Search results for "reparations"

showing 10 items of 367 documents

Occurrence of acidic pharmaceuticals and personal care products in Turia River Basin: From waste to drinking water

2014

The occurrence of 21 acidic pharmaceuticals, including illicit drugs, and personal care products (PPCPs) in waste, surface and drinking water and in sediments of the Turia River Basin (Valencia, Spain) was studied. A liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the determination of these PPCPs with electrospray (ESI) in negative ionization (NI) mode. Ammonium fluoride in the mobile phase improved ionization efficiency by an average increase in peak area of 5 compared to ammonium formate or formic acid. All studied compounds were detected and their concentration was waste water>surface water>drinking water. PPCPs were in waste water treatment plants (WWT…

Environmental EngineeringTriclocarbanCosmeticsWastewaterEnvironmental impact of pharmaceuticals and personal care productsSedimentschemistry.chemical_compoundRiversLC–MS/MSWater Pollution ChemicalDrinking waterEnvironmental ChemistryWaste Management and DisposalEffluentButylparabenMethylparabenSurface waterHydrogen-Ion ConcentrationPollutionPharmaceutical PreparationschemistryWastewaterSpainPharmaceuticals and personal care products (PPCPs)Environmental chemistryWaste waterSurface waterWater Pollutants ChemicalPropylparabenEnvironmental MonitoringScience of The Total Environment
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Emerging technologies for enhanced removal of residual antibiotics from source-separated urine and wastewaters: A review.

2022

Antibiotic residues are of significant concern in the ecosystem because of their capacity to mediate antibiotic resistance development among environmental microbes. This paper reviews recent technologies for the abatement of antibiotics from human urine and wastewaters. Antibiotics are widely distributed in the aquatic environment as a result of the discharge of municipal sewage. Their existence is a cause for worry due to the potential ecological impact (for instance, antibiotic resistance) on bacteria in the background. Numerous contaminants that enter wastewater treatment facilities and the aquatic environment, as a result, go undetected. Sludge can act as a medium for some chemicals to …

Environmental Engineeringconstructed wetlandmicrobial adsorptionbiokemikaalitjätevesiManagement Monitoring Policy and LawWastewaterWaste Disposal FluidantibioticskosteikotSoilAmmoniaHumansWaste Management and DisposalEcosystemvesistötSewageantibiootitWaterGeneral MedicineAnti-Bacterial AgentsbioelectrochemicaljäämätPharmaceutical PreparationsEnvironmental PollutantsbiocharsWater Pollutants ChemicalEnvironmental MonitoringJournal of environmental management
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Swellable microparticles containing Suprofen: evaluation of in vitro release and photochemical behaviour

1998

Suprofen, an anti-inflammatory drug was incorporated in polymer networks based on biocompatible macromolecules, such as alpha,beta-polyasparthydrazide (PAHy) and alpha,beta-poly(N-hydroxyethyl)-DL-aspartamide (PHEA) crosslinked by glutaraldehyde or gamma-rays, respectively. Swelling tests carried out in aqueous media showed that pH value affects the swelling degree of the prepared hydrogels. In vitro release tests were performed in simulated gastrointestinal fluids (pH 1/6.8) using the pH variation method and in phosphate-buffered saline, pH 7.4. Experimental data indicated that Suprofen was released in a sustained way both from PAHy and PHEA microparticles. Further, incorporation of Suprof…

ErythrocytesPlasma SubstitutesSuprofenPharmaceutical ScienceSuprofenHemolysisDosage formchemistry.chemical_compoundmedicineHumansOrganic chemistryParticle SizeActive ingredientGastric JuicePhotosensitizing AgentsChromatographyAnti-Inflammatory Agents Non-SteroidalHydrogen-Ion ConcentrationNylonsCross-Linking ReagentsHydrazineschemistryGlutaralDelayed-Action PreparationsSelf-healing hydrogelsLiberationGlutaraldehydeSwellingmedicine.symptomPeptidesDrug carrierGelsmedicine.drugJournal of Controlled Release
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Medicinal plants and their uses recorded in the Archives of Latvian Folklore from the 19th century.

2020

Abstract Ethnopharmacological relevance The records of folk medicine present historical evidence of medicinal plant usage in the territory of Latvia and describe native and imported plants and plant products that were used as medicine. Aim of the study To collect and analyse the ethnobotanical knowledge found in records of Latvian folk medicine available in the Archives of Latvian Folklore. Materials and methods Following the International Classification of Primary Care, plant uses were grouped into one of the 17 categories based on the body systems and psychological and social problems. Each plant was identified by its scientific name according to The Plant List website. Additionally, the …

Ethnobotany03 medical and health sciencesHerbal tea0302 clinical medicineDrug Discoverymedia_common.cataloged_instanceHumansEuropean unionMedicinal plantsFolklore030304 developmental biologymedia_commonPharmacology0303 health sciencesAchillea millefoliumPlants MedicinalTraditional medicineHistory 19th CenturyNative plantLatviaGeography030220 oncology & carcinogenesisEthnobotanyArtemisia absinthiumMedicine TraditionalPlant PreparationsEthnomedicineJournal of ethnopharmacology
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LABA/LAMA fixed-dose combinations in patients with COPD: A systematic review

2018

Paola Rogliani,1 Luigino Calzetta,1 Fulvio Braido,2 Mario Cazzola,1 Enrico Clini,3 Girolamo Pelaia,4 Andrea Rossi,5 Nicola Scichilone,6 Fabiano Di Marco7 1Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Rome, Italy; 2Department of Internal Medicine, IRCCS San Martino Genoa University Hospital, Genoa, Italy; 3Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, Modena, Italy; 4Department of Medical and Surgical Sciences, Section of Respiratory Diseases, Magna Græcia University, Catanzaro, Italy; 5Pulmonary Unit, University of Verona, Verona, Italy; 6Department of Internal Medicine, University of Palermo, Palermo, Italy; 7…

ExacerbationReviewQuinoloneslaw.inventionPulmonary Disease Chronic Obstructivechemistry.chemical_compound0302 clinical medicineRandomized controlled trialsystematic reviewlaw030212 general & internal medicineCOPDLABA LAMA fixed-dose combination COPD systematic reviewbiologyHealth PolicyOlodaterolLAMAGeneral MedicineLamaRespiratory Function Testsfixed-dose combinationDrug CombinationsTreatment OutcomeIndanssystematic review.hormones hormone substitutes and hormone antagonistsmedicine.drugPulmonary and Respiratory Medicinemedicine.medical_specialtyFixed-dose combinationLABA; LAMA; fixed-dose combination; COPD; systematic reviewLABAMuscarinic AntagonistsSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicinemedicineHumansCOPDAdverse effectAdrenergic beta-2 Receptor Agonistslcsh:RC705-779business.industryPublic Health Environmental and Occupational Healthlcsh:Diseases of the respiratory systemCOPD; LABA; LAMA; fixed-dose combination; systematic reviewmedicine.diseasebiology.organism_classificationGlycopyrrolate030228 respiratory systemchemistryDelayed-Action PreparationsIndacaterolbusiness
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Implementation and microbiological stability of dose-banded ganciclovir infusion bags prepared in series by a robotic system.

2018

Objectives The implementation of dose-banding (DB) in centralised, pharmacy-based cytotoxic drug preparation units allows the preparation of standardised doses in series. The aim of this study was to evaluate the feasibility of DB for the prescribing of ganciclovir (GV) infusion solutions and to investigate the microbiological stability of dose-banded, automatically prepared ready-to-administer GV infusion bags by media-fill simulation tests and sterility tests. Methods The frequency of prescription of GV doses was retrospectively analysed before and after implementing the DB scheme. Four dose-ranges or ‘bands’ and the corresponding standard doses (250, 300, 350, 400 mg) were identified. Th…

GanciclovirCytotoxic drugSterilityDrug CompoundingDrug StorageGrowth promotion030226 pharmacology & pharmacyAntiviral AgentsStandard PreparationsExtended storage03 medical and health sciences0302 clinical medicineAnimal scienceDrug StabilityRefrigerationMedicineInfusions Parenteral030212 general & internal medicineGeneral Pharmacology Toxicology and PharmaceuticsGanciclovirDrug PackagingRetrospective StudiesOriginal Researchbusiness.industryReproducibility of ResultsRoboticsRobotic systemsAseptic processingbusinessDrug ContaminationPharmacy Service Hospitalmedicine.drugEuropean journal of hospital pharmacy : science and practice
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Estrogenic effects of food wrap packaging xenoestrogens and flavonoids in female Wistar rats : a comparative study

2003

International audience; The objective of this study was to compare the estrogenicity of xenoestrogens found in food wrap packaging and phytoestrogen flavonoids. Uterotrophic and vaginal cornification assays were performed on immature and ovariectomized rats. Genistein, bisphenol F, and octylphenol were identified as estrogenic only in immature rats. Using vaginal cornification as a more specific estrogenic parameter, all tested compounds except tangeretin were active in immature rats. While apigenin and kaempferol appeared to have low estrogenic activity, they potentialized the uterotrophic effect of 17β-estradiol in immature rats. These data showed that (i) phytoestrogens like genistein ca…

Genistein010501 environmental sciencesToxicology01 natural scienceschemistry.chemical_compound[SDV.IDA]Life Sciences [q-bio]/Food engineering0303 health sciencesIMMATURE RATSEstradiolMolecular Structurefood and beveragesOrgan SizePHYTOESTROGENS[SDV.IDA] Life Sciences [q-bio]/Food engineeringVAGINAL CORNIFICATIONVaginaApigeninToxicityOvariectomized ratFemalehormones hormone substitutes and hormone antagonistsmedicine.medical_specialtymedicine.drug_class[SPI.GPROC] Engineering Sciences [physics]/Chemical and Process EngineeringOvariectomyXENOESTROGENSBiologySensitivity and Specificity03 medical and health sciencesPredictive Value of TestsIn vivoInternal medicinemedicineAnimals[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringEstrogens Non-SteroidalRats Wistar030304 developmental biology0105 earth and related environmental sciencesFlavonoidsDose-Response Relationship DrugOVARIECTOMIZED RATSUterusEstrogensUTEROTROPHIC ASSAYIsoflavonesRatsEndocrinologychemistryEstrogenPhytoestrogensPlant PreparationsKaempferol
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Determination of pharmaceuticals in soils and sediments by pressurized liquid extraction and liquid chromatography tandem mass spectrometry

2010

13 páginas, 4 figuras, 6 tablas.

Geologic SedimentsElectrosprayTandem mass spectrometryLiquid chromatographyChemical FractionationTandem mass spectrometrySensitivity and SpecificityBiochemistryHigh-performance liquid chromatographyAnalytical ChemistryMatrix (chemical analysis)SoilLiquid chromatography–mass spectrometryAntibioticsSoil PollutantsSample preparationSolid phase extractionEnvironmental analysisSolid-phase extractionChromatographyChemistryOrganic ChemistryExtraction (chemistry)Reproducibility of ResultsGeneral MedicineMulti-residue methodPharmaceutical PreparationsLinear ModelsPharmaceuticalsSedimentChromatography Liquid
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Pharmaceuticals in settleable particulate material in urban and non-urban waters

2011

Abstract Wastewater treatment plants (WWTP) are important sources of settleable particulate material (SPM), heading to sediments with natural suspended solids. To date, there is little information about the fate of pharmaceuticals in sediment systems. In this study, the objective was to determine if pharmaceuticals are detected in SPM at locations near WWTPs or even in rural areas, thus being susceptible for sedimentation. SPM samples were collected from 10 sites in Finland, grouped as reference, rural and wastewater effluent sites. SPM collectors were placed about 35 cm above bottom for about 2 months during summer. After extraction, a set of 17 pharmaceuticals was analyzed. Several pharma…

Geologic SedimentsEnvironmental EngineeringHealth Toxicology and Mutagenesista1172Waste Disposal FluidParticulate materialEnvironmental ChemistryEffluentFinlandSuspended solidsfungiPublic Health Environmental and Occupational HealthEnvironmental engineeringWaterSedimentGeneral MedicineGeneral ChemistrySedimentationPollutionPharmaceutical PreparationsWastewaterEnvironmental chemistryEnvironmental scienceSewage treatmentWater Pollutants ChemicalEnvironmental MonitoringChemosphere
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Risk assessment on the presence of pharmaceuticals in sediments, soils and waters of the Pego-Oliva Marshlands (Valencia, eastern Spain).

2012

9 páginas, 3 figuras, 2 tablas.

Geologic SedimentsEnvironmental EngineeringSoil testGeologic SedimentsRisk AssessmentSoilTap waterTandem Mass SpectrometryEnvironmental ChemistryAnimalsSoil PollutantsWaste Management and DisposalGroundwaterRisk assessmentHydrologyPrincipal Component AnalysisDrinking WaterSolid Phase ExtractionFishesSedimentSurface waterPollutionPharmaceutical PreparationsSpainEnvironmental chemistryWetlandsSoil waterPharmaceuticalsSoil horizonEnvironmental scienceSedimentMediterranean wetlandsSurface waterGroundwaterWater Pollutants ChemicalChromatography LiquidThe Science of the total environment
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