Search results for "relation"

showing 10 items of 10542 documents

Brain event-related potentials (ERPs) measured at birth predict later language development in children with and without familial risk for dyslexia.

2005

We report associations between brain event-related potentials (ERPs) measured from newborns with and without familial risk for dyslexia and these same children's later language and verbal memory skills at 2.5, 3.5, and 5 years of age. ERPs to synthetic consonant-vowel syllables (/ba/, /da/, /ga/; presented equiprobably with 3,910-7,285 msec interstimulus intervals) were recorded from 26 newborns at risk for familial dyslexia and 23 control infants participating in the Jyvaskyla Longitudinal Study of Dyslexia. The correlation and regression analyses showed that the at-risk type of response pattern at birth (a slower shift in polarity from positivity to negativity in responses to /ga/ at 540-…

medicine.medical_specialtyLongitudinal studygenetic structuresCognitive NeuroscienceExperimental and Cognitive PsychologyAudiologybehavioral disciplines and activitiesLateralization of brain functionFunctional LateralityDevelopmental psychologyCorrelationDyslexiaEvent-related potentialMemoryPhoneticsRisk FactorsmedicineHumansChildEvoked Potentialsmusculoskeletal neural and ocular physiologyDyslexiaInfant NewbornBrainElectroencephalographymedicine.diseaseLanguage developmentElectrooculographyNeuropsychology and Physiological PsychologyCerebrovascular CirculationPositron-Emission TomographySpeech PerceptionVerbal memoryPsychologyNeurocognitivepsychological phenomena and processesChild LanguageCortex; a journal devoted to the study of the nervous system and behavior
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Correlation between fecal incontinence and quality of life after low anterior resection for rectal cancer

2014

SUMMARY Aim: The purpose of this study was to investigate the correlation between fecal incontinence and quality of life after low anterior resection and long-term follow-up. Methods: For 72 patients with coloanal or low colorectal anastomosis, the quality of life was determined by the European Organisation for Research and Treatment of Cancer (EORTC) questionnaires C-30 and CR-38. The Vaizey score was used for assessment of fecal incontinence. Results: The risk of fecal incontinence significantly increased with a lower level of anastomosis (p < 0.001). The QLQ CR-38 did not discern differences between patients. The OLQ C-30 only found significantly worse social and role function in pat…

medicine.medical_specialtyLow Anterior Resectionbusiness.industryColorectal cancerGastroenterologyUrologyCancerAnastomosismedicine.diseaseCorrelationOncologyQuality of lifemedicineFecal incontinencemedicine.symptomColoanal anastomosisbusinessColorectal Cancer
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Correlation between short-term air pollution exposure and unprovoked lung embolism. Prospective observational (Contamina-TEP Group)

2020

Background The aim was to analyze the temporal relationship between short-term air pollution exposure and acute symptomatic unprovoked pulmonary embolism (PE). Patients/methods We performed a prospective, multicenter study in consecutive patients diagnosed with acute symptomatic unprovoked PE from February 2012 to January 2013. We analyzed demographic and clinical data, patients' addresses, meteorological and air pollutants data (PM10, SO2, CO, NO2, ozone emission data). We considered the number of days the patient had symptoms, and the study period constituted the previous 30 days. Likewise, the mean annual data of the reference season were calculated as well as the data of the 30-day stud…

medicine.medical_specialtyLung embolismAir pollution exposureAir pollution030204 cardiovascular system & hematologyCorrelation03 medical and health sciences0302 clinical medicineAir pollutantsInternal medicineAir PollutionmedicineHumansProspective StudiesLungNitrogen dioxideAir Pollutantsbusiness.industryPulmonary embolismHematologyEnvironmental Exposuremedicine.diseasePulmonary embolismMulticenter study030220 oncology & carcinogenesisPyrazinesObservational studyParticulate MatterbusinessPulmonary EmbolismParticulate matterAir pollutants
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Induction of c-fos gene expression by the selective sigma receptor ligand EMD 57445 in rat brain.

1996

Based on animal studies it has been reasoned that ligands to sigma binding sites might be effective in the treatment of schizophrenic disorders and may also be used to investigate this largely elusive disorder on a molecular level. Expression patterns of c-fos in rat brain were studied following treatment with single doses of the sigma ligand EMD 57445 (0.3, 1, 3, 30 mg/kg s.c.). Specific c-fos gene expression was detected at all concentrations tested in various cortical areas. The signals observed were dose-dependent with the highest intensities in the piriform cortex. Strong signals were also detected in hippocampal areas CA 1,2,3 and the gyrus dentatus, as well as in the medial habenula …

medicine.medical_specialtyMammillary bodyNucleus accumbensHippocampal formationc-FosHippocampusRats Sprague-DawleyPiperidinesPiriform cortexInternal medicinemedicineAnimalsReceptors sigmaPharmacology (medical)OxazolesBiological PsychiatryIn Situ HybridizationPharmacologybiologyDose-Response Relationship DrugChemistryOlfactory tubercleBrainRatsPsychiatry and Mental healthEndocrinologyNeurologyHypothalamusIslands of Callejabiology.proteinFemaleNeurology (clinical)Proto-Oncogene Proteins c-fosAntipsychotic AgentsEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
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Academic competence, teacher–student relationship, and violence and victimisation in adolescents: The classroom climate as a mediator

2021

School violence is a serious social and public health problem prevalent worldwide. Although the relevance of teacher and classroom factors is well established in the literature, few studies have focused on the role of teacher perceptions in school violence and victimisation and the potential mediational role of classroom climate in this relationship. A total of 2399 adolescents (50% girls), aged between 11 and 18 years (M = 14.65, SD = 1.78) and enrolled in five Spanish Secondary Compulsory Education schools completed measures of classroom climate, school violence towards peers and perception of peer victimisation, and their teachers informed about their academic competence and the teacher&…

medicine.medical_specialtyMediation (statistics)AdolescentHealth Toxicology and Mutagenesismedia_common.quotation_subjectViolència escolarProtective factorlcsh:Medicineacademic competence050109 social psychologyViolenceCompulsory educationVictimisationteacher–student relationshipArticleStructural equation modelingDevelopmental psychologyclassroom climatePerceptionmedicineHumansmediation0501 psychology and cognitive sciencesadolescentsChildStudentsCrime Victimsmedia_commonClassroom climateschool violenceSchoolsPublic healthlcsh:R05 social sciencesPublic Health Environmental and Occupational HealthBullyingschool victimisationFemaleViolència juvenilPsychology050104 developmental & child psychology
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Multidisciplinary system for detecting medication errors in antineoplastic chemotherapy.

2009

Objective. To analyze medication errors (MEs) in a multidisciplinary system with a Computerized Pharmacotherapy Process (CPP) in cancer patients. Design. A longitudinal, prospective 2-year (January 2003 —to December 2004) cohort study was made in adult patients administered antineoplastic treatment in Services of Oncology and Haematology. MEs were identified by double cross-validation of each stage of the pharmacotherapeutic process (prescription, preparation, dispensing, administration, and follow-up) carried out by the multidisciplinary team (physician, pharmacist, nurse) with CPP assistance. Variables. Number of MEs per 1000 patient-days, percentage according to the stage of the pharmac…

medicine.medical_specialtyMedication Systems Hospitalanimal structuresInterprofessional RelationsPharmacistNursesAntineoplastic AgentsPharmacistsCohort StudiesHospitals UniversityPharmacotherapyMultidisciplinary approachAntineoplastic chemotherapyPhysiciansmedicineHumansMedication ErrorsPharmacology (medical)Longitudinal StudiesProspective StudiesMedical prescriptionStage (cooking)Adult patientsbusiness.industrySurgeryOncologyEmergency medicinebusinessCohort studyFollow-Up StudiesJournal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
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Pharmacological Characterization of Loss of Function Mutations of the Human Melanocortin 1 Receptor That Are Associated with Red Hair

2004

Variation in skin color is the major host risk factor for melanoma and other forms of skin cancer. Individuals with red hair show an increased ratio of phaeomelanin to eumelanin in both hair and skin. This ratio is regulated by the melanocortin (MC) 1 receptor. There are several common point mutations in the human MC1 receptor that are overrepresented in North European red-heads, and in individuals with pale skin. In order to determine the functional significance of these mutations, we expressed the Asp84Glu, Val92Met, Arg163Gln, and Asp294His variants of the human MC1 receptors in eukaryotic cells and determined their ability to bind alpha-melanocyte stimulating hormone (MSH) peptides and …

medicine.medical_specialtyMelanocyte-stimulating hormoneMolecular Sequence DataDermatologyBiologyKidneymedicine.disease_causeBiochemistrypolymorphismStructure-Activity RelationshipGPCRInternal medicineCyclic AMPmedicineHumansPoint MutationpigmentationAmino Acid SequencemelanocortinHair ColorReceptorMSHMolecular BiologyCells CulturedG protein-coupled receptorMutationintegumentary systemMelanomaPoint mutationCell Biologymedicine.diseaseProtein Structure TertiaryEndocrinologyalpha-MSHMelanocortinReceptor Melanocortin Type 1Melanocortin 1 receptorJournal of Investigative Dermatology
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Intervention of two voltage-dependent calcium-entry pathways in the contractile response to acetylcholine and KCl in rat uterus.

1994

The contractile response of rat uterine smooth muscle was investigated. Verapamil and diltiazem concentration-dependently relax the sustained contractions induced by KCl (56 mmol/l) or acetylcholine (10(-4) mol/l). This inhibitory effect was not not freely reversed by washing the tissue and subsequently no contractile response was obtained in depolarized tissue, but a lower biphasic response (phasic and tonic) to acetylcholine was observed. Addition of cumulative concentrations of CaCl2 (1.2-19.2 mmol/l) induced a partial recovery of the contractile response to acetylcholine or KCl, but addition of MgCl2 (1.2-19.2 mmol/l did not. When the channel was reactivated by a third addition of KCl o…

medicine.medical_specialtyMuscle RelaxationTonic (physiology)Membrane PotentialsPotassium ChlorideDiltiazemUterine ContractionInternal medicinemedicineAnimalsDiltiazemRats WistarPharmacologyMembrane potentialDose-Response Relationship DrugChemistryUterusMuscle SmoothGeneral MedicineAcetylcholineRatsElectrophysiologyDose–response relationshipEndocrinologyVerapamilVerapamilCalciumFemaleCalcium Channelsmedicine.symptomAcetylcholinemedicine.drugMuscle contractionPharmacology
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Comparative study of the rat uterine smooth muscle relaxant activity of three bisbenzyltetrahydroisoquinolines with tetrandrine

1993

Abstract The relaxant activity of three bisbenzyltetrahydroisoquinolines—obaberine, popisonine and lindoldhamine—was examined in rat isolated uterus and their inhibitory potencies were compared with that of tetrandrine. All alkaloids tested relaxed KCl-depolarized rat uterus and totally or partially inhibited oxytocin-induced rhythmic contractions. The degree of methylation of the free phenolic hydroxy groups and the loss of one diarylether bridge influence the potency of relaxant action of these alkaloids. Only alkaloids with absolute configuration 1R,1′S or 1R1′R acted intracellularly, promoting relaxation of contractile responses induced by oxytocin or vanadate in a Ca2+-free medium.

medicine.medical_specialtyMuscle RelaxationUterusPharmaceutical Sciencechemistry.chemical_elementIn Vitro TechniquesBiologyCalciumOxytocinBenzylisoquinolinesUterine contractionStructure-Activity RelationshipUterine Contractionchemistry.chemical_compoundAlkaloidsInternal medicinemedicineAnimalsVanadateRats WistarPharmacologyAlkaloidUterusMuscle SmoothCalcium Channel BlockersIsoquinolinesRatsTetrandrinemedicine.anatomical_structureMuscle relaxationEndocrinologyOxytocinchemistryPotassiumCalciumFemaleVanadatesmedicine.symptommedicine.drugJournal of Pharmacy and Pharmacology
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Attachment styles in children affected by migraine without aura

2013

Maria Esposito,1 Lucia Parisi,2 Beatrice Gallai,3 Rosa Marotta,4 Anna Di Dona,1 Serena Marianna Lavano,2 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Department of Psychiatry, The Magna Graecia University of Catanzaro, Catanzaro, ItalyBackground: In recent years, great attention has been given to the presence of psychological problems and psyc…

medicine.medical_specialtyNeuropsychiatric Disease and TreatmentAuraVisual analogue scaleNeurosciences. Biological psychiatry. NeuropsychiatrySpearman's rank correlation coefficientCorrelationchildrenmedicineAttachment theoryPain perceptionPsychiatryRC346-429Separation Anxiety TestBiological PsychiatryOriginal Researchbusiness.industrymigraine without aura; children; attachment stylemedicine.diseaseSettore MED/39 - Neuropsichiatria InfantilePsychiatry and Mental healthMigrainemigraine without auraPopulation studyNeurology. Diseases of the nervous systemattachment stylebusinessClinical psychologyRC321-571
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