Search results for "report"

showing 10 items of 2364 documents

Psychometric Properties of Spanish Version Student Utrecht Work Engagement Scale (UWES–S–9) in High-school Students

2019

AbstractThe Utrecht Work Engagement Scale (UWES) is a self-report instrument widely used, both in the original and its abbreviated version of nine items, to assess the work -UWES, UWES–9– and academic engagement -UWES-S, UWES–S–9–. The present study examines factor structure of the UWES–S–9 using confirmatory factor analysis (CFA), its convergent validity and invariance across sex and age groups in a sample of 626 Spanish high school students. The results support an unidimensional conceptualization of engagement (S-Bχ2/df = 5.29; CFI = .96; NNFI = .94; RMSEA = .083; IFI = .96; AIC = 82.21; BIC = 267.38), revealed an essentially invariant structure of the UWES–S–9 across the sex, ΔS-Bχ2(Δ6) …

MaleLinguistics and LanguageAdolescentPsychometrics050109 social psychologyStudent engagementPersonal SatisfactionFactor structureLanguage and LinguisticsStructural equation modelingAge groups0502 economics and businessHumans0501 psychology and cognitive sciencesStudentsGeneral PsychologyOptimismAcademic SuccessWork engagement05 social sciencesReproducibility of ResultsSpanish versionWork EngagementConfirmatory factor analysisConvergent validityFemaleSelf ReportFactor Analysis StatisticalPsychologyStress Psychological050203 business & managementClinical psychologyThe Spanish Journal of Psychology
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The SF-8 Spanish Version for Health-Related Quality of Life Assessment: Psychometric Study with IRT and CFA Models.

2018

AbstractThe aim of current research is to analyze the psychometric properties of the Spanish version of the SF–8, overcoming previous shortcomings. A double line of analyses was used: competitivestructural equations modelsto establish factorial validity, andItem Response theoryto analyze item psychometric characteristics and information. 593 people aged 60 years or older, attending long life learning programs at the University were surveyed. Their age ranged from 60 to 92 years old. 67.6% were women. The survey included scales on personality dimensions, attitudes, perceptions, and behaviors related to aging. Competitive confirmatory models pointed out two-factors (physical and mental health…

MaleLinguistics and LanguagePsychometricsmedia_common.quotation_subjectLogistic regressionLanguage and LinguisticsStructural equation modeling03 medical and health sciences0302 clinical medicinePerceptionItem response theoryPersonalityHumans030212 general & internal medicinePatient Reported Outcome MeasuresGeneral Psychologymedia_commonAgedAged 80 and over030505 public healthModels StatisticalSpanish versionMiddle AgedMental healthTest (assessment)SpainQuality of LifeFemale0305 other medical sciencePsychologyClinical psychologyThe Spanish journal of psychology
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Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis

2012

Many disorders are associated with altered serum protein concentrations, including malnutrition, cancer, and cardiovascular, kidney, and inflammatory diseases. Although these protein concentrations are highly heritable, relatively little is known about their underlying genetic determinants. Through transethnic meta-analysis of European-ancestry and Japanese genome-wide association studies, we identified six loci at genome-wide significance (p −8 ) for serum albumin ( HPN-SCN1B , GCKR-FNDC4 , SERPINF2-WDR81 , TNFRSF11A-ZCCHC2 , FRMD5-WDR76 , and RPS11-FCGRT , in up to 53,190 European-ancestry and 9,380 Japanese individuals) and three loci for total protein ( TNFRS13B , 6q21.3, and ELL2 , in …

MaleLinkage disequilibriumGenome-wide association studyDETERMINANTSLinkage DisequilibriumMiceGenetics(clinical)POPULATIONGenetics (clinical)SNPSRISKGeneticseducation.field_of_studybiologyChromosome MappingBlood ProteinsIDENTIFYMiddle AgedFemaleAdultPopulationSerum albuminserum protein; albumin; GWASSingle-nucleotide polymorphismLocus (genetics)ALBUMINWhite PeopleAsian PeopleGene mappingSDG 3 - Good Health and Well-beingReportBIOCHEMICAL TRAITSFC-RECEPTORGeneticsAnimalsHumansGenetic Predisposition to DiseaseSMOKING-BEHAVIORddc:610GENOME-WIDE ASSOCIATIONeducationAllelesSerum AlbuminAgedGenetic associationGenetic LociProtein BiosynthesisProteolysisbiology.proteinRibosomesGenome-Wide Association StudyThe American Journal of Human Genetics
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DVWA gene polymorphisms and osteoarthritis

2015

Background: Osteoarthritis (OA) is a degenerative joints disorder influenced by genetic predisposition. We reported that rs11718863 DVWA SNP was represented in Sicilian with a more severe Kellgren and Lawrence (KL) radiographic grade, displaying its predictive role as OA marker progression. Here, we describe the DVWA SNPs: rs11718863, rs7639618, rs7651842, rs7639807 and rs17040821 probably able to induce protein functional changes. Findings: Sixty-one Sicilian patients with knee OA and 100 healthy subjects were enrolled. Clinical and radiographic evaluation was performed using AKSS scores and KL. Linkage Disequilibrium (LD) analyses were performed in order to verify whether the SNPs segrega…

MaleLinkage disequilibriumShort ReportSingle-nucleotide polymorphismOsteoarthritisCollagen Type VIBioinformaticsPolymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologyLinkage DisequilibriumWhite PeopleGene FrequencyOsteoarthritisHaplotypeGenetic predispositionDVWAMedicineSNPHumansGenetic Predisposition to DiseaseAlleleOsteoarthritis DVWA Single nucleotide polymorphisms Haplotypes KLAllele frequencySicilyAllelesAgedMedicine(all)Aged 80 and overBiochemistry Genetics and Molecular Biology(all)business.industryHaplotypeHomozygoteGeneral MedicineSingle nucleotide polymorphismsMiddle AgedOsteoarthritis Kneemedicine.diseaseSingle nucleotide polymorphismKLHaplotypesOsteoarthritiFemalebusinessPseudogenesBMC Research Notes
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Identifying Genetic Traces of Historical Expansions: Phoenician Footprints in the Mediterranean

2008

10 páginas, 1 figura, 4 páginas.-- et al.

MaleMediterranean climatePopulation DynamicsPopulationHomelandBiologyPolymorphism Single NucleotideHaplogroup03 medical and health sciencesMediterranean seaGene FrequencyReportEthnicityMediterranean SeaGeneticsHumansAnalytical strategyGenetics(clinical)educationAllelesHistory AncientGenetics (clinical)Historical record030304 developmental biologyGenetics0303 health scienceseducation.field_of_studyChromosomes Human YGeography030305 genetics & heredityEmigration and Immigrationlanguage.human_languageGenealogyGenetics PopulationHaplotypeslanguagePhoenician
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Use of platelet concentrate gel in second-intention wound healing: a case report.

2021

Abstract Background Wound healing is a complex and dynamic process. Healing of acute and chronic wounds can be impaired by patient factors (that is, comorbidities) and/or wound factors (that is, infection). Regenerative medicine products, such as autologous/homologous platelet-rich plasma gel, may speed up the healing process. Autologous/homologous platelet-rich plasma is an advanced wound therapy used for hard-to-heal acute and chronic wounds. The cytokines and growth factors contained in platelet-rich plasma play a crucial role in the healing process. Case presentation A 61-year-old Caucasian male patient, suffering from mental retardation following meningitis, with a transplanted kidney …

MaleMethicillin-Resistant Staphylococcus aureusmedicine.medical_specialtymedicine.drug_classmedicine.medical_treatmentFistulaArteriovenous fistulalcsh:MedicineCase ReportIntention030204 cardiovascular system & hematology030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineAntisepticSurgical oncologymedicineHumansWound Healingintegumentary systembusiness.industryPlatelet-Rich Plasmalcsh:RGranulation tissueGeneral MedicineMiddle Agedmedicine.diseaseSurgerymedicine.anatomical_structureAmputationRegenerative medicineQuality of LifeSkin flapSurgeryWound healingbusinessMeningitisJournal of medical case reports
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Isolation and characterization of Bartonella quintana from parotid gland of an immunocompetent man.

2009

We describe a case of the isolation of Bartonella quintana from the parotid gland of an apparently healthy man. Pathological examination showed intraparotid granulomatous abscessual lymphadenitis. Diagnosis was made on the basis of high titers of immunoglobulin G (IgG) and IgM antibodies and of culture isolation of a causative agent from parotid aspirate.

MaleMicrobiology (medical)Pathologymedicine.medical_specialtyIgm antibodyAnti-Inflammatory AgentsCase ReportsImmunoglobulin GMicrobiologyB. quintanastomatognathic systemBartonella quintanaLymphadenitismedicineHumansbiologyMiddle Agedbacterial infections and mycosesbiology.organism_classificationmedicine.diseaseIsolation (microbiology)Antibodies BacterialTrench FeverB. quintana; parotid glandTrench feverAnti-Bacterial AgentsParotid glandstomatognathic diseasesmedicine.anatomical_structureImmunoglobulin MImmunoglobulin MImmunoglobulin Gbiology.proteinbacteriaBartonella quintanaSteroidsParotid DiseasesParotid Diseasesparotid gland
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Persistent Legionella Infection in a Patient after Bone Marrow Transplantation

2000

ABSTRACT We report on a patient who developed Legionella pneumonia after bone marrow transplantation. Despite appropriate antibiotic treatment, disease progressed. The patient developed a lung abscess from which Legionella and Prevotella were isolated. Cure was achieved by surgical resection. The resected material was sterile, but 16S ribosomal DNA analysis revealed Legionella DNA.

MaleMicrobiology (medical)medicine.medical_specialtyPathologyLegionellaLegionella PneumoniaLung abscessCase ReportsLegionella pneumophilaLegionella pneumophilamedicineHumansLung AbscessAbscessBone Marrow Transplantationbiologybusiness.industryMiddle Agedbacterial infections and mycosesmedicine.diseasebiology.organism_classificationrespiratory tract diseasesSurgeryPneumoniamedicine.anatomical_structurebacteriaLegionnaires' diseaseBone marrowLegionnaires' DiseasebusinessJournal of Clinical Microbiology
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Key features and clinical variability of COG6-CDG

2015

The conserved oligomeric Golgi (COG) complex consists of eight subunits and plays a crucial role in Golgi trafficking and positioning of glycosylation enzymes. Mutations in all COG subunits, except subunit 3, have been detected in patients with congenital disorders of glycosylation (CDG) of variable severity. So far, 3 families with a total of 10 individuals with biallelic COG6 mutations have been described, showing a broad clinical spectrum. Here we present 7 additional patients with 4 novel COG6 mutations. In spite of clinical variability, we delineate the core features of COG6-CDG i.e. liver involvement (9/10), microcephaly (8/10), developmental disability (8/10), recurrent infections (7…

MaleMicrocephalyGlycosylationAdolescentEndocrinology Diabetes and MetabolismProtein subunitHyperkeratosisMolecular Sequence DataGolgi ApparatusCase ReportsResearch SupportBiochemistryConserved oligomeric Golgi complexYoung AdultEndocrinologyCogCongenital Disorders of GlycosylationGeneticsJournal ArticleMedicineHumansNon-U.S. Gov'tChildMolecular BiologyExome sequencingGenetic Association StudiesGeneticsbusiness.industryConserved oligomeric Golgi complexResearch Support Non-U.S. Gov'tHigh-Throughput Nucleotide SequencingInfantCongenital disorder of glycosylationmedicine.diseasePhenotypeAdaptor Proteins Vesicular TransportPhenotypeCOG6MutationMicrocephalyFemaleCDGbusinessCongenital disorder of glycosylation
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In-Frame Mutations in Exon 1 of SKI Cause Dominant Shprintzen-Goldberg Syndrome

2012

International audience; Shprintzen-Goldberg syndrome (SGS) is characterized by severe marfanoid habitus, intellectual disability, camptodactyly, typical facial dysmorphism, and craniosynostosis. Using family-based exome sequencing, we identified a dominantly inherited heterozygous in-frame deletion in exon 1 of SKI. Direct sequencing of SKI further identified one overlapping heterozygous in-frame deletion and ten heterozygous missense mutations affecting recurrent residues in 18 of the 19 individuals screened for SGS; these individuals included one family affected by somatic mosaicism. All mutations were located in a restricted area of exon 1, within the R-SMAD binding domain of SKI. No mut…

MaleModels Molecularmedicine.disease_cause[SDV.BBM.BM] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyMarfan SyndromeArachnodactylyExon0302 clinical medicineGene OrderMissense mutationGenetics(clinical)Child[ SDV.GEN.GH ] Life Sciences [q-bio]/Genetics/Human geneticsGenetics (clinical)Exome sequencingGenes DominantGenetics0303 health sciencesMutationShprintzen–Goldberg syndromeExonsPhenotypePedigreeDNA-Binding ProteinsPhenotypeChild PreschoolFemalemedicine.symptomAdultAdolescentMolecular Sequence Data[ SDV.BBM.BM ] Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologyBiology[SDV.GEN.GH] Life Sciences [q-bio]/Genetics/Human genetics03 medical and health sciencesCamptodactylyCraniosynostosesYoung Adultstomatognathic systemReportProto-Oncogene ProteinsmedicineGeneticsHumansAmino Acid Sequence030304 developmental biologyFacies[SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry Molecular Biology/Molecular biologymedicine.diseaseMolecular biologyProtein Structure TertiaryArachnodactyly[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsMutationSequence Alignmenthuman activities030217 neurology & neurosurgery
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