Search results for "reuma"

Anti-tumour necrosis factor monoclonal antibody treatment for ocular Behçet's disease [2]

2002

Reduced exercise capacity and impaired pulmonary function in patients with scleroderma

2010

No detection of hidden HBV-DNA in patients with various rheumatic diseases treated anti-TNF agents. A two-year prospective study.

2011

European Consensus for Gynecologycal and Obstetric Management of Women with Hereditary Angioedema due to C1-Inhibitor Deficiency (HAE): PREHAEAT

2007

Anakinra drug retention rate and predictive factors of drug survival in systemic juvenile idiopathic arthritis and adult onset Still’s disease.

2019

Introduction: Only a few studies have reported the long-term efficacy of interleukin (IL)-1 inhibition in systemic juvenile idiopathic arthritis (sJIA) and adult onset Still’s disease (AOSD). We herein describe Anakinra (ANA) effectiveness expressed in terms of drug retention rate (DRR) and evaluate predictive factors of drug survival in sJIA and ASOD patients. Objectives: Examine the overall DRR of ANA in sJIA and AOSD patients. Explore the influence of biologic line of treatment, and the concomitant use of disease modifying anti-rheumatic drugs (cDMARDs) on DRR in the whole sample and stratified according to the disease thereafter; find eventual predictive factors associated with events l…

Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphoc…

2015

Invariant natural killer T cells treated with rapamycin or transforming growth factor-β acquire a regulatory function and suppress T effector lymphocytes

Cell Immunity in Inflammatory Vasculitis

2015

The vasculitides are a highly heterogeneous group of disorders characterized by the presence of inflammatory leukocytes in the vessel walls and reactive inflammation. Giant cell arteritis (GCA) and Takayasu’s arteritis (TA) are the two primary large-vessel vasculitides. Two distinct cellular pathways have been identified in GCA: Th17 polarization and IL-17 secretion and generation of Th1 cells which secrete IFN-γ. These two pathways may play different roles in the pathogenesis of vasculitides. The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are small vessel vasculitis associated with antibodies directly to myeloperoxidase (MPO-ANCA) such as eosinophilic granulo…

Increased Proportion of Comorbidities but no Deterioration of sexual QOL during a 5-year follow-up in Patients with ax-SpA in the biologic Treatment …

2021

Author's accepted manuscript. This is a pre-copyedited, author-produced version of an article accepted for publication in Rheumatology following peer review. The version of record Berg, K. H., Rohde, G., Pripp, A., Prøven, A., Benestad, E. E. P., Østensen, M. & Haugeberg, G. (2021). Increased proportion of comorbidities but no deterioration of sexual QOL during a 5-year follow-up in patients with axSpA in the biologic treatment era. Rheumatology, 60(9), 4112-4120 is available online at: https://academic.oup.com/rheumatology/article/60/9/4112/6067306 and https://doi.org/10.1093/rheumatology/keaa887. Objective. To explore patient perception of sexual quality of life (SQOL), an important categ…

Endothelial progenitor cells: Are they displaying a function in autoimmune disorders?

2016

Endothelial Progenitor Cells (EPCs) are bone marrow derived cells able to differentiate in mature endothelial cells (EC) contributing to the generation of new vessels, connecting to fibronectin, and forming colonies and/or colony forming units. Since circulating EPCs can be actively considered part of endothelial damage in several cardiovascular diseases and autoimmune disorders the possibility to have a measure for endothelium damage should be considered of interest to predict the patient out-come. At the same time the EPCs proliferative and regenerative role could be considered for therapeutic applications. Studies have been performed to elucidate the role of EPCs in Systemic Sclerosis an…

Vesículas extracelulares derivadas de células madre mesenquimales de tejido adiposo como terapia biológica en células articulares osteoartríticas

2018

La osteoartritis (OA) es la enfermedad articular más común en las personad de edad avanzada y se asocia con una pérdida progresiva de cartílago articular, sinovitis de bajo grado y varias alteraciones perjudiciales en el hueso subcondral y los tejidos periarticulares. En la OA hay un desequilibrio entre los procesos anabólicos y catabólicos de las articulaciones que se agrava por el estrés mecánico y la acumulación de mediadores inflamatorios. No existe un tratamiento eficaz para la OA, aunque se han investigado nuevas terapias, como el uso de células madre mesenquimales (MSC) o los productos que liberan en el espacio extracelular (secretoma). En esta tesis, hemos estudiado el uso potencial…