Search results for "report"
showing 10 items of 2364 documents
Expression of a reporter gene is reduced by a ribozyme in transgenic plants
1994
A chimeric gene encoding a ribozyme under the control of the cauliflower mosaic virus (CaMV) 35S promoter was introduced into transgenic tobacco plants. In vivo activity of this ribozyme, which was designed to cleave npt mRNA, was previously demonstrated by transient expression assays in plant protoplasts. The ribozyme gene was transferred into transgenic tobacco plants expressing an rbcS-npt chimeric gene as an indicator. Five double transformants out of sixteen exhibited a reduction in the amount of active NPT enzyme. To measure the amount of ribozyme produced, in the absence of its target, the ribozyme and target genes were separated by genetic segregation. The steady-state concentration…
La transgresión de la realidad en el reportaje televisivo : El tratamiento del caso “El Cabanyal”
2009
En esta comunicación se parte, como supuesto previo, de que la lógica económica que define la estructura y dinámica del sistema de la comunicación global y local determina el tratamiento y la construcción de la realidad social en el conjunto de discursos que se construyen en los diferentes medios de comunicación. En este caso, el objeto de estudio es, precisamente, constatar que, como efecto relevante de la lógica dominante citada, la construcción discursiva audiovisual del programa de Cuatro Callejeros se lleva a cabo trasgrediendo la realidad social que pretende trasmitir, “la cotidianidad del barrio del Cabanyal en Valencia” y convirtiéndola en espectáculo persuasivo para consumidores en…
Intorno allo Stato da Mar: il viaggio del bailo Giorgio Giustinian da Costantinopoli a Venezia (1627)
2023
Presentation and analysis of the Relazione (Report) on the return voyage of Giorgio Giustinian, Bailo of Constantinople (1627), of particular interest due to the exceptional nature of the itinerary followed, which progressed into Macedonia and Serbia as far as Sofia and Belgrade and then turned towards Sarajevo, Mostar and reached Spalato. The document allows us to add an important element to the voyage reports between Venice and Constantinople, at the moment when the difficult relations between the Most Serene Republic and the Ottoman Empire seemed having found a new balance at the expense of the Republic of Ragusa. The unpublished Relazione is provided in the Appendix.
Crystal structure of μ-oxido-1,1′κ2 O:O-bis{tetra-μ-oxido-1:2κ2 O:O;1:3κ2 O:O;2:3κ4 O:O-tris[1,2,3(η5)-pentamethylcyclopentadienyl]-trianglo-tri…
2015
The title polynuclear organometallic titanium(IV) oxide, [{Ti3(η5-C5Me5)3(μ-O)4}2(μ-O)], exhibits two Ti3O4 cores bridged by an O atom located on a twofold axis. All metal centers present the typical three-legged piano-stool coordination environment, where one site is occupied by a pentamethylcyclopentadienyl ligand linked in an η5-coordination fashion, while three bridging O atoms fill the other three sites.
Are long-haul truck drivers unusually alert? A comparison with long-haul airline pilots.
2020
Abstract Background Recent studies suggest heavy vehicle drivers self-estimate their sleepiness unexpectedly low during night duties. The present study compared sleepiness ratings of long-haul truck drivers with those of long-haul airline pilots during night and non-night duties. In addition, the correspondence between self-rated manifest and predicted latent sleepiness was examined in the two groups. Methods Twenty-two drivers and 33 pilots participated. Their working hours, sleep, on-duty sleepiness, and use of sleepiness countermeasures were measured in naturalistic conditions. Predictions of latent sleepiness were based on the measurements of working hours and sleep using the Sleep/Wake…
Capturing colorectal cancer inter-tumor heterogeneity in patient-derived xenograft (PDX) models
2019
Patient‐derived xenograft (PDX) models have become an important asset in translational cancer research. However, to provide a robust preclinical platform, PDXs need to accommodate the tumor heterogeneity that is observed in patients. Colorectal cancer (CRC) can be stratified into four consensus molecular subtypes (CMS) with distinct biological and clinical features. Surprisingly, using a set of CRC patients, we revealed the partial representation of tumor heterogeneity in PDX models. The epithelial subtypes, the largest subgroups of CRC subtype, were very ineffective in establishing PDXs, indicating the need for further optimization to develop an effective personalized therapeutic approach …
Cathepsin D Content in Colorectal Cancer
1995
Cathepsin D content and activity were determined in matched paired sets of colorectal tumor tissue and normal mucosa and correlated with a number of biological and clinical parameters. Significantly higher cathepsin D activity was measured in tumor cytosol compared to paired normal mucosa (p < 0.02), in Dukes’ stage A tumors compared to Dukes’ B and C (p < 0.05), in tumors < 5 cm compared to those > 5 cm, or in tumors with a low proliferation rate compared to those with a high proliferation rate (p < 0.05). Moreover, significant differences in enzyme activity between tumor tissue and paired normal mucosa were observed in node-positive and G2 tumors (p < 0.05). No significa…
Migration d'images et icônes de la mémoire : l'apport de la guerre d'Espagne
2011
En somme, la guerre d'Espagne apparaît comme le théâtre d'un équilibre précaire et paradoxal : les photographes et les opérateurs tournent leur regard vers la population civile, la prennent en mouvement grâce aux nouvelles techniques, à cause aussi, si 1'on veut, du chaos que le conflit entraîna sur le destin de ces non-combattants. Ils ont pu certainement éprouver des expériences inhumaines, mais le regard qui les observe les humanise en quelque sorte, meme (surtout) dans la douleur. Ce sera, oserais-je le dire, la dernière fois. C'est peut-être la raison pour laquelle a pu s'installer ce lieu commun qui voit la guerre d'Espagne comme la dernière guerre photogénique.
von Hippel-Lindau Protein-Mediated Repression of Tumor Necrosis Factor Alpha Translation Revealed through Use of cDNA Arrays
2003
Based on evidence that the von Hippel-Lindau (VHL) tumor suppressor protein is associated with polysomes and interacts with translation regulatory factors, we set out to investigate the potential influence of pVHL on protein translation. To this end, renal cell carcinoma (RCC) cells that either lacked pVHL or expressed pVHL through stable transfection were used to prepare RNA from cytosolic (unbound) and polysome-bound fractions. Hybridization of cDNA arrays using RNA from each fraction revealed a subset of transcripts whose abundance in polysomes decreased when pVHL function was restored. The tumor necrosis factor alpha (TNF-alpha) mRNA was identified as one of the transcripts that prefere…
Impact of freezing rate on electrical conductivity of produce
2013
The aim of this work was to compare the effects of freezing rate on electrical conductivity of potatoes, carrots and apples. Electrical conductivity tests were conducted on a custom ohmic cell while samples texture was measured by means of a universal testing machine. The raw un-pretreated samples were used as control. This study showed that freezing pre-treatments lead to differences in electrical conductivity of considered samples, producing structural damage, the latter being relatively more severe when the tested products undergo ohmic treatment.