Search results for "relation"

Concensus Rorschach interaction patterns of families with an asthmatic child

1987

This paper reports a study of interaction in families with a child suffering from bronchial asthma. Eighteen families, subdivided into two groups according to the severity of the child's illness, were given the Consensus Rorschach following Willi's procedure. Quantitative assessments of family members on cognitive-affective functioning and social interaction were obtained. Factor analysis of quantitative scores revealed diversified interactional strategies among family member groups. Families as wholes varied as to patterns of cross-generational alliances and/or domination of different family members and could be clustered into four interactional pattern groups. There was no correlation bet…

Self‐esteem mediates the associations among negative affect, body disturbances, and interpersonal problems in treatment‐seeking obese individuals

2015

Background: This study investigated the relationship among negative affect, body image disturbances (BID), and interpersonal problems, and the mediat- ing effect of self-esteem in a group of treatment-seeking obese individuals. Methods: Four hundred twenty-two obese patients (85 males and 337 females) completed standardised measures that assessed negative affect, BID, self-esteem, and interpersonal problems. Results: Structural equation modelling showed that obese individuals with greater negative affect and BID reported higher interpersonal problems and that self-esteem mediated the relationships among negative affect, BID, and interpersonal problems. Conclusions: The mediating role of sel…

Finding the right dose of fulvestrant in breast cancer

2012

Fulvestrant is a selective estrogen receptor downregulator, behaving as a complete antagonist. It was initially approved, at a dose of 250 mg, to treat hormone dependant breast cancer in second line setting. However, a series of pharmacological and pre-clinical studies have suggested that a higher dose of 500 mg may be more effective. The present work summarizes and discusses clinical trials that have aimed to test the benefits of administering fulvestrant at a higher dose. The data support the use of a higher, and more possibly, effective dose of the agent.

Improving transparency of scientific reporting to increase value and reduce waste in mental health research.

2015

Mitochondrial compartment: a possible target of cadmium effects on breast epithelial cells.

2009

Cadmium–breast epithelial cell interactions were studied by analyzing some mitochondria-related aspects of stress response. We treated immortalized non-tumor breast cells with 5 or 50 μM CdCl2 for 24 or 96 h demonstrating that the exposure did not cause a significant mitochondrial proliferation, while it induced a significant increase in the respiratory activity and mitochondrial polarization. In addition, we found that hsp60 was up-regulated while hsp70 and COXII and COXIV were down-regulated. The mRNA for hsp70 remained constant and only the inducible form of the 70-kDa heat shock protein was over expressed. The mRNAs for COXII and COXIV remained constant after 24 h and increased after lo…

Micronucleus frequencies and clonogenic cell survival in TK6 cells exposed to changing dose rates under controlled temperature conditions.

2014

In most exposure scenarios the dose rate of exposure is not constant. Despite this, very little information exists on the possible biological effects of exposing cells to radiation under the conditions of a changing dose rate. The current study highlights interesting effects following exposure under these conditions.We constructed a new exposure facility that allows exposing cells inside an incubator and used it to irradiate human lymphoblastoid TK6 cells both after a moderate (0.48 Gy) and a high (1.1 Gy) dose, where the change in dose rate was, respectively, ≈ 17-fold (2.2-37 mGy/min) and ≈ 39-fold (2.7-106 mGy/min). Clonogenic survival and micronuclei (MN) induction were the chosen endpo…

Temperamento y crianza en la construcción de la personalidad. conducta agresiva, inestabilidad y prosociabilidad [Effect of temperament and upbringin…

2004

Resumen La investigacion realizada persigue un doble objetivo. El primero se dirige a estudiar la relacion que se establece entre la estructura de la personalidad del adolescente y la manifestacion de la agresion, de la inestabilidad emocional y de la conducta prosocial. El segundo objetivo pretende analizar del peso que muestran los habitos de crianza en la emision de las conductas agresivas, inestables y prosociales. La muestra esta constituida por 531 adolescentes, chicos y chicas de edades comprendidas entre los 12 y los 16 anos, escolarizados en Centros Publicos y Concertados, que cursan la Etapa Educativa de la Educacion Secundaria Obligatoria. En atencion al procedimiento aleatorio, …

An Overview of Cloud Computing Adoption Challenges in the Norwegian Context

2014

Cloud computing is dominating European countries' Information and Communication Technology (ICT) agenda. Although the European cloud market is mostly mature, there are still challenges to overcome. Norway is one of the European countries facing such challenges, despite it is a developed country in terms of quality of life and ICT development. This paper identifies the current state of cloud computing adoption challenges in Europe in general and Norway in specific, and the way they are addressed. This is achieved through analyzing research articles, reports published by consulting companies and official bodies, official online news articles, and documents published by official authorities. T…

N-Isopropylacrylamide andN-Isopropylmethacryl-amide: Cloud Points of Mixtures and Copolymers

2001

The cloud point curve of aqueous solutions of poly(N-isopropylacrylamide), poly(N-isopropylmethacrylamide) and their statistical copolymers were determined turbidimetrically. All the Systems demix upon heating at the cloud point temperature and mix reversibly upon cooling. The cloud points are independent of the total concentration of the solutions (dilute range) and of the sample thickness. Mixtures of the homopolymers poly(N-isopropylacrylamide) and poly(N-isopropylmethacrylamide) in water (ternary systems) exhibit two cloud points, which are nearly the same as the cloud points of the two binary systems homopolymer/water. A quantitative correlation was found between the cloud point temper…

SMART: Unique splitting-while-merging framework for gene clustering

2014

© 2014 Fa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Successful clustering algorithms are highly dependent on parameter settings. The clustering performance degrades significantly unless parameters are properly set, and yet, it is difficult to set these parameters a priori. To address this issue, in this paper, we propose a unique splitting-while-merging clustering framework, named "splitting merging awareness tactics" (SMART), which does not require any a priori knowledge of either the number …