccommodation OcularConvergence Ocularmedicine.diseaseOphthalmologySpainOptometrybusinessPsychologyAccommodationBinocular visionOptometryClinical psychologyOptometry and vision science : official publication of the American Academy of Optometry
researchProduct

Femtosecond laser versus mechanical keratome LASIK for myopia.

2005

To assess efficacy, safety, predictability, stability, and changes in corneal higher-order aberrations (CHOAs) and contrast sensitivity (CS) after a femtosecond laser for LASIK and standard LASIK for myopia.Prospective, randomized, comparative clinical study.Two hundred eyes of 100 consecutive patients who underwent LASIK treatment using the VISX S2 laser system. A femtosecond laser for flap creation was used in 100 eyes (50 patients; spherical equivalent [SE], -2.85+/-1.79 diopters [D]), and a mechanical microkeratome was used in 100 eyes (50 patients; SE, -2.90+/-1.63 D).Uncorrected visual acuity (UCVA), best spectacle-corrected visual acuity (BSCVA), manifest refraction, CS by means of t…

Adultmedicine.medical_specialtyRefractive errorVisual acuitygenetic structuresmedicine.medical_treatmentKeratomileusis Laser In SituVisual AcuityKeratomileusisSurgical FlapsContrast SensitivityCorneaTonometry OcularMicrokeratomemedicineMyopiaHumansProspective StudiesDioptremedicine.diagnostic_testbusiness.industryLasersLASIKCorneal Topographymedicine.diseaseCorneal topographyeye diseasesPhotorefractive keratectomySurgeryOphthalmologyTreatment Outcomesense organsmedicine.symptombusinessOphthalmology
researchProduct

The effect of simulated normal and amblyopic higher-order aberrations on visual performance.

2012

Purpose To study the effect of simulated amblyopic and normal higher-order aberrations on visual performance of normal eyes. Methods To assess visual function, an adaptive optics visual simulator was used to compensate volunteers' ocular aberrations and simulate the wavefront aberration patterns found in healthy and amblyopic eyes in 7 healthy individuals. Visual acuity for high (100%), medium (50%), and low (10%) contrast and contrast sensitivity at 10, 20, and 25 cycles per degree (cpd) were measured after simulation of both pattern aberrations. The modulation transfer function and the point spread function were computed based on the aberration data. All measures were taken for 3 and 5.5 …

Adultmedicine.medical_specialtyVisual acuityCorneal Wavefront Aberrationgenetic structuresmedia_common.quotation_subjectVisual AcuityAmblyopiaPupilContrast SensitivityYoung AdultOphthalmologyOptical transfer functionmedicineContrast (vision)Humansmedia_commonContrast levelbusiness.industryAberrometryPupil sizeAstigmatismPupilModels TheoreticalRefractive Errorseye diseasesOphthalmologyAberrations of the eyePediatrics Perinatology and Child HealthOptometrysense organsSpatial frequencymedicine.symptombusinessJournal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
researchProduct

Contrast sensitivity after LASIK flap creation with a femtosecond laser and a mechanical microkeratome

2007

ABSTRACT PURPOSE: To compare the effects on contrast sensitivity of the IntraLase femtosecond laser for flap creation (IntraLASIK) and standard LASIK for myopia. METHODS: Two hundred eyes of 100 consecutive patients underwent LASIK treatment using the VISX S2 laser system. The femtosecond laser (15 kHz IntraLase) was used for flap creation in 100 eyes (50 patients) and a mechanical microkeratome (Carriazo-Barraquer) was used in 100 eyes (50 patients). Best spectacle-corrected contrast sensitivity was measured before and 6 months postoperatively in the IntraLASIK and mechanical LASIK groups. The IntraLASIK and mechanical LASIKinduced changes in contrast sensitivity were compared under photop…

Adultmedicine.medical_specialtygenetic structuresMesopic visionmedicine.medical_treatmentmedia_common.quotation_subjectKeratomileusis Laser In SituSurgical Flapslaw.inventionContrast SensitivitylawMicrokeratomeOphthalmologymedicineHumansContrast (vision)media_commonbusiness.industryLASIKEquipment DesignRefractive ErrorsLasereye diseasesRefractive Surgical ProceduresSurgeryOphthalmologyTreatment OutcomeFemtosecondSurgerysense organsbusinessSensitivity (electronics)Follow-Up StudiesPhotopic vision
researchProduct

Central corneal thickness in mucopolysaccharidosis II and VI.

2010

Objective To describe the ultrasonographically detected central corneal thickness (CCT) in patients with Type II and VI mucopolysaccharidosis (MPS) and its impact on applanation tonometry and glaucoma detection. Methods Twenty-eight patients with MPS (19 MPS II, nine MPS VI) underwent pachymetric investigation of CCT. Additionally, ultrasound measurements of axial length of the globe, slit-lamp evaluation with semiquantitative grading of corneal clouding, applanation tonometry, and assessment of refractive error were performed. Results Median average corneal thickness was 534.5 microm (range, 491.5-579.0 microm) in the MPS II and 547.0 microm (range, 492.5-693.05 microm) in the MPS VI group…

Applanation tonometryAdultMalecongenital hereditary and neonatal diseases and abnormalitiesRefractive errorIntraocular pressuremedicine.medical_specialtygenetic structuresAdolescentMucopolysaccharidosis IIMucopolysaccharidosisGlaucomaCorneal DiseasesCorneaTonometry OcularOphthalmologymedicineHumansIn patientProspective StudiesChildIntraocular PressureMucopolysaccharidosis IIUltrasonographyMucopolysaccharidosis VIAnthropometrybusiness.industryUltrasoundnutritional and metabolic diseasesGlaucomaMiddle Agedmedicine.diseaseeye diseasesOphthalmologyFemalesense organsbusinessCornea
researchProduct

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

2013

Author version made available in accordance with the publisher's policy.

Candidate geneRefractive errorBone Morphogenetic Protein 2Genome-wide association studyVARIANTSGenomeGenome-wide association studies0302 clinical medicineRisk FactorsMyopiaGRIA4Genetics0303 health sciencesKCNQ Potassium ChannelsDisease geneticsEYE GROWTHASSOCIATIONRETINAL-PIGMENT EPITHELIUMRefractive ErrorsGenetic load3. Good healthADAPTED MOUSE RETINAMeta-analysisACIDPOTASSIUM CHANNELEXPRESSIONSingle-nucleotide polymorphismBiologyWhite PeopleArticle03 medical and health sciencesAsian PeoplemedicineGeneticsHumansGenetic Predisposition to DiseaseReceptors AMPAgene; myopia; refractive030304 developmental biologyHomeodomain Proteinsta1184ta3121medicine.diseaseGENEAlcohol OxidoreductasesSERINE-PROTEASEbiology.protein030221 ophthalmology & optometrySusceptibility locusTrans-ActivatorsEye disorderLamininSerine ProteasesGWAS; meta-analyses; refractive error; myopiaGenome-Wide Association StudyNature Genetics
researchProduct

Repeatability of in vitro power profile measurements for multifocal contact lenses

2015

Abstract Purpose To evaluate the repeatability of an optical device (NIMO TR1504, Lambda-X, Belgium) for measuring multifocal contact lens power profiles. Methods The NIMO TR1504 was used to measure power profiles 30 times for each of 10 different contact lenses from 4 major companies. All contact lenses were labelled as −3 D for distance vision; half were for high addition and half for low addition. The optical zone in all measurements was set to 3-mm radius. For each lens, the median power profile and the residuals of the 30 measurements were calculated. The 95% confidence bands and two indices that summarize measurement errors were calculated: the repeatability limit and an index of repe…

Contact lens powerObservational errorMaterials sciencegenetic structuresContact Lensesbusiness.industryReproducibility of ResultsEquipment DesignGeneral MedicineRepeatabilityRadiusRefraction OcularRefractive Errorseye diseaseslaw.inventionPower (physics)Lens (optics)OphthalmologyOpticslawHomogeneousHumanssense organsbusinessOptometryContact Lens and Anterior Eye
researchProduct

Axial Length and Anterior Segment Alterations in Former Preterm Infants and Full-Term Neonates Analyzed With Scheimpflug Imaging.

2017

Purpose To compare the axial length and anterior segment alterations in preterm infants with and without retinopathy of prematurity with those of full-term infants. Methods The Wiesbaden Prematurity Study investigated 503 participants of former gestational age ≤32 weeks and gestational age ≥37 weeks now being aged 4 to 10 years. This study included 485 participants in the prospective controlled cross-sectional, hospital-based study with successful Pentacam Scheimpflug imaging. Anterior segment parameters, axial length measurements, and associated factors were analyzed. Results Corneal thickness did not differ between former preterm and full-term infants. Significant differences were found b…

Diagnostic ImagingMalePediatricsmedicine.medical_specialtyCorneal PachymetryTerm BirthBirth weightVisual AcuityGestational AgeAstigmatismRefraction Ocular03 medical and health sciences0302 clinical medicineAnterior Eye SegmentMedicineBirth WeightHumansProspective StudiesCorneal pachymetryChildFull Termmedicine.diagnostic_testbusiness.industryGestational ageRetinopathy of prematurityInfant Low Birth Weightmedicine.diseaseRefractive ErrorsOphthalmologyLow birth weightAxial Length EyeCross-Sectional Studies030221 ophthalmology & optometryTerm BirthFemalemedicine.symptombusiness030217 neurology & neurosurgeryInfant PrematureCornea
researchProduct

2017

Purpose To analyze the effect of birth weight on ocular morphology, refraction and visual function in early adolescents aged 12–15 years. Material and methods We conducted a secondary data analysis using the public use files from the National Health and Nutrition Examination Survey of the period from 1999 to 2008. Study participants aged 12 to 15 years were included with data on birth weight and ophthalmic parameters including presenting distance visual acuity, objective refraction and keratometry. Visual acuity, sphere, astigmatism in power vectors J0 and J45, corneal power and corneal astigmatism were evaluated for an association with birth weight. Linear and logistic regression with adju…

GerontologyPediatricsmedicine.medical_specialtyUnivariate analysisRefractive errorMultidisciplinaryVisual acuitygenetic structuresNational Health and Nutrition Examination SurveyKeratometerbusiness.industryBirth weightAstigmatismmedicine.diseaseLogistic regressioneye diseaseslaw.invention03 medical and health sciences0302 clinical medicinelaw030225 pediatrics030221 ophthalmology & optometrymedicinemedicine.symptombusinessPLOS ONE
researchProduct