Search results for "regime"
showing 10 items of 750 documents
Output Field-Quadrature Measurements and Squeezing in Ultrastrong Cavity-QED
2015
We study the squeezing of output quadratures of an electro-magnetic field escaping from a resonator coupled to a general quantum system with arbitrary interaction strengths. The generalized theoretical analysis of output squeezing proposed here is valid for all the interaction regimes of cavity-quantum electrodynamics: from the weak to the strong, ultrastrong, and deep coupling regimes. For coupling rates comparable or larger then the cavity resonance frequency, the standard input–output theory for optical cavities fails to calculate the variance of output field-quadratures and predicts a non-negligible amount of output squeezing, even if the system is in its ground state. Here we show that…
Targeted Therapies for Colorectal Cancer
2015
In the last decades, the standard chemotherapeutic approach for the metastatic colorectal cancer (mCRC) treatment was represented by a 5-FU-based regimen with the addition of either oxaliplatin or irinotecan. Recent discoveries in the molecular biology field led to the spread of so-called targeted agents whose mechanism of action is based on the binding with specific target molecules (cellular receptors or soluble proteins) responsible for the activation of many transduction pathways required for malignant cell growth and survival. Among these, the most important consist of monoclonal antibodies (mAbs) and the tyrosine kinase inhibitors (TKIs). As a consequence, the different mechanism of a…
Effects of irrigation on fruit ripening behavior and metabolic changes in olive
2012
Olive (Olea europaea, cv Leccino) fruits grown under different water regimes were analyzed by metabolomics and specific transcript accumulation analyses. The fruit from non-irrigated (rain-fed) and irrigated trees cultivated under field conditions, with a seasonal water amount equivalent to the calculated crop evapotranspiration (ETc) was compared in the last developmental phase and, in particular, at commercial harvest. Metabolomics (GC-MS) analysis identified several hundred metabolites in ripe mesocarp, 46 of which showed significantly different contents in the rain-fed and irrigated samples. Some compounds involved in primary metabolism (carbohydrates, amino acids, organic acids) and se…
A 1-year maintenance after early adjuvant intravesical chemotherapy has a limited efficacy in preventing recurrence of intermediate risk non-muscle-i…
2010
Study Type – Therapy (RCT) Level of Evidence 1b OBJECTIVE To evaluate the efficacy of 1-year maintenance after a 6-week cycle of early intravesical chemotherapy, as the role of maintenance in intravesical chemotherapy is debated. PATIENTS AND METHODS Between May 2002 and August 2003, 577 patients with non-muscle-invasive bladder cancer (NMI-BC) underwent transurethral resection (TUR) and early intravesical chemotherapy (epirubicin, 80 mg/50 mL). They were randomized between a 6-week induction cycle and the induction cycle plus maintenance with 10 monthly instillations. In all, 95 patients with T1G3, Tis or single and primary Ta–T1 G1–G2 tumours were excluded; 482 patients at intermediate ri…
Spazi aperti di comunità in ambito climatico Mediterraneo. Il caso di Hassan Fathy in Egitto
2022
The complexity of the relationship between architecture and the Mediterranean climate, in energy regimes and resource scarcity, requires special attention. Specifically, the article aims to explore how community spaces can become design subjects, intervening in climatic, environmental, social, and cultural features. Hassan Fathy’s architecture, in particular the two schools in New Gourna and Fares, offer a different key to understanding man, climate, culture, technology, and education. A relationship that is still evolving today, calling architecture back toits educational and social focus.
Autoantibody Inhibitor Eradication In Acquired Hemophilia Associated with Cancer: a Retrospective Analysis
2010
Abstract Abstract 1418 Introduction: Acquired hemophilia (AH), a rare autoimmune disorder primarily of adults, is typically characterized by the presence of IgG oligoclonal antibodies to the clotting factor VIII protein (FVIII). About 10–15% of patients with AH have an underlying malignancy, but the etiologic relationship of cancer to formation of FVIII inhibitor is yet to be determined. To date, there have been no published, comprehensive reviews on the efficacy of various treatments for AH in the context of either solid tumor or hematologic malignancies. Therefore, we have systematically reviewed 86 patients with cancer-associated AH from our own cancer center and from the published liter…
Thermal diffusion and Soret feedback of gold-doped polyorganosiloxane nanospheres in toluene
2000
We have investigated diffusion and thermal diffusion properties of light-absorbing colloidal polyorganosiloxane microgels containing tiny nanometer-sized gold clusters dispersed in toluene. Transient holographic gratings allow for very subtle perturbations in the linear regime where Soret feedback is negligible. Gold-doped colloids of different size and crosslink ratios show different Soret coefficients but identical thermal diffusion coefficients D(T). Undoped colloids tend to aggregate, but a consistent interpretation is obtained if an identical D(T) is assumed for the doped, the undoped, and the aggregated particles. Previously reported Soret feedback measurements on similar systems inci…
Depletion of coastal predatory fish sub-stocks coincided with the largest sea urchin grazing event observed in the NE Atlantic
2020
AbstractIn this contribution, we propose fishery driven predator release as the cause for the largest grazing event ever observed in the NE Atlantic. Based on the evolving appreciation of limits to population connectivity, published and previously unpublished data, we discuss whether overfishing caused a grazer bloom of the sea urchin (Strongylocentrotus droebachiensis) resulting in overgrazing of more than 2000 km2 kelp (Laminaria hyperborea) forest along Norwegian and Russian coasts during the 1970 s. We show that coastal fisheries likely depleted predatory coastal fish stocks through modernization of fishing methods and fleet. These fish were important predators on urchins and the reduct…
Diritti, sicurezza, solidarietà e responsabilità nella protezione della persona migrante
2018
1. Uno sguardo d’insieme. 2. Dopo Lisbona: le competenze dell’UE e la Carta dei diritti dinanzi alle crisi migratorie e all’onda lunga del populismo. 3. Protezione della persona migrante, Costituzione e decretazione di urgenza. 4. Solidarietà e diritti nella prospettiva costituzionale: uguaglianza, bisogni primari e contenuto essenziale
HUMAN RESOURCES MANAGEMENT IN MARITIME CONTAINER TERMINALS: OPTIMISATION METHODS AND POLICY IMPLICATIONS
2014
In the competitive environment of container transport, Container Terminals (CT) have to plan carefully the management of their resources and services in order to satisfy shipping companies’ requirements. Failure to do so may lead vessel operators to re-schedule their routes calling at new promising terminals. In particular, the optimal management of human resources is a major issue in port systems having low automation and high labour costs. This thesis aims at providing a large overview of current practices and issues concerning the management of dockworkers in the CT area, in order to suggest the analytical methods and policies for its improvement. The focus is on the operational plan (24…