Search results for "relative"

showing 10 items of 1094 documents

Survival of Myeloid Malignancies in EUROPE: Results of the HAEMACARE Project.

2009

Abstract Abstract 3911 Poster Board III-847 Background Updated ICD-O and WHO classifications of Haematological Malignancies (HMs) take into account cell lineage, genotype, morphological aspects, immuno-histochemical and genetic characteristics, and clinical behaviour of the disease, dividing Lymphoid and Myeloid neoplasms in subcategories with possible similar aetiology or prognosis. Thus, good quality of morphological data on HMs is capital. The HAEMACARE project aimed to increase standardization and the availability of Cancer Registries (CRs) morphological data on HMs, in order to improve comparability of incidence, survival and prevalence across Europe. This study aims to present the HAE…

Acute leukemiaPediatricsmedicine.medical_specialtyMyeloidRelative survivalbusiness.industryIncidence (epidemiology)ImmunologyMyeloid leukemiaCell BiologyHematologyDiseasemedicine.diseaseBiochemistryLeukemiamedicine.anatomical_structureEtiologymedicinebusinessDemographyBlood
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Influence of training and a maximal exercise test in analytical variability of muscular, hepatic, and cardiovascular biochemical variables.

2014

Short, middle, and long-term exercise, as well as the relative intensity of the physical effort, may influence a broad array of laboratory results, and it is thereby of pivotal importance to appropriately differentiate the 'physiologic' from the 'pathological' effects of exercise. Therefore, the values of some biomarkers in physically active subjects may be cautiously interpreted since the results may fall outside the conventional reference ranges. It has been demonstrated that middle and long-term endurance and/or strenuous exercise triggers transient elevations of muscular and cardiac biomarkers. However, no data have been published about the effect of short-term maximal exercise test on …

AdultCalcitoninMalemedicine.medical_specialtyCardiac biomarkersCardiovascular biomarkersCalcitonin Gene-Related PeptideClinical BiochemistryPhysical ExertionPhysical medicine and rehabilitationReference ValuesInternal medicineNatriuretic Peptide BrainmedicineCreatine Kinase MB FormHumansAspartate AminotransferasesProtein PrecursorsMuscle SkeletalPathologicalExerciseRelative intensitybiologyL-Lactate Dehydrogenasebusiness.industryC-reactive proteinSkeletal muscleHeartGeneral Medicinegamma-GlutamyltransferaseLaboratory resultsPeptide FragmentsTroponinmedicine.anatomical_structureexercise; laboratory; biomarkersC-Reactive ProteinLiverCardiologybiology.proteinExercise TestPhysical EnduranceMaximal exerciseSedentary BehaviorbusinesslaboratoryBiomarkersScandinavian journal of clinical and laboratory investigation
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Survival of ovarian cancer patients in Germany in the early 21st century: a period analysis by age, histology, laterality, and stage.

2012

Population-based studies on ovarian cancer providing survival estimates by age, histology, laterality, and stage have been sparse. We aimed to derive the most up-to-date and detailed survival estimates for ovarian cancer patients in Germany. We used a pooled German national dataset including data from 11 cancer registries covering 33 million populations. A total of 21 651 patients diagnosed with ovarian cancer in 1997-2006 were included. Period analysis was carried out to calculate the 5-year relative survival (RS) for the years 2002-2006. Trends in survival between 2002 and 2006 were examined using model-based period analysis. Age adjustment was performed using five age groups (15-44, 45-5…

AdultCancer Researchmedicine.medical_specialtyAdolescentDatabases FactualEpidemiologyPopulationAge adjustmentYoung AdultGermanymedicineCarcinomaHumansYoung adulteducationAgedDemographyNeoplasm StagingGynecologyOvarian Neoplasmseducation.field_of_studyRelative survivalbusiness.industryNot Otherwise SpecifiedPublic Health Environmental and Occupational HealthAge FactorsCancerMiddle Agedmedicine.diseaseSurvival RateOncologyFemaleOvarian cancerbusinessEuropean journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)
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Population attributable risk for ovarian cancer

2000

Parity, oral contraceptive (OC) use, age at menopause, a family history of the disease and selected aspects of diet have been related to the risk of ovarian cancer. The quantification of their impact on a population level may help focus and rank the importance of potential prevention strategies. Using data from a case-control study conducted in Italy between 1983 and 1991 on 971 ovarian cancer cases and 2758 control women we computed the multivariate relative risk estimates, and population attributable risks (PARs), i.e. the proportion of ovarian cancers that would have been avoided if a given exposure had not been present in the population. Overall, the PARs were 5% for nulliparity, 12% fo…

AdultCancer Researchmedicine.medical_specialtyEpidemiologyPopulationEpidemiology; Risk factors; WomenAge DistributionmedicineHumansWomenRisk factorFamily historyAge of OnseteducationMultivariate AnalysiAgedGynecologyOvarian Neoplasmseducation.field_of_studybusiness.industryObstetricsOvarian NeoplasmCase-control studyMiddle Agedmedicine.diseaseDietMenopauseParityOncologyItalyRisk factorsRelative riskCase-Control StudiesAttributable riskMultivariate AnalysisFemaleMenopauseCase-Control StudieOvarian cancerbusinessHumanContraceptives Oral
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Impact of Low Maternal Education on Early Childhood Overweight and Obesity in Europe

2016

BackgroundComparable evidence on adiposity inequalities in early life is lacking across a range of European countries. This study investigates whether low maternal education is associated with overweight and obesity risk in children from distinct European settings during early childhood. MethodsProspective data of 45 413 children from 11 European cohorts were used. Children's height and weight obtained at ages 4-7 years were used to assess prevalent overweight and obesity according to the International Obesity Task Force definition. The Relative/Slope Indices of Inequality (RII/SII) were estimated within each cohort and by gender to investigate adiposity risk among children born to mothers …

AdultCross-Cultural ComparisonMalePediatric ObesityEpidemiologyMothers030209 endocrinology & metabolismMaternal educationOverweightObesity - ChildrenEducation03 medical and health sciences0302 clinical medicinePregnancyRisk FactorsPrevalencemedicineHumansProspective Studies030212 general & internal medicineEarly childhoodMaternal Behaviorbusiness.industryInfant NewbornAbsolute risk reductionInfantmedicine.diseaseObesityEuropeSocioeconomic FactorsChild PreschoolRelative riskPediatrics Perinatology and Child HealthCohortEducational StatusLife course approachFemalemedicine.symptombusinessDemographyCohort studyPaediatric and Perinatal Epidemiology
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Type of employment relationship and mortality: prospective study among Finnish employees in 1984-2000

2009

Background: The study investigated the relationship between the type of employment (permanent/temporary) contract and mortality. Factors through which temporary employment was expected to be associated with increased mortality were the degree of satisfaction with the uncertainty related to temporary work situation (Study 1) and the voluntary/involuntary basis for temporary work (Study 2). Methods: In Study 1 the data consisted of representative survey on Finnish employees in 1984 ( n = 4502), which was merged with register-based follow-up data in Statistics Finland covering years 1985–2000. In Study 2 the data consisted of representative survey on Finnish employees in 1990 ( n = 3502) with …

AdultEmploymentMalemedicine.medical_specialtymedia_common.quotation_subjectTemporary workCause of DeathRisk of mortalitymedicineHealth Status IndicatorsHumansProspective StudiesRegistriesMortalityProspective cohort studyFinlandProportional Hazards Modelsmedia_commonProportional hazards modelbusiness.industryData CollectionPublic healthPublic Health Environmental and Occupational HealthMiddle AgedFeelingTurnoverRelative riskFemalebusinessDemographyThe European Journal of Public Health
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C4BQ0: a genetic marker of familial HCV-related liver cirrhosis

2004

Source Department of Medicine and Pneumology, V Cervello Hospital, Via Trabucco 180, 90146 Palermo, Italy. lindpas@yahoo.it Abstract BACKGROUND AND METHODS: Host may have a role in the evolution of chronic HCV liver disease. We performed two cross-sectional prospective studies to evaluate the prevalence of cirrhosis in first degree relatives of patients with cirrhosis and the role of two major histocompatibility complex class III alleles BF and C4 versus HCV as risk factors for familial clustering. FINDINGS: Ninety-three (18.6%) of 500 patients with cirrhosis had at least one cirrhotic first degree relative as compared to 13 (2.6%) of 500 controls, (OR 7.38; CI 4.21-12.9). C4BQ0 was signifi…

AdultGenetic MarkersLiver Cirrhosismedicine.medical_specialtyCirrhosisAdolescentFamilial clusteringFamilial clusteringGastroenterologyLiver cirrhosiC4BQ0Liver diseaseInternal medicineHCV diffusionComplement C4bPrevalencemedicineHumansProspective StudiesAlleleFamily historyFirst-degree relativesMHC class III allelesChildProspective cohort studyAllelesAgedAged 80 and overHepatologybusiness.industryGastroenterologyHepatitis C ChronicMiddle Agedmedicine.diseaseCross-Sectional StudiesGenetic markerbusinessC4BQ0; Familial clustering; HCV diffusion; Liver cirrhosis; MHC class III allelesDigestive and Liver Disease
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Healthcare students’ flu vaccine uptake in the last 5 years and future vaccination acceptance: is there a possible association?

2020

Background:Despite the free-of-charge offer of influenza vaccines to at-risk subgroups, vaccine coverage remains low and far from the target, probably due to the false myths and misperceptions. We aimed to explore the healthcare students’ vaccination behavior and beliefs to find any association between vaccination uptake during the last 5 years and future vaccination acceptance.Study design:A multicentre cross-sectional study.Methods:From Oct 2017 to Nov 2018, the Italian healthcare students from 14 different universities in 2017/2018 were enrolled, through an online and anonymous questionnaire previously validated. Absolute and relative frequencies were calculated and Pearson's Chi-square …

AdultHealth Knowledge Attitudes PracticeStudents MedicalAdolescentUniversitiesEpidemiologySurvey and QuestionnairesIntention03 medical and health sciencesYoung Adult0302 clinical medicineMultinomial logistic regression modelStatistical significanceSurveys and QuestionnairesHealth careInfluenza HumanMedicineHumans030212 general & internal medicineAssociation (psychology)Students0303 health sciences030306 microbiologybusiness.industryHealth PolicyVaccinationPublic Health Environmental and Occupational HealthPatient Acceptance of Health CareConfidence intervalTest (assessment)VaccinationCross-Sectional StudiesHealth Occupations; Influenza Vaccines; Students; Survey and QuestionnairesHealth OccupationsInfluenza VaccinesRelative riskStudents NursingOriginal ArticlebusinessDemography
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Second study on the recurrence risk of isolated esophageal atresia with or without trachea-esophageal fistula among first-degree relatives: no eviden…

2013

BACKGROUND Esophageal atresia with/without trachea-esophageal fistula (EA/TEF) denotes a spectrum of severe congenital malformations. The aim of this systematic study was to determine both the recurrence risk for EA/TEF, and the risk for malformations of the VATER/VACTERL association spectrum, in first-degree relatives of patients with isolated EA/TEF. METHODS A total of 108 unrelated patients with isolated EA/TEF were included. These individuals had 410 first-degree relatives including 194 siblings. The presence of EA/TEF and malformations of the VATER/VACTERL association spectrum in relatives was systematically assessed. Data from the EUROCAT network were used for comparison. RESULTS None…

AdultHeart Defects CongenitalMaleRiskEmbryologymedicine.medical_specialtyAdolescentFistulaInheritance PatternsLimb Deformities CongenitalAnal CanalKidneyGastroenterologyRecurrence riskAnus ImperforateEsophagusInternal medicinemedicineHumansEsophageal FistulaFirst-degree relativesChildEsophageal Atresiabusiness.industrySiblingsVATER/VACTERL ASSOCIATIONGeneral Medicinemedicine.diseaseVACTERL associationSpinePedigreeTracheaRadiusAtresiaCase-Control Studiesembryonic structuresPediatrics Perinatology and Child HealthCohortFemalebusinessDevelopmental BiologyTracheoesophageal FistulaBirth defects research. Part A, Clinical and molecular teratology
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Psychiatric disorders in childhood cancer survivors in Denmark, Finland, and Sweden: a register-based cohort study from the SALiCCS research programm…

2022

BACKGROUND A childhood cancer diagnosis and treatment-induced somatic late effects can affect the long-term mental health of survivors. We aimed to explore whether childhood cancer survivors are at higher risk of psychiatric disorders later in life than their siblings and the general population. METHODS In this register-based cohort study (part of the Socioeconomic Consequences in Adult Life after Childhood Cancer [SALiCCS] research programme), we included 5-year survivors of childhood cancer diagnosed before 20 years of age between Jan 1, 1974 and Dec 31, 2011, in Denmark, Finland, and Sweden. In Denmark and Sweden, 94��7% of individuals were born in a Nordic country (ie, Denmark, Finland,…

AdultHospitals PsychiatricMalemedicine.medical_specialtyAdolescentFinland/epidemiologyDenmarkPopulationPsychiatric Department HospitalCohort StudiesYoung AdultQuality of lifeCancer SurvivorsSurvivorship curveMedicinePsychiatric hospitalHumansRegistriesSiblingeducationPsychiatry610 Medicine & healthChildBiological PsychiatryFinlandSwedeneducation.field_of_studybusiness.industryMental DisordersSiblingsRegistries/statistics & numerical dataInfantMiddle AgedDenmark/epidemiologyPsychiatric Department Hospital/statistics & numerical dataPsychiatry and Mental healthSweden/epidemiologyHospitals Psychiatric/statistics & numerical dataRelative riskChild PreschoolPopulation studyFemalebusinessMental Disorders/epidemiology360 Social problems & social servicesCancer Survivors/statistics & numerical dataCohort studyThe lancet. Psychiatry
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