Search results for "restrict"

Cytotoxic necrotizing factor type 2 produced by virulent Escherichia coli modifies the small GTP-binding proteins Rho involved in assembly of actin s…

1994

Cytotoxic necrotizing factor type 2 (CNF2) produced by Escherichia coli strains isolated from intestinal and extraintestinal infections is a dermonecrotic toxin of 110 kDa. We cloned the CNF2 gene from a large plasmid carried by an Escherichia coli strain isolated from a lamb with septicemia. Hydropathy analysis of the deduced amino acid sequence revealed a largely hydrophilic protein with two potential hydrophobic transmembrane domains. The N-terminal half of CNF2 showed striking homology (27% identity and 80% conserved residues) to the N-terminal portion of Pasteurella multocida toxin. Methylamine protection experiments and immunofluorescence studies suggested that CNF2 enters the cytosol…

Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety

2020

Kritische Anmerkungen zur H/B-Dreiteilung Vorgangspassiv - Zustandspassiv - allgemeine Zustandsform

2004

Intergenerational fitness effects of the early life environment in a wild rodent

2019

The early life environment can have profound, long‐lasting effects on an individual's fitness. For example, early life quality might (a) positively associate with fitness (a silver spoon effect), (b) stimulate a predictive adaptive response (by adjusting the phenotype to the quality of the environment to maximize fitness) or (c) be obscured by subsequent plasticity. Potentially, the effects of the early life environment can persist beyond one generation, though the intergenerational plasticity on fitness traits of a subsequent generation is unclear. To study both intra‐ and intergenerational effects of the early life environment, we exposed a first generation of bank voles to two early life…

Early life of fathers affects offspring fitness in a wild rodent

2019

Intergenerational fitness effects on offspring due to the early life of the parent are well studied from the standpoint of the maternal environment, but intergenerational effects owing to the paternal early life environment are often overlooked. Nonetheless, recent laboratory studies in mammals and ecologically relevant studies in invertebrates predict that paternal effects can have a major impact on the offspring's phenotype. These non‐genetic, environment‐dependent paternal effects provide a mechanism for fathers to transmit environmental information to their offspring, and could allow rapid adaptation. We used the bank vole Myodes glareolus, a wild rodent species with no paternal care, t…

Coronavirus-related health literacy and perceived restrictiveness of protective measures among community-dwelling older persons in Finland

2021

Abstract Background Older people with limited health literacy may encounter difficulties in finding relevant information on COVID-19, understanding its relevance, and complying with recommended protective measures. Complying with such recommendations has required older as well as younger persons to change their daily lives in ways that have reduced their opportunities for engaging in many activities meaningful to them. Aims To find out from what sources older people have obtained information on protective measures, the level of their coronavirus-related health literacy (CHL), and whether CHL is associated with their perceptions of the restrictiveness of coronavirus-related protective measur…

Physiological and autonomic stress responses after prolonged sleep restriction and subsequent recovery sleep in healthy young men

2018

Purpose Sleep restriction is increasingly common and associated with the development of health problems. We investigated how the neuroendocrine stress systems respond to prolonged sleep restriction and subsequent recovery sleep in healthy young men. Methods After two baseline (BL) nights of 8 h time in bed (TIB), TIB was restricted to 4 h per night for five nights (sleep restriction, SR, n = 15), followed by three recovery nights (REC) of 8 h TIB, representing a busy workweek and a recovery weekend. The control group (n = 8) had 8 h TIB throughout the experiment. A variety of autonomic cardiovascular parameters, together with salivary neuropeptide Y (NPY) and cortisol levels, were assessed.…

Contraintes et libertés textuelles

2006

The article starts from a conception of language according to which the semiotic units that speakers use do not emanate from individual mental processes but from the socialization of representation instruments which, being individual elements initially, have later been involved in processes of communicative circulation. In the same way that, in each language, verbal uses are limited by a series of restrictions in the constitution of some phonic, lexical or morphosyntactic structures, there are also some other constraints that affect textual genres. This means that these are the product of the history of the uses of language and that they work at a praxeologic level. These ideas apply to the…

The effect of a failure and submaximal blood flow restriction resistance exercise protocol on changes in muscle size, strength and swelling

2016

Masteroppgave i idrettsvitenskap - Universitetet i Agder 2016 Introduction: Blood flow restricted resistance exercise (BFRRE) can induce rapid increases in muscle size, strength and swelling. No previous research has investigated the importance of conducting BFRRE to voluntary failure and few studies has been carried out to investigate associations between swelling and muscle size. Therefore, the aim of the present study was twofold (1) compare changes in muscle size and strength between a failure (FA) and submaximal (SU) BFRRE protocol (2) investigate associations between swelling and muscle size. Methods: Seventeen untrained men had their legs randomized to FA and SU protocols. The interv…

Single amino acid substitutions in the glycoprotein B carboxy terminus influence the fusion from without property of herpes simplex virus type 1.

1995

Syncytial mutations of herpes simplex virus type 1 (HSV-1) strains ANG, ANG path, HFEM, tsB5 and HSZP cause extensive cell fusion and were mapped to the cytoplasmic domain of glycoprotein B (gB), within the syn 3 locus. These strains are so far the only ones which show the phenotype ‘fusion from without’ (FFWO): 60 min after infection with high m.o.i., cells in a tissue culture are fused without transcription and translation of the viral genome. In this report we detected, using the recombinants 27/III and K-7, that an amino acid exchange from Ala to Val at aa position 854 of gB is the main determinant for FFWO activity of strains ANG, ANG path and recombinant K-7. The transfer of this muta…