Search results for "retreatment"

showing 10 items of 79 documents

Oxidative stress markers in the neocortex of drug-resistant epilepsy patients submitted to epilepsy surgery

2013

Summary Purpose While there is solid experimental evidence of brain oxidative stress in animal models of epilepsy, it has not been thoroughly verified in epileptic human brain. Our purpose was to determine and to compare oxidative stress markers in the neocortex of epileptic and non-epileptic humans, with the final objective of confirming oxidative stress phenomena in human epileptic brain. Methods Neocortical samples from drug-resistant epilepsy patients submitted to epilepsy surgery ( n =20) and from control, non-epileptic cortex samples ( n =11) obtained from brain bank donors without neurological disease, were studied for oxidative stress markers: levels of reactive oxygen species (ROS)…

AdultMalemedicine.medical_specialtyGlutathione reductaseNeocortexBiologymedicine.disease_causeLipid peroxidationSuperoxide dismutasechemistry.chemical_compoundEpilepsyInternal medicinemedicineHumansTreatment Failurechemistry.chemical_classificationGlutathione PeroxidaseReactive oxygen speciesEpilepsySuperoxide DismutaseGlutathione peroxidaseMiddle AgedCatalasemedicine.diseasePsychosurgeryOxidative StressGlutathione ReductaseEndocrinologyNeurologyBiochemistrychemistryCatalaseRetreatmentbiology.proteinAnticonvulsantsFemaleNeurology (clinical)BiomarkersOxidative stressEpilepsy Research
researchProduct

An 18-Month Follow-up, Randomized Comparison of Effectiveness and Safety of Two Hyaluronic Acid Fillers for Treatment of Moderate Nasolabial Folds

2016

Hyaluronic acid (HA) filler injection is a popular nonsurgical aesthetic procedure.To compare the effectiveness and safety of 2 hyaluronic acid fillers (HAEC and HARES) for treatment of moderate nasolabial folds (NLFs).This was an evaluator- and subject-blinded split-face study. HAEC or HARES was randomly assigned to the left or right NLF at baseline. Retreatment was performed after 9 months; follow-up extended to 18 months after baseline (9 months after retreatment). Effectiveness assessments included the Wrinkle Severity Rating Scale (WSRS) and subject preference. Safety assessments included adverse events (AEs) and local tolerability symptoms recorded by subjects during 3 weeks after tre…

AdultMalemedicine.medical_specialtyNasolabial FoldTime FactorsTreatment outcomeDermatology030230 surgerylaw.invention030207 dermatology & venereal diseases03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDouble-Blind MethodRandomized controlled triallawDermal FillersHyaluronic acidmedicineHumansHyaluronic AcidAgedbusiness.industryFollow up studiesPatient PreferenceGeneral MedicineMiddle AgedNasolabial foldPatient preferenceSkin AgingSurgeryTreatment Outcomemedicine.anatomical_structureMulticenter studychemistryRetreatmentFemaleSurgerybusinessFollow-Up StudiesMonth follow upDermatologic Surgery
researchProduct

Predicting Early and Sustained Virological Responses in Prior Nonresponders to Pegylated Interferon alpha-2b Plus Ribavirin Retreated With Peginterfe…

2013

GOALS: To evaluate the predictive value of complete early virological response (cEVR) on sustained virological response (SVR) following retreatment with peginterferon alpha-2a (40 kDa) plus ribavirin in previous nonresponders to peginterferon alpha-2b (12 kDa). BACKGROUND: In the randomized multinational retreatment with Pegasys in patients not responding to PegIntron therapy study, a 72-week regimen of peginterferon alpha-2a (40 kDa) plus ribavirin improved SVR rates over a standard 48-week regimen in previous nonresponders to peginterferon alpha-2b (12 kDa). cEVR, defined as hepatitis C virus RNA <50 IU/mL at treatment week 12, was an important predictor of SVR. STUDY: We conducted an exp…

AdultMalemedicine.medical_specialtyTime FactorsInterferon alpha-2Antiviral therapyAntiviral AgentsGastroenterologyPolyethylene Glycolslaw.inventionchemistry.chemical_compoundPharmacotherapyRandomized controlled trialnonresponderPredictive Value of TestslawInternal medicineRibavirinchronic hepatitis CHumansMedicinepeginterferonAdverse effectRandomized Controlled Trials as Topicbusiness.industryRibavirinGastroenterologyInterferon-alphavirus diseasesHepatitis CHepatitis C ChronicMiddle Agedmedicine.diseasepeginterferon; chronic hepatitis C; nonresponder; retreatment; sustained virological responseRecombinant Proteinsdigestive system diseasesRegimenTreatment OutcomechemistryPredictive value of testsRelative riskRetreatmentDrug Therapy CombinationFemalesustained virological responsebusinessJournal of Clinical Gastroenterology
researchProduct

TIPS for acute and chronic Budd-Chiari syndrome: a single-centre experience.

2003

Abstract Background/Aims : Transjugular intrahepatic portosystemic shunt (TIPS) is a technically challenging but feasible treatment for Budd–Chiari syndrome (BCS). However, information about the outcome, particularly in patients with liver failure, is scarce. We report our experience of TIPS for BCS. Methods : Fifteen patients with BCS underwent TIPS. Eight had hepatic failure and seven underwent TIPS for BCS uncontrolled by medical treatment. Results : Fourteen out of 15 had successful TIPS placement. Out of the eight hepatic failure patients, four died soon after TIPS: one liver rupture, one portal vein rupture, one liver failure and one pulmonary oedema. Another patient had a significant…

AdultMalemedicine.medical_specialtymedicine.medical_treatmentLiver transplantationBudd-Chiari SyndromeBalloonCatheterizationAscitesmedicineHumansAgedHepatologybusiness.industryVascular diseaseLiver failureMiddle Agedmedicine.diseaseSurgeryTreatment OutcomeChronic DiseaseRetreatmentBudd–Chiari syndromeFemaleStentsLiver functionmedicine.symptomPortasystemic Shunt Transjugular IntrahepaticbusinessTransjugular intrahepatic portosystemic shuntLiver FailureJournal of hepatology
researchProduct

Flapless application of enamel matrix derivative in periodontal retreatment: A multicentre randomized feasibility trial

2021

AIM To investigate the potential benefit of enamel matrix derivative (EMD) as adjunct to re-instrumentation of residual pockets persisting after steps 1 and 2 of periodontal therapy. MATERIAL AND METHODS 44 adult patients participated in a multicentre feasibility randomized clinical trial with split-mouth design. They had presented at re-evaluation after initial non-surgical periodontal therapy (steps 1 and 2 of periodontal therapy) for generalized periodontitis with at least 2 teeth with residual probing pocket depths (PPD) ≥5 and ≤8 mm, with bleeding on probing (BOP). Two teeth with similar PPD were randomized to receive re-instrumentation either with (test) or without (control) adjunctiv…

AdultTest groupBleeding on probingDentistryenamel matrix derivative; periodontitis; re-instrumentation; retreatment; scaling and root planingGeneralized periodontitisRoot Planinglaw.invention03 medical and health sciences0302 clinical medicineScaling and root planingRandomized controlled triallawEnamel matrix derivativemedicineHumans030212 general & internal medicineDental EnamelPeriodontitisPeriodontitisAdult patientsbusiness.industry030206 dentistrymedicine.diseaseTreatment OutcomeDental ScalingFeasibility StudiesPeriodonticsmedicine.symptombusinessJournal of Clinical Periodontology
researchProduct

Cycle scheduling for in vitro fertilization with oral contraceptive pills versus oral estradiol valerate: a randomized, controlled trial

2013

Abstract Background Both oral contraceptive pills (OCPs) and estradiol (E2) valerate have been used to schedule gonadotropin-releasing hormone (GnRH) antagonist in vitro fertilization (IVF) cycles and, consequently, laboratory activities. However, there are no studies comparing treatment outcomes directly between these two pretreatment methods. This randomized controlled trial was aimed at finding differences in ongoing pregnancy rates between GnRH antagonist IVF cycles scheduled with OCPs or E2 valerate. Methods Between January and May 2012, one hundred consecutive patients (nonobese, regularly cycling women 18–38 years with normal day 3 hormone levels and &lt;3 previous IVF/ICSI attempts)…

Adultmedicine.medical_specialtyPregnancy Ratemedia_common.quotation_subjectPopulationPhysiologyFertilization in VitroCycle schedulingReproductive technologyGonadotropin-releasing hormoneValerateContraceptives Oral Hormonallaw.inventionGonadotropin-Releasing HormoneEndocrinologyRandomized controlled trialPregnancylawInternal medicineGnRH antagonistHumansMedicineeducationMenstrual CycleMenstrual cyclemedia_commonchemistry.chemical_classificationeducation.field_of_studyEstradiolOral contraceptivesbusiness.industryResearchEstradiol valerateEstrogen pretreatmentObstetrics and GynecologyPregnancy rateEndocrinologychemistryReproductive MedicineIVFFemalebusinessmedicine.drugDevelopmental BiologyReproductive Biology and Endocrinology
researchProduct

In vitro evaluation of the ability of three apex locators to determine the working length during retreatment.

2005

The purpose of this in vitro study was to evaluate the accuracy of three apex locators in determining the working length during the retreatment process. Twenty extracted single-rooted human teeth with mature apices were used in this study. The root canal length of each tooth was measured placing a #15 file until the tip was visible at the apical foramen. The direct visual measurement was reduced by 0.5 mm and recorded. The root canals were instrumented and filled to the direct visual measurement using lateral compaction technique. After 7 days the teeth were retreated using three apex locators: ProPex, NovApex, and Root ZX, for determining the retreatment working length. Afterward, comparis…

Analysis of VarianceDental InstrumentsChi-Square Distributionbusiness.industryDentistryRoot canal lengthApex (geometry)Tooth ApexRetreatmentIn vitro studyHumansApical foramenDental Pulp CavitybusinessGeneral DentistryMathematicsJournal of endodontics
researchProduct

Midinfrared FT-IR as a Tool for Monitoring Herbaceous Biomass Composition and Its Conversion to Furfural

2015

A semiquantitative analysis by means of midinfrared FT-IR spectroscopy was tuned for the simultaneous determination of cellulose, hemicellulose, and lignin in industrial crops such as giant reed (Arundo donaxL.) and switchgrass (Panicum virgatumL.). Ternary mixtures of pure cellulose, hemicellulose, and lignin were prepared and a direct correlation area/concentration was achieved for cellulose and lignin, whereas indirect correlations were found for hemicellulose quantification. Good correspondences between the values derived from our model and those reported in the literature or obtained according to the official Van Soest method were ascertained. Average contents of 40–45% of cellulose, 2…

Article SubjectbiologySpectroscopy; Analytical Chemistry; Atomic and Molecular Physics and OpticsArundo donaxSettore ING-IND/27 - Chimica Industriale E Tecnologicabiology.organism_classificationFurfuralAtomic and Molecular Physics and OpticsAnalytical Chemistrychemistry.chemical_compoundHydrolysischemistryAtomic and Molecular PhysicsYield (chemistry)Biomass characterization FTIR lignocellulose biomass pretreatmentlcsh:QC350-467Panicum virgatumLigninOrganic chemistryHemicelluloseand OpticsCelluloselcsh:Optics. LightSpectroscopyNuclear chemistryJournal of Spectroscopy
researchProduct

Enhancing methane production from lignocellulosic biomass by combined steam-explosion pretreatment and bioaugmentation with cellulolytic bacterium

2017

Background Biogas production from lignocellulosic biomass is generally considered to be challenging due to the recalcitrant nature of this biomass. In this study, the recalcitrance of birch was reduced by applying steam-explosion (SE) pretreatment (210 °C and 10 min). Moreover, bioaugmentation with the cellulolytic bacterium Caldicellulosiruptor bescii was applied to possibly enhance the methane production from steam-exploded birch in an anaerobic digestion (AD) process under thermophilic conditions (62 °C). Results Overall, the combined SE and bioaugmentation enhanced the methane yield up to 140% compared to untreated birch, while SE alone contributed to the major share of methane enhancem…

BioaugmentationCellulolytic bacteriaResearchAnaerobic digestionCaldicellulosiruptor besciiBirchBiogasLignocelluloseSteam-explosion pretreatmentBiotechnology for biofuels
researchProduct

Molecularly Imprinted Polymers as Useful Sorbents for Bioanalysis

2022

The determination of various active compounds in different types of biological samples attracts recently considerable attention. Unfortunately, the complexity of such sample matrices requires the application of multistage analytical procedures, which by many analysts is considered the most critical step in the whole analytical process. Sample preparation techniques dedicated to bioanalysis must ensure effective isolation and enrichment of various, often trace, amounts of analytes. Furthermore, the high selectivity of extraction of the target analytes, in relation to other interfering substances co-presented in the sample, is important in this case. Therefore, over the last two decades, the …

Biologically active compoundsBioanalysisMolecularly imprinted polymers ExtractionSample pretreatment
researchProduct