Search results for "regime"

Interim 18f-PDGPET for Aggressive Non-Hodgking's Lymphoma: A Systematic Review and Meta-Analysis

2011

Abstract Abstract 5183 Background: The advantage of using interim 18F-fluorodeoxyglucose (FDG) positron-emission tomography (PET) scan in the clinical work-up of patients with non-Hodgkin's lymphoma (NLH) is unclear. Data from meta-analyses are inconclusive, mainly because of the low number of patients evaluated and heterogeneity among studies. New clinical investigations, focused on this topic, have been recently published. We conducted an updated systematic review on the role of 18PDG-PET for the interim evaluation in patients with aggressive lymphomas. Materials and Methods: Medline, Embase, Scopus and Databases were searched for relevant studies through March 2011. We included studies t…

Heart rate control with oral ivabradine in computed tomography coronary angiography: a randomized comparison of 7.5 mg vs 5 mg regimen.

2013

Background: Heart rate (HR) reduction is essential to achieve optimal image quality and diagnostic accuracy with computed tomography coronary angiography (CTCA). Administration of oral ivabradine seems to be more effective than beta-blockade in reducing HR in patients referred for CTCA. Methods: Two-hundred-fifty-nine consecutive patients referred for CTCA were prospectively enrolled. Patients not receiving beta-blocker at baseline (group 1) and those with beta-blocker therapy (group 2) were enrolled in the study. Each group was randomized into 3 parallel arms with 1:1:1 allocation. Patients who did not receive beta-blocker at baseline: underwent CTCA without beta blocker (n=49), and receiv…

Contributi firmati al volume "Alla ricerca di un ordine nuovo: Napoli e Palermo fra antico regime, rivoluzione e restaturazione (1759-1821)" tomo II,

2011

Portfolio diversification in the sovereign credit swap markets

2018

We develop models for portfolio diversification in the sovereign credit default swaps (CDS) markets and show that, despite literature findings that sovereign CDS spreads are affected by global factors, there is sufficient idiosyncratic risk to be diversified. However, we identify regime switching in the times series of CDS spreads and spread returns, and the optimal diversified strategies can be regime dependent. The developed models trade off the CVaR risk measure against expected return, consistently with the statistical properties of spreads. We consider three investment strategies suited for different CDS market participants: for investors with long positions, speculators that hold unco…

Pricing sovereign contingent convertible debt

2018

We develop a pricing model for Sovereign Contingent Convertible bonds (S-CoCo) with payment standstills triggered by a sovereign's Credit Default Swap (CDS) spread. We model CDS spread regime switching, which is prevalent during crises, as a hidden Markov process, coupled with a mean-reverting stochastic process of spread levels under fixed regimes, in order to obtain S-CoCo prices through simulation. The paper uses the pricing model in a Longstaff-Schwartz American option pricing framework to compute future state contingent S-CoCo prices for risk management. Dual trigger pricing is also discussed using the idiosyncratic CDS spread for the sovereign debt together with a broad market index. …

Mutamento del collegio nei processi per reati di criminalità organizzata

2007

I profili della rinnovazione della istruttoria dibattimentale per il caso di mutamento dei componenti il collegio (unitamente al correlativo giudizio di utilizzabilità degli atti assunti dal primo giudice ex artt. 525 e 526 c.p.p.) e i problemi legati ai parametri di ammissione della prova contenuti negli artt. 190-bis, 495 e 507 c.p.p. vengono affrontati in chiave critica. Le soluzioni proposte sono improntate ai canoni del ''giusto processo''. Lo sfondo processuale è relativo ad uno dei reati di cui all''art. 51, comma 3-bis, c.p.p., nel quale, una volta riaperto il dibattimento e data lettura, con assoluta priorità ai sensi dell''art. 190-bis c.p.p.

1914-1918. L'Album della Guerra: regime telescopico e montaggio fotografico della Storia

2014

Negli archivi europei un cercatore di immagini può davvero diventare il pescatore del mare di cui Hannah Arendt parla a proposito di Walter Benjamin collezionista, cioè di Benjamin storico. In breve, di Benjamin filosofo della storia. In particolare, si tratta di sapersi immergere, saper andare al fondo di un patrimonio fotografico enorme che mostra fin dal primo sguardo – e di sguardo si tratterà in modo esteso – una straordinaria accumulazione di immagini di guerra. La relazione tra fotografia e guerra, infatti, è stata sottolineata da molti pensatori e filosofi – e dallo stesso Benjamin –, ma anche da artisti e sperimentatori di tecniche fotografiche del XX secolo, e in particolare, da u…

La memoria de los verdugos de 1936 y la cultura de la impuni(bili)dad en la democracia posfranquista

2020

UIDB/04666/2020 UIDP/04666/2020 Este texto se interesa por los efectos de la producción académica sobre la construcción social del victimario, y se centra en el caso de los victimarios de la guerra española de 1936 y su estatus en la cultura de la democracia posfranquista. Escoge dos obras de especialistas dirigidas al público amplio y rastrea a partir de ellas cómo el tratamiento de los victimarios se encuentra predefinido por un marco que exonera de partida a determinados posibles perpetradores al figurar en la nómina de intelectuales y artistas que conforman el canon cultural del siglo XX. El enfoque alternativo que propone consiste en combinar una hermenéutica de los testimonios de posi…

Música, democratización y omnivoridad

2008

En el campo del análisis cultural, la teoría de la omnivoridad sostiene que los gustos estéticos han superado el esquema monolegitimista basado en la distinción jerárquica entre alta cultura y cultura popular y se han vuelto cada vez más variados y tolerantes. En este artículo, a partir del análisis de las prácticas musicales en España, en el contexto de la creciente difusión de la audición mediada, se estudia la evolución de las preferencias musicales; y se esboza el concepto de régimen de consumo cultural (en este caso, musical) como una herramienta analítica más compleja y adecuada que la omnivoridad. In the field of the analysis of culture, the theory of omnivorousness holds that aesthe…

Real-world experience with the all-oral, interferon-free regimen of ombitasvir/paritaprevir/ritonavir and dasabuvir for the treatment of chronic hepa…

2017

Summary Real-world studies are relevant to complement clinical trials on novel antiviral therapies against chronic hepatitis C; however, clinical practice data are currently limited. This study investigated effectiveness and safety of ombitasvir/paritaprevir/ritonavir (OBV/PTV/r)±dasabuvir (DSV)±ribavirin (RBV) for treatment of HCV genotype (GT) 1 and GT4 infection in a large real-world cohort. The German Hepatitis C Registry is an observational cohort study prospectively collecting clinical practice data on direct-acting antiviral therapies. Patients with GT1/4 infection treated with OBV/PTV/r±DSV±RBV were analysed. Effectiveness was assessed by sustained virologic response in 558 patients…