Search results for "restrict"

Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: system…

2020

This systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: −4.83 kg, 95%-CI: −5.46, −4.21; n = 6 RCTs), wais…

Study of the mechanisms of oxidative stress, mitochondrial function and endoplasmic reticulum stress in obesity. Role in subclinical atherosclerosis …

2019

El aumento alarmante de la prevalencia de obesidad a nivel mundial y la enorme carga de enfermedad asociada ha generado una creciente demanda de estrategias para frenar la epidemia y / o mitigar los efectos dañinos de la obesidad sobre la salud. Para ello se requiere un compromiso firme y sinérgico por parte de todas las fuerzas sociales, no sólo para desarrollar estrategias preventivas, sino también para contribuir al conocimiento de los eventos patológicos y los mecanismos involucrados en el desarrollo de esta enfermedad. Por ello, el objetivo principal de la presente tesis doctoral es profundizar en los mecanismos subyacentes de la obesidad, especialmente en aquellos relacionados con el …

Comparison between unrestricted dynamic shakedown design and a new probabilistic approach for structures under seismic loadings

2014

The paper concerns a study related to the comparison between two different approaches utilized for the formulation of an optimal shakedown design problem for elastic plastic frame structures subjected to a combination of fixed and seismic loading. The first formulation utilizes the unrestricted dynamic shakedown theory, while the second one is based on a new probabilistic approach. The comparison is effected in terms of mathematical formulations, in terms of adopted loading models and in terms of numerical results. The performed applications are related to plane steel frames.

Intron variants of the p53 gene are associated with increased risk for ovarian cancer but not in carriers of BRCA1 or BRCA2 germline mutations

1999

Two biallelic polymorphisms in introns 3 and 6 of the p53 gene were analysed for a possible risk-modifying effect for ovarian cancer. Germline DNA was genotyped from 310 German Caucasian ovarian cancer patients and 364 healthy controls. We also typed 124 affected and 276 unaffected female carriers with known deleterious BRCA1 or BRCA2 germline mutation from high-risk breast-ovarian cancer families. Genotyping was based on PCR and high-resolution gel electrophoresis. German ovarian cancer patients who carried the rare allele of the MspI restriction fragment length polymorphism (RELP) in intron 6 were found to have an overall 1.93-fold increased risk (95% confidence internal (CI) 1.27–2.91) w…

El impacto de la política de visados sobre los flujos internacionales de turistas: Un análisis con datos de panel

2016

Using newly panel data on visa restrictions for the years 2000 and 2010 in a theory-grounded gravity model, we find a robust, causal negative impact of visa restrictions on international tourist flows. By destination, the detrimental impact of this type of barrier is observed for tourists going to developing countries (with the exception of East and South Asia), but not for those to developed ones. By country of origin of tourists, the impact of visa restrictions appears to be the same for tourists coming from developed and developing countries. These findings have important consequences in policy terms for tourism management at a regional level.

Parental Resources in Parents of Children with Special Needs (SNs) at the Time of COVID-19

2023

Background. The limitations imposed by governments for containing the spread of COVID-19 have affected familial relationships, especially those of families dealing with children with special needs or chronic illness conditions. The current study aims to better understand what pathological/disability condition has impacted parental resources, sense of competence, and perception of children’s executive functioning the most. Methods. A sample of 648 parents was asked to answer a survey assessing children’s condition (typical development, specific learning disorder, autism spectrum syndrome, chronic illness), parental resources, parenting sense of competence (distinguished into pare…

Nowe zachowania ryzykowne młodzieży - charakterystyka i tendencje rozwoju

2017

Too much? Excessive sexual experiences in bisexual women’s life stories

2017

This article explores bisexual women’s sexual experiences at the edges of or between relationships. It draws on the follow-up interviews of a longitudinal interview set conducted in 2005 and 2014–2015 with bisexual women and their partners, who do not identify as bisexuals. Bisexual women’s spontaneous, detailed and affective narrations of sexual experiences in the follow-up interviews caught the author’s attention. Although the experiences were often narrated as pleasurable, they could be overwhelming, and women also expressed concern that they were excessive, “too much”. The analysis of the women’s accounts utilizes and develops a psychosocial concept of excess. It reveals that the excess…

Intellectual Property Rights: An Economic Approach

2014

Abstract This paper aims to analyse the intellectual property rights from an economic perspective. The paper is discussing the points of view of well known economists in relation to the positive and negative impacts of the intellectual property systems. It brings also into discussion the role of IPR as a barrier to entry and a mean to restrict competition and to favour monopoly situations.

Effects of states governments restrictions related on Coronavirus disease (COVID-19) on states economy - comparison of Baltic States, Sweden, and Bel…

2021

In order to limit the spread of COVID-19, states have gradually implemented restrictions mandating school and kindergarten closures, postponing academic semesters and prohibiting visits to nursing homes to protect the elderly, borders were closed, states prohibited physical contact with more than one person from outside one's household, and other restrictions. This paper examines the economic effects of policies to contain Covid-19 in Baltic States by comparing they with experience of Sweden and Belarus where approach was less stringent and based more on social responsibility than legal obligations compared to the other European states