Search results for "release"
showing 10 items of 602 documents
The upgraded ISOLDE yield database – A new tool to predict beam intensities
2020
At the CERN-ISOLDE facility a variety of radioactive ion beams are available to users of the facility. The number of extractable isotopes estimated from yield database data exceeds 1000 and is still increasing. Due to high demand and scarcity of available beam time, precise experiment planning is required. The yield database stores information about radioactive beam yields and the combination of target material and ion source needed to extract a certain beam along with their respective operating conditions. It allows to investigate the feasibility of an experiment and the estimation of required beamtime. With the increasing demand for ever more exotic beams, needs arise to extend the functi…
Effects of radiation and hydrogen-loading on the performances of raman-distributed temperature fiber sensors
2015
International audience; The integration of Raman-distributed temperature fiber-based sensors (RDTS) into the envisioned French deep geological repository for nuclear wastes, called Cigéo requires evaluating how the performances of RDTS evolve in harsh environments, more precisely in presence of H2 or γ-rays. Both H2 and radiations are shown to affect the temperature measurements made with the single-ended RDTS technology. The amplitudes of the observed effects depend on the different classes of multimode fibers varying in terms of composition and coatings. By selecting the most tolerant fiber structure for the sensing, we could maintain the RDTS performances for such application. A hardeni…
Liposomes as nonspecific nanocarriers for 5-Fluorouracil in the presence of cyclodextrins
2021
Abstract 5-Fluorouracil (5-FU) is one of anticancer drugs with broad activity. Due to its severe side effects, recent studies concentrate on new ways of directed 5-FU delivery and its release in ill tissue. One of selective carriers could be cyclodextrins and liposomes. The combination of novel methods, leading to formation of inclusion complexes (IC) between host molecule of β-cyclodextrin (β-CD) or 2-hydroxypropyl-β-cyclodextrin (HP-β-CD) and 5-FU guest and its subsequent encapsulation in dipalmitoylphosphatidylcholine (DPPC) liposomes is studied experimentally in the present work. Several methods are applied to proof the encapsulation of the analysed drug and its release over time at 37 …
An information systems design product theory for the class of integrated requirements and release management systems
2010
High-tech companies conducting product development need to collect and analyze requirements effectively, plan and implement releases, and allocate requirements to appropriate releases. Requirements and release management are complicated because development activities typically are scattered across multiple sites, involve multiple partners in different countries, leverage various development methods and tools, and are realized through various organizational arrangements such as release projects in organizations structured around products and permanent release teams in organizations responsible for the long-term development and maintenance of strategic software and hardware assets. Flexible, …
Risk analysis using fuzzy set theory of accidental exposure of medical staff during brachytherapy procedures
2010
Using fuzzy set theory, this paper presents results from risk analyses that explore potential exposure of medical operators working in a high dose rate brachytherapy irradiation plant. In these analyses, the HEART methodology, a first generation method for human reliability analysis, has been employed to evaluate the probability of human error. This technique has been modified on the basis of fuzzy set concepts to take into account, more directly, the uncertainties of the so-called error-promoting factors on which the method is based. Moreover, with regard to some identified accident scenarios, fuzzy potential dose was also evaluated to estimate the relevant risk. The results also provide s…
Euclid preparation - XVII. Cosmic Dawn Survey: Spitzer Space Telescope observations of the Euclid deep fields and calibration fields
2022
Artículo escrito por un elevado núnmero de autores, sólo se referencian el qque aparece en primer lugar, los autores pertenecientes a la UAM y el nombre del grupo de colaboración, si lo hubiere
Assessment wine aroma persistence by using an in vivo PTR-ToF-MS approach and its relationship with salivary parameters
2019
To better understand wine aroma persistence, the nasal cavity of nine volunteers was monitored by Proton Transfer Reaction-Time of Flight-Mass Spectrometry (PTR-ToF-MS) after they rinsed their mouths with three rosé wines (one control and the same wine supplemented with two tannin extracts) during four minutes. Wines were aromatised with a mixture of five target aroma compounds. Results showed that wine aroma persistence was highly compound-dependent: while esters disappeared very fast, other compounds such as linalool remained in the oral cavity for longer times after wine expectoration. A low effect of tannins (at 50 mg/L) on nasal cavity parameters was observed, with the exception for th…
Relationships between oral characteristics, bolus formation and aroma compound releases during the consumption of fat spread in humans
2011
Source : 13th Weurman Flavour Research Symposium - Zaragoza, Spain - September 27th – 30th, 201; International audience; The release and perception of flavour compounds is an important factor for the acceptance of a food product. It is a complex echanism that depends not only on the food’s chemical composition and structure, but also on in-mouth mechanisms involved in its breakdown. To date, most of the studies have been focused on hard or semi-hard product such as cheese for instance (1, 2). Among the works published on dairy product, fat spreads were not considered while they represent an important market. However these products are particularly interesting by their structure and composit…
Inter-individual variability in aroma release during sweet mint consumption
2011
Inter-individual variations of in vivo aroma release kinetics have been observed widely in the literature. However, the corresponding causes are yet to be clearly identified. For this purpose, 68 subjects in whom salivary flow rates (at rest and Parafilm™-stimulated) had been determined were recruited for the study. The release of menthone was measured using atmospheric pressure ionisation–mass spectrometry during the consumption of a sweet mint tablet. The subjects complied with an imposed protocol of oral movements. Inter-individual variability was investigated through a qualitative analysis of the oral movements inducing menthone release, and through quantitative analysis. Swallowing eve…
In-mouth mechanisms leading to flavor release and perception.
2011
Review; International audience; During eating, foods are submitted to two main oral processeschewing, including biting and crushing with teeth, and progressive impregnation by saliva resulting in the formation of a cohesive bolus and swallowing of the bolus. Texture influences the chewing behavior, including mastication and salivation, and in turn, these parameters influence texture perception and bolus formation. During this complex mouth process, flavor compounds are progressively released from the food matrix. This phenomenon is mainly dependent on the food texture, the composition and in-mouth breakdown, and on saliva impregnation and activity, but an individual's anatomical and physiol…