Search results for "reo"

showing 10 items of 7464 documents

"Ronja rider och Steffan skejtar" : jämställdhet och framställningar av könen i Klick 7 och i Hallonbåt 1-2

2017

Tämän kandidaatintutkielman tarkoituksena on selvittää, miten sukupuolet ovat edustettuina kahdessa ruotsin kielen oppikirjassa, Klick 7:ssä ja Hallonbåt 1–2:ssa. Tietoisuus sukupuolten välisestä tasa-arvosta on lisääntynyt yhteiskunnassa ja tässä tutkimuksessa pyritään selvittämään, onko se yhdessä opetussuunnitelmien muutosten kanssa vaikuttanut oppikirjojen sisältöön sukupuolten välisen tasa-arvon ja sukupuoliin liittetävien stereotypioiden osalta. Tutkielma on toteutettu sekä laadullisena että määrällisenä sisällönanalyysina. Tutkimusmateriaalina ovat oppikirjat Klick 7 ja Hallonbåt 1–2. Tutkielmassani selvitän, miten sukupuolten välinen tasa-arvo ilmenee oppikirjoissa tarkastelemalla s…

tasa-arvosukupuoliroolikvalitatiivinen sisällönanalyysioppikirjastereotypiakvantitatiivinen sisäl-lönanalyysisukupuolistereotypiasukupuoli
researchProduct

Tautību stereotipu saistība ar uztverto ģeogrāfisko attālumu

2015

Šī pētījuma mērķis ir noskaidrot vai pastāv saistība starp tautības stereotipiem un ģeogrāfisko attālumu. Šī darba izvirzītās hipotēzes pieņem, ka stereotipu piedēvējums par tuvāk dzīvojošajām tautām ir homogēnāks nekā par tālāk dzīvojošām tautām, un otrā hipotēze pieņem, ka par ģeogrāfiski tuvākām tautām pārliecība par sniegtajām stereotipiskajām īpašībām un tautu raksturojošajām pazīmēm ir augstāka. Šajā pētījumā piedalījās 100 Latvijā dzīvojoši cilvēki no kuriem 58 bija sievietes un 42 vīrieši. Vidējais vecums respondentiem bija 34 gadi (15 – 66 gadi). Pētījumā tika izmantota oriģināla aptauja pēc kuras ir iespējams noteikt tautību stereotipu – stereotipisko īpašību un stereotipisko pazī…

tautapārliecībaetniskie stereotipistereotipiPsiholoģija
researchProduct

TECNICHE COSTRUTTIVE NEL MEDITERRANEO DALLA STEREOTOMIA AI CRITERI ANTISISMICI

2016

Il volume raccoglie una serie di saggi relativi alle architetture del bacino mediterraneo, rientranti in quattro aree tematiche tra loro strettamente interconnesse relative alla stereotomia, agli scambi e trasferimenti tecnologici, alle tecniche antisismiche e, infine, alla storiografia. Lo studio della tradizione costruttiva in pietra, della quale sono esaminati esempi significativi e indagate le connessioni, le influenze, le modalità di circolazione di idee è volta anche alla ricerca delle modalità di trasmissione di saperi costruttivi e di innovazioni tecnologiche nell’ambito dei cantieri. I temi legati all'utilizzo di tecniche specificamente antisismiche sono approfonditi in relazione a…

tecniche antisismichestoriografiastoriografia trasferimenti tecnologicistereotomia; tecniche antisismiche; storiografia trasferimenti tecnologicitrasferimenti tecnologicistereotomia; tecniche antisismiche; storiografia; trasferimenti tecnologicistereotomiaSettore ICAR/18 - Storia Dell'Architettura
researchProduct

Perceived threat and prejudice towards immigrants and Russian minorities living in Finland

2017

This study is an attempt to better understand the relationship between Finns and Russian minorities living in Finland. This study considers the role of perceived threats to the attitudes of Finnish adolescents towards Russian minorities. The theoretical framework for this study was the integrated threat theory (ITT). Even though ITT has been revised and threats have been reduced to two major threats (realistic and symbolic threats) (Stephan et al., 2015), this study utilized the original conceptualization of ITT which stipulates that prejudice and negative attitudes towards minorities can be explained by four types of threats that are: realistic threats, symbolic threats, negative stereotyp…

teini-ikäisetRussiansvähemmistötuhatikäryhmätasenteetvarhaisnuoretintegrated threatprejudicemaahanmuuttajatryhmien väliset suhteetvenäläisetennakkoluulotnuoretmaahanmuuttoSuomiadolescentsstereotypiatuhkakuvatFinland
researchProduct

Spin Crossover in Fe(II)–M(II) Cyanoheterobimetallic Frameworks (M = Ni, Pd, Pt) with 2-Substituted Pyrazines

2016

Discovery of spin-crossover (SCO) behavior in the family of Fe(II)-based Hofmann clathrates has led to a "new rush" in the field of bistable molecular materials. To date this class of SCO complexes is represented by several dozens of individual compounds, and areas of their potential application steadily increase. Starting from Fe(2+), square planar tetracyanometalates M(II)(CN)4(2-) (M(II) = Ni, Pd, Pt) and 2-substituted pyrazines Xpz (X = Cl, Me, I) as coligands we obtained a series of nine new Hofmann clathrate-like coordination frameworks. X-ray diffraction reveals that in these complexes Fe(II) ion has a pseudo-octahedral coordination environment supported by four μ4-tetracyanometallat…

tetracyanometalates010405 organic chemistryChemistryStereochemistrypyrazines010402 general chemistry01 natural sciences0104 chemical sciences3. Good healthIonInorganic Chemistrycoordination polymersCrystallographySpin crossoverspin-crossoverMoleculePhysical and Theoretical ChemistryMolecular materialsta116Inorganic Chemistry
researchProduct

N-[3-Methyl-1-phenyl-1-(1H-tetrazol-1-yl)butan-2-yl]acetamide

2016

In the molecule of the title compound, C14H19N5O, the dihedral angle formed between the tetrazole and phenyl rings is 68.39 (4)°. In the crystal, molecules are linked by N—H...N, C—H...N and C—H...O hydrogen bonds to form two-dimensional networks extending parallel to thebcplane.

tetrazolecrystal structureacetamidebiologyChemistryHydrogen bondPlane (geometry)StereochemistryGeneral MedicineCrystal structureDihedral angle010402 general chemistry010403 inorganic & nuclear chemistrybiology.organism_classification01 natural sciences0104 chemical sciencesCrystalchemistry.chemical_compoundCrystallographyhydrogen bondslcsh:QD901-999TetraTetrazolelcsh:CrystallographyAcetamideIUCrData
researchProduct

MTOR inhibitor-based combination therapies for pancreatic cancer

2018

Background: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs further clarification. Methods: We used Mtor floxed mice to analyse the function of the kinase in context of the pancreas at the genetic level. Using a dual-recombinase system, which is based on the flippase-FRT (Flp-FRT) and Cre-loxP recombination technologies, we generated a novel cellular model, allowing the genetic analysis of MTOR functions in tumour maintenance. Cross-species validation and pha…

therapeutic resistance0301 basic medicineCancer ResearchCell SurvivalMAP Kinase Signaling Systempancreatic cancerAntineoplastic AgentsContext (language use)Mechanistic Target of Rapamycin Complex 2mTORC1Mechanistic Target of Rapamycin Complex 1BiologymTORC2BortezomibMice03 medical and health sciencesCell Line TumorPancreatic cancermedicineAnimalsHumansExtracellular Signal-Regulated MAP KinasesMechanistic target of rapamycinPI3K/AKT/mTOR pathwayBenzoxazolesKinaseMTORTOR Serine-Threonine Kinasesmedicine.diseaseddc:3. Good healthPancreatic NeoplasmsPyrimidines030104 developmental biologyOncologybiology.proteinCancer researchCamptothecinTOR Serine-Threonine KinasesPhosphatidylinositol 3-KinaseTranslational TherapeuticsProto-Oncogene Proteins c-aktBiologieCarcinoma Pancreatic Ductal
researchProduct

Tunable Interaction Strength and Nature of the S···Br Halogen Bonds in [(Thione)Br2] Systems

2015

The strength and nature of the S···Br and Br···Br interactions were systematically tuned by altering the electron donor properties of the thione group. Three new halogen-bonded compounds, [(N-methylbenzothiazole-2-thione)Br2]·0.5CH2Cl2 (1), [(2(3H)-benzothiazolethione)Br2] (2), and [(2-benzimidazolethione)Br]·[Br3] (3), were synthesized and studied structurally by using X-ray crystallography and computationally by using charge density analysis based on QTAIM calculations. Analysis of the interaction strength indicated a formation of surprisingly strong S···Br halogen bonds in 1 (−104 kJ mol–1, and RBrS = 0.64) and 2 (−116 kJ mol–1, and RBrS = 0.63) with a substantial covalent contribution. …

thionessynthesis010405 organic chemistryChemistryLigandStereochemistryCharge densityElectron donorGeneral ChemistryInteraction energy010402 general chemistryCondensed Matter Physics01 natural sciencesHeterolysis0104 chemical sciences3. Good healthCrystallographychemistry.chemical_compoundhalogen bondingCovalent bondHalogenMoleculeGeneral Materials Scienceta116bromideCrystal Growth & Design
researchProduct

Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives

2014

A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…

thiopheneVLAK protocolStereochemistryIn silicoCellAntineoplastic AgentsMechanism of actionHeLa CellHeLaAntineoplastic AgentStructure-Activity Relationship3-Benzoylamino-5-imidazol-4-yl-benzo[b]Settore BIO/10 - BiochimicaDrug DiscoverymedicineHumansMoietyComputer SimulationMitosisCell ProliferationPharmacologyAntitumor agentsbiologyDose-Response Relationship DrugMolecular StructureChemistryDrug Discovery3003 Pharmaceutical ScienceMedicine (all)Cell CycleOrganic ChemistryAntitumor agentG2/M phaseGeneral MedicineSettore CHIM/06 - Chimica OrganicaHeLa cell linebiology.organism_classificationSettore CHIM/08 - Chimica Farmaceuticamedicine.anatomical_structureCell cultureSettore CHIM/03 - Chimica Generale E InorganicathiophenesAntimitotic AgentTopoisomerase-II InhibitorDrug Screening Assays AntitumorHeLa CellsHuman
researchProduct

Laskenta-ammattilaisuus Tilisanomat-lehdessä vuosina 2010-2015

2017

Tutkielmassa tutkittiin laskenta-ammattilaisuuden stereotypioita Tilisanomat-lehdessä vuosina 2010—2015. Tutkimusaineistona on lehtiartikkelit, joten tutkimus on kvalitatiivinen. Huomioin tutkimuksessa myös kuvat ja mainokset, mutta pääpaino on artikkeleissa. Tutkimusmenetelmänä käytän sisällönanalyysia ja erityisesti luokittelua. Hyödynnän teoriasidonnaista sisällönanalyysia, eli aloitan luokittelun aineiston perusteella ja lopuksi tarkastelen löytyykö aineistosta pavunlaskijan ja muutosagentin stereotypioita, jotka on tunnistettu aiemmassa tutkimuksessa. Löysin aineistosta runsaasti viitteitä pavunlaskijan ja muutosagentin stereotypioista. Tunnistin myös vartijan ja yrittäjän stereotypiat…

tilintarkastajatkirjanpitäjätammattilaisetlaskentatoimistereotypiatmuutosagentti
researchProduct