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showing 10 items of 2426 documents

Assessing inter- and intra-individual cognitive variability in patients at risk for cognitive impairment: the case of minimal hepatic encephalopathy

2014

Recent evidence reveals that inter- and intra-individual variability significantly affects cognitive performance in a number of neuropsychological pathologies. We applied a flexible family of statistical models to elucidate the contribution of inter- and intra-individual variables on cognitive functioning in healthy volunteers and patients at risk for hepatic encephalopathy (HE). Sixty-five volunteers (32 patients with cirrhosis and 33 healthy volunteers) were assessed by means of the Inhibitory Control Task (ICT). A Generalized Additive Model for Location, Scale and Shape (GAMLSS) was fitted for jointly modeling the mean and the intra-variability of Reaction Times (RTs) as a function of so…

AdultLiver CirrhosisMaleRiskmedicine.medical_specialtyNeurologyCirrhosisPsychometricsLiver CirrhosiModels NeurologicalIndividualityReproducibility of ResultInter-intra individual differenceNeuropsychological TestsAudiologyBiochemistryGeneralized linear mixed modelCognition DisorderCellular and Molecular NeuroscienceReaction TimemedicineHumansSub-clinical brain impairmentEffects of sleep deprivation on cognitive performanceHepatic encephalopathyAgedSubclinical infectionCirrhosiSettore M-PSI/02 - Psicobiologia E Psicologia FisiologicaNeuropsychologyReproducibility of ResultsCognitionMiddle Agedmedicine.diseaseSurgeryHepatic EncephalopathyCognitive controlNeuropsychological TestFemaleNeurology (clinical)Cognition DisordersPsychologyPsychometricPsychomotor PerformanceHuman
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Comparison of transient elastography and acoustic radiation force impulse for non-invasive staging of liver fibrosis in patients with chronic hepatit…

2011

Transient elastography (TE) is adequate for a diagnosis of cirrhosis, but its accuracy for milder stages of fibrosis is much less satisfactory. The objective of this study was to compare the performance and the discordance rate of acoustic radiation force impulse (ARFI) and TE with liver biopsy in a cohort of chronic hepatitis C (CHC) patients.One hundred thirty-nine consecutive patients with CHC were enrolled in two tertiary centers, and evaluated for histological (Metavir score) and biochemical features. All patients underwent TE and ARFI.TE was unreliable in nine patients (6.5%), while in no cases (0%) were ARFI invalid measurements recorded (P=0.029). By area under receiver operating ch…

AdultLiver CirrhosisMalemedicine.medical_specialtyHepacivirusLiver fibrosisBiopsyHepacivirusImpulse (physics)behavioral disciplines and activitiesCohort StudiesElasticity Imaging TechniquesBiopsyotorhinolaryngologic diseasesMedicineHumansProspective StudiesAcoustic radiation forceAgedHepatologybiologymedicine.diagnostic_testbusiness.industryarfi fibroscan hcv fibrosisGastroenterologyReproducibility of ResultsHepatitis CHepatitis C ChronicMiddle Agedbiology.organism_classificationmedicine.diseaseROC CurveElasticity Imaging TechniquesRNA ViralFemalesense organsRadiologyTransient elastographybusinesspsychological phenomena and processes
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RIFLE classification as predictive factor of mortality in patients with cirrhosis admitted to intensive care unit.

2009

Background and Aim: To evaluate the association of the Risk, Injury, Failure, Loss and End-stage renal failure (RIFLE) score on mortality in patients with decompensated cirrho- sis admitted to intensive care unit (ICU). Methods: A cohort of 412 patients with cirrhosis consecutively admitted to ICU was classified according to the RIFLE score. Multivariable logistic regression analysis was used to evaluate the factors associated with mortality. Liver-specific, Acute Physiology and Chronic Health Evaluation (APACHE) II, Sequential Organ Failure Assessment (SOFA) and RIFLE scores on admission, were compared by receiver-operator characteristic curves. Results: The overall mortality during ICU st…

AdultLiver CirrhosisMalemedicine.medical_specialtyTime FactorsRisk AssessmentSensitivity and SpecificitySeverity of Illness Indexlaw.inventionHepatorenal syndromelawPredictive Value of TestsRisk FactorsInternal medicineCause of DeathEpidemiologymedicineHealth Status IndicatorsHumansRifleAPACHERetrospective StudiesHepatologybusiness.industryGastroenterologyAcute kidney injuryReproducibility of ResultsOdds ratioAPACHE cirrhosis intensive care unit MELD renal failure RIFLE SOFA.Acute Kidney InjuryMiddle Agedmedicine.diseasePrognosisIntensive care unitSurgeryIntensive Care UnitsLogistic ModelsROC CurveCohortFemalebusinessKidney disease
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Working Alliance Inventory for Online Interventions-Short Form (WAI-TECH-SF): The Role of the Therapeutic Alliance between Patient and Online Program…

2020

Background: Therapeutic alliance (TA) between the patient and therapist has been related to positive therapeutic outcomes. Because Internet-based interventions are increasingly being implemented, a tool is needed to measure the TA with Internet-based self-guided programs. The Working Alliance Inventory for online interventions (WAI-TECH-SF) was adapted based on the WAI Short Form (Hatcher &amp

AdultMale020205 medical informaticsAdolescentPsychometricsonline interventionsTherapeutic AllianceHealth Toxicology and MutagenesisPsychological interventionlcsh:MedicineTherapeutic alliance02 engineering and technologytherapeutic outcomesArticle03 medical and health sciencesYoung Adult0302 clinical medicineBehavior TherapyInternal consistencySurveys and QuestionnairesCredibility0202 electrical engineering electronic engineering information engineeringHumans030212 general & internal medicineOnline interventionsDepressive symptomsAgedTherapeutic outcomesDepressionlcsh:RPublic Health Environmental and Occupational HealthReproducibility of ResultsProfessional-Patient RelationsMiddle AgedExploratory factor analysis3. Good healthAllianceTreatment OutcomeSatisfaction with the treatmentPatient Satisfactionsatisfaction with the treatmentFemalePsychologyInternet-Based InterventionClinical psychologyInternational journal of environmental research and public health
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Performance characteristics of the new Abbott Real Time MTB assay for detection of Mycobacterium tuberculosis complex in respiratory specimens

2015

The performance of the Abbott Real Time MTB assay for detection of Mycobacterium tuberculosis complex in respiratory specimens was evaluated using a standard culture as the reference. The overall concordance between both methods was 0.95. The assay displayed an excellent sensitivity (100% for smear-positive/92.3% for smear-negative specimens) and specificity (100%).

AdultMale0301 basic medicineMicrobiology (medical)AdolescentConcordance030106 microbiologyReal-Time Polymerase Chain ReactionSensitivity and SpecificityMycobacterium tuberculosisYoung Adult03 medical and health sciences0302 clinical medicineHumansMedicine030212 general & internal medicineRespiratory systemChildTuberculosis PulmonaryAgedAged 80 and overbiologybusiness.industryReproducibility of ResultsMycobacterium tuberculosisGeneral MedicineMiddle Agedbiology.organism_classificationVirologyInfectious DiseasesMycobacterium tuberculosis complexChild PreschoolFemaleReagent Kits DiagnosticbusinessDiagnostic Microbiology and Infectious Disease
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Breakdown of Thalamo-Cortical Connectivity Precedes Spike Generation in Focal Epilepsies

2017

Electroencephalography (EEG) spikes and focal epileptic seizures are generated in circumscribed cerebral networks that have been insufficiently described. For precise time and spatial domain network characterization, we applied in patients with focal epilepsy dense array 256-channel EEG recordings with causal connectivity estimation by using time-resolved partial directed coherence and 3T-magnetic resonance imaging-derived cortical and thalamus integrity reconstruction. Before spike generation, significant theta and alpha bands driven information flows alterations were noted from both temporal and frontal lobes to the thalamus and from the thalamus to the frontal lobe. Medial dorsal and ven…

AdultMale0301 basic medicineThalamusAction PotentialsElectroencephalographySensitivity and Specificity03 medical and health sciencesEpilepsy0302 clinical medicineThalamusBiological ClocksNeural PathwaysConnectomemedicineHumansIn patientFocal EpilepsiesCerebral CortexDense arraymedicine.diagnostic_testGeneral NeuroscienceReproducibility of ResultsElectroencephalographymedicine.disease030104 developmental biologyThalamo corticalFrontal lobeFemaleEpilepsies PartialNerve NetPsychologyNeuroscience030217 neurology & neurosurgeryBrain Connectivity
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Development and Psychometric Properties of the Detection of Sexual Abuse Risk Screening Scale (DSARss).

2019

People with intellectual disability (ID) are more vulnerable to being victims of sexual abuse (SA) because, in most cases, they are not able to detect the warning signs that abuse could occur. However, there is a lack of appropriate assessment tools to determine their vulnerability. To address this limitation, the current study tests the psychometric properties of the Detection of Sexual Abuse Risk Screening Scale (DSARss), a new scale developed to assess the ability of individuals with mild or moderate ID to detect the risk of SA. In all, 246 individuals with mild or moderate ID (55.3% males) completed the DSARss, along with other scales assessing related dimensions (e.g., psychopathologi…

AdultMale030506 rehabilitationPsychometricsVulnerabilitysexual abusepsychometric propertiesSeverity of Illness Index03 medical and health sciencesDisability EvaluationIntellectual DisabilitySurveys and QuestionnairesIntellectual disabilitymedicineHumans0501 psychology and cognitive sciencesGeneral PsychologyCrime Victims05 social sciencesSex Offensesrisk assessmentReproducibility of ResultsMiddle Agedmedicine.diseaseExploratory factor analysisPsychiatry and Mental healthRisk screeningSexual abuseintellectual disabilityScale (social sciences)Female0305 other medical scienceRisk assessmentPsychology050104 developmental & child psychologyClinical psychologyPsychopathologySexual abuse : a journal of research and treatment
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Validity, reliability, and sensitivity to motor impairment severity of a multi-touch app designed to assess hand mobility, coordination, and function…

2021

[EN] Background: The assessment of upper-limb motor impairments after stroke is usually performed using clinical scales and tests, which may lack accuracy and specificity and be biased. Although some instruments exist that are capable of evaluating hand functions and grasping during functional tasks, hand mobility and dexterity are generally either not specifically considered during clinical assessments or these examinations lack accuracy. This study aimed to determine the convergent validity, reliability, and sensitivity to impairment severity after a stroke of a dedicated, multi-touch app, named the Hand Assessment Test. Methods: The hand mobility, coordination, and function of 88 individ…

AdultMale030506 rehabilitationmedicine.medical_specialtyNeurologyHealth InformaticsNeurosciences. Biological psychiatry. NeuropsychiatryAssessmentFingers03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationTEORIA DE LA SEÑAL Y COMUNICACIONESMedicineHumansSensitivity (control systems)Upper-limbMulti-touch technologyStrokeReliability (statistics)Agedbusiness.industryResearchRehabilitationStroke RehabilitationMulti-touchReproducibility of ResultsINGENIERIA TELEMATICAMiddle Agedmedicine.diseaseHandMobile ApplicationsTest (assessment)StrokeStandard errorConvergent validityMotor SkillsFemale0305 other medical sciencebusinessApp030217 neurology & neurosurgeryRC321-571Journal of NeuroEngineering and Rehabilitation
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Intra and inter-raters reliability and agreement of stimulus electrodiagnostic tests with two different electrodes in sedated critically-ill patients

2019

Objective: The aim of the present study was to verify the intra- and inter-rater reliability and agreement of the stimulus electrodiagnostic test (SET) measurements obtained by pen and square elect...

AdultMale030506 rehabilitationmedicine.medical_specialtyPsychometricsElectrodiagnosisCritical IllnessPhysical Therapy Sports Therapy and RehabilitationAnesthesia GeneralStimulus (physiology)AudiologyPolyneuropathies03 medical and health sciences0302 clinical medicinemedicineHumansMuscle SkeletalElectrodesObserver Variationmedicine.diagnostic_testCritically illbusiness.industryElectrodiagnosisReproducibility of ResultsMiddle AgedElectrodiagnostic testFemale0305 other medical sciencebusiness030217 neurology & neurosurgeryPhysiotherapy Theory and Practice
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Linking Organizational Justice to Burnout: Are Men and Women Different?

2005

This study tested the links from organizational justice with burnout and the moderating role of sex in these relationships. A total of 279 contact employees (149 men and 130 women) were surveyed in 59 hotels. A questionnaire was used to measure distributive, procedural, and interactional justice as well as employees' burnout (exhaustion, cynicism, and efficacy). Hierarchical regression models, calculated to test the hypothesized effects, indicated the predominance of procedural justice over distributive and interpersonal with regard to the direct relationships between organizational justice and burnout. Analysis also showed that links from interactional justice with exhaustion and cynicism…

AdultMale05 social sciencesMultilevel modelReproducibility of Results050109 social psychologyProcedural justiceInterpersonal communicationBurnoutOrganizational CultureTest (assessment)CynicismSocial JusticeSurveys and QuestionnairesInteractional justiceOrganizational justice0502 economics and businessHumansFemale050211 marketing0501 psychology and cognitive sciencesPsychologyBurnout ProfessionalSocial psychologyGeneral PsychologyPsychological Reports
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