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showing 10 items of 2426 documents
Semi-automated retinal vessel analysis in nonmydriatic fundus photography.
2013
Purpose Funduscopic assessment of the retinal vessels may be used to assess the health status of microcirculation and as a component in the evaluation of cardiovascular risk factors. Typically, the evaluation is restricted to morphological appreciation without strict quantification. Our purpose was to develop and validate a software tool for semi-automated quantitative analysis of retinal vasculature in nonmydriatic fundus photography. Methods matlab software was used to develop a semi-automated image recognition and analysis tool for the determination of the arterial–venous (A/V) ratio in the central vessel equivalent on 45° digital fundus photographs. Validity and reproducibility of the r…
Comparison of partial coherence interferometry and ultrasound for anterior segment biometry.
2008
To assess the performance of a partial coherence interferometry (PCI)-based device for the determination of anterior segment biometry.Clinica Centrofama, Cartagena, Murcia, Spain.Central corneal thickness (CCT), anterior chamber depth (ACD), and lens thickness (LT) were measured with the ACMaster PCI anterior segment biometer and an Echoscan US-1800 ultrasound (US) biometer/pachymeter with and without cycloplegia. To determine the precision of the instruments, the same examiner took 30 consecutive CCT, ACD, and LT measurements in a single subject under the same conditions and with and without cycloplegia. The same measurements were performed in additional subjects.Twenty-one eyes (16 subjec…
The symptom check-list, SCL-90-R: its use and characteristics in chronic pain patients
2000
The SCL-90-R is a widely-used questionnaire for self-report of psychological distress and multiple aspects of psychopathology, as part of the evaluation of chronic pain patients and other non-psychiatric populations. The aim of this study is the presentation of clinical results of this multidimensional questionnaire in a convenience sample of 3540 chronic pain patients treated in a multidisciplinary pain centre. Confirmatory Factor Analysis (CFA), Exploratory Factor Analysis (EFA), single scale factor analyses and Cronbach's alphas are used to assess the internal structure and correlation to other instruments (CES-D, STAI, MPSS) to assess construct validity. It is shown that the 9 dimension…
Assessing Somatic, Psychosocial, and Spiritual Distress of Patients with Advanced Cancer
2012
Objective: For adequate distress assessment in palliative care, we developed a screening evaluation tool. Methods: Proven methods of scale construction led to a 53-item pilot form of the Advanced Cancer Patients’ Distress Scale (ACPDS). We used Hornheide Questionnaire (HQ), Palliative Outcome Scale (POS), and Minimal Documentation System (MIDOS) for validation. Advanced cancer patients (N = 168) from 3 centers for palliative medicine (aged 23-89, 51% female) filled out the questionnaire. Results: With a principal component analysis (PCA), we extracted 5 distress scales (emotional reactions/physical restrictions, communication deficits, negative social reactions, pain, and gastrointestinal s…
Translation and Testing of the Italian Version of FAMCARE-2: Measuring Family Caregivers' Satisfaction With Palliative Care.
2017
Family satisfaction is an important outcome of palliative care and is a critical measure for health care professionals to address when assessing quality of care. The FAMCARE-2 is a widely used measure of family satisfaction with the health care received by both patient and family in palliative care. In this study, a team of Italian researchers culturally adapted the FAMCARE-2 to the Italian language and psychometrically tested the instrument by measuring satisfaction of 185 family caregivers of patients admitted into two palliative care services. FAMCARE-2 showed excellent levels of internal consistency (Cronbach’s α coefficient = .96) and test–retest reliability ( r = .98, p < .01). Th…
Evaluation of two instruments of perceived symptom intensity in palliative care patients in an outpatient clinic
2015
Aims and objectives To evaluate the test–retest stability in assessments of perceived symptom intensity on the Edmonton Symptom Assessment System-revised and the European Organization for Research and Treatment of Cancer, Quality of Life Questionnaire Core 15 Palliative. The possible interchangeability between the instruments and the patients’ experiences of completing the instruments were also studied. Background The two instruments assess the same symptoms, but the symptom intensity is assessed on 11-point numerical scales on the Edmonton Symptom Assessment System-revised and on four-point verbal descriptive scales on the European Organization for Research and Treatment of Cancer, Quality…
Validation of the German Version of the Quality of Dying and Death Questionnaire for Informal Caregivers (QODD-D-Ang).
2015
Abstract Context The quality of dying and death (QOD) influences end-of-life care for patients and their relatives. To the best of our knowledge, there are currently no validated standard instruments for evaluating the QOD of patients in palliative care units (PCUs) in Germany. Objectives This study aimed to validate the German version of the multidimensional questionnaire "Quality of Dying and Death" for informal caregivers (QODD-Deutsch-Angehorige [QODD-D-Ang]) and provide a detailed report on its validity and reliability. Methods The QODD was forward/backward translated following the European Organization for Research and Treatment of Cancer guidelines. Data collected in two German palli…
Colony-Stimulating Factor-1
2015
A noninvasive means to predict the onset and recurrence of lupus nephritis (LN) before overt renal injury is needed to optimize and individualize treatment. Colony-stimulating factor-1 (CSF-1) is expressed by kidney tubules at the onset of LN, increases with disease progression, and spills into the circulation in lupus-prone mice. We tested the hypothesis that amplified expression of CSF-1 detected in the serum or urine correlates with intrarenal CSF-1 expression and histopathology (increased macrophage accumulation, activity indices) and clinical kidney disease activity and predicts the onset and recurrence of nephritis in patients with systemic lupus erythematosus (SLE). We found increase…
Development and validation of the mastocytosis quality of life questionnaire: MC-QoL
2016
Background Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients affected suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is high, there is currently no specific instrument to measure health-related quality of life (HRQoL) impairment in patients with mastocytosis. Objective The aim of this study was to develop and validate a disease-specific tool to assess HRQoL impairment in patients with cutaneous and indolent systemic mastocytosis, the Mastocytosis Quality of Life Questionnaire (MC-QoL). Methods Sixty-two potential MC-QoL items were developed in a co…
A confirmatory factor analytic validation of the Tinnitus Handicap Inventory
2015
Abstract Objective Because the postulated three-factor structure of the internationally widely used Tinnitus Handicap Inventory (THI) has not been confirmed yet by a confirmatory factor analytic approach this was the central aim of the current study. Methods From a clinical setting, N = 373 patients with chronic tinnitus completed the THI and further questionnaires assessing tinnitus-related and psychological variables. In order to analyze the psychometric properties of the THI, confirmatory factor analysis (CFA) and correlational analyses were conducted. Results CFA provided a statistically significant support for a better fit of the data to the hypothesized three-factor structure ( RMSEA…