Search results for "riesgo"
showing 10 items of 348 documents
¿Influyen las diferencias culturales en los resultados de los programas de intervención con maltratadores? Un estudio con agresores españoles y latin…
2015
ResumenEn este estudio se analiza, en primer lugar, si existen diferencias entre hombres latinoamericanos inmigrantes y españoles condenados por violencia contra la mujer en las relaciones de pareja, en relación a sus actitudes hacia la violencia (i.e., gravedad percibida, culpabilización de la víctima y aceptabilidad de la violencia), atribución de responsabilidad, sexismo y riesgo de reincidencia al inicio de un programa de intervención con maltratadores. En segundo lugar, se comprueba si existen diferencias al finalizar la intervención en los resultados del programa entre inmigrantes latinoamericanos y nativos. Para ello se utiliza una muestra de 278 participantes que han finalizado un p…
Sida y prisión
2002
La relación entre droga y delincuencia hace que Instituciones Penitenciarias se con¬centren numerosas personas con antecedentes de uso de droga inyectadas (UDIs), principal práctica de riesgo para transmisión de la infección. Esta misma concentra¬ción sin embargo es una buena oportunidad de intervención terapéutica. En este trabajo se expone la situación de la infección por VlH/Sida en lnstituciones Penitenciarias(evolución y tratamiento) y los principales Programas que se aplican en la actualidad en beneficio de una prevención de la enfermedad, fundamentalmente dirigidos a la educación sexual y deshabituación del consumo de drogas, dentro del objetivo general de disminución de riesgos.
Riesgo de errores de medicación y conocimientos de farmacología del profesional de enfermería en una unidad de cuidados críticos
2017
La farmacoterapia no está exenta de riesgos para los pacientes, puede generarle una serie de daños, ya sean de naturaleza iatrogénica inherente al medicamento o como consecuencia de errores cometidos durante los procesos que componen el complejo sistema de utilización de medicamentos en los hospitales. Conocemos que los efectos adversos en España presentan una incidencia del 8,4%, siendo los más comunes los errores de medicación (37,4%). Estos datos se desprenden de grandes estudios nacionales multicéntricos, pero en cambio, no se conoce, o se estudia de manera escasa la magnitud y naturaleza de los errores de medicación que ocurren en el día a día en la práctica clínica, o si existen unida…
Predictors of short- and long-term adherence with a Mediterranean-type diet intervention: the PREDIMED randomized trial.
2016
Background: Dietary intervention success requires strong participant adherence, but very few studies have examined factors related to both short-term and long-term adherence. A better understanding of predictors of adherence is necessary to improve the design and execution of dietary intervention trials. This study was designed to identify participant characteristics at baseline and study features that predict short-term and long-term adherence with interventions promoting the Mediterranean-type diet (MedDiet) in the PREvencion con DIeta MEDiterranea (PREDIMED) randomized trial. Methods: Analyses included men and women living in Spain aged 55-80 at high risk for cardiovascular disease. Part…
CLOCK gene variation is associated with incidence of type‑2 diabetes and cardiovascular diseases in type‑2 diabetic subjects: dietary modulation in t…
2016
Background: Circadian rhythms regulate key biological processes influencing metabolic pathways. Disregulation is associated with type 2 diabetes (T2D) and cardiovascular diseases (CVD). Circadian rhythms are generated by a transcriptional autoregulatory feedback loop involving core clock genes. CLOCK (circadian locomotor output cycles protein kaput), one of those core genes, is known to regulate glucose metabolism in rodent models. Cross-sectional studies in humans have reported associations between this locus and obesity, plasma glucose, hypertension and T2D prevalence, supporting its role in cardiovascular risk. However, no longitudinal study has investigated the association between CLOCK…
Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population a…
2019
The aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndrome in the (Prevencion con Dieta Mediterranea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations ( = -0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each …
Antilymphocyte Globulin for Prevention of Chronic Graft-versus-Host Disease.
2016
Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; BACKGROUND Chronic graft-versus-host disease (GVHD) is the leading cause of later illness and death after allogeneic hematopoietic stem-cell transplantation. We hypothesized that the inclusion of antihuman T-lymphocyte immune globulin (ATG) in a myeloablative conditioning regimen for patients with acute leukemia would result in a significant reduction in chronic GVHD 2 years after allogeneic peripheral-blood stem-cell transplantation from an HLA-identical sibling. METHODS We conducted a prospective, multicenter, open-label, randomized phase 3 study of ATG as part of …
Immunocompromised patients with acute respiratory distress syndrome: Secondary analysis of the LUNG SAFE database
2018
Background: The aim of this study was to describe data on epidemiology, ventilatory management, and outcome of acute respiratory distress syndrome (ARDS) in immunocompromised patients. Methods: We performed a post hoc analysis on the cohort of immunocompromised patients enrolled in the Large Observational Study to Understand the Global Impact of Severe Acute Respiratory Failure (LUNG SAFE) study. The LUNG SAFE study was an international, prospective study including hypoxemic patients in 459 ICUs from 50 countries across 5 continents. Results: Of 2813 patients with ARDS, 584 (20.8%) were immunocompromised, 38.9% of whom had an unspecified cause. Pneumonia, nonpulmonary sepsis, and noncardiog…
Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish population.
2012
Journal Article; Research Support, Non-U.S. Gov't; SUMMARY The main objective was to evaluate the association between SNPs and haplotypes of the FABP1-4 genes and type 2 diabetes, as well as its interaction with fat intake, in one general Spanish population. The association was replicated in a second population in which HOMA index was also evaluated. METHODS 1217 unrelated individuals were selected from a population-based study [Hortega study: 605 women; mean age 54 y; 7.8% with type 2 diabetes]. The replication population included 805 subjects from Segovia, a neighboring region of Spain (446 females; mean age 52 y; 10.3% with type 2 diabetes). DM2 mellitus was defined in a similar way in b…
The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control st…
2015
Background Abdominal obesity (AO) is a common modifiable risk factor for certain non-communicable diseases associated with enhanced oxidative stress (OS). The objective of this work was to investigate whether the interaction between antioxidant vitamin intake and OS-related polymorphisms modulates gene-associated anthropometry in a Spanish population. Methods A total of 246 subjects with AO, and 492 age and gender matched non-AO subjects were included in the study. Anthropometric, biochemical, and OS parameters, and antioxidant dietary intake data were assessed using validated procedures. DNA from white blood cells was isolated and the genotype of seven polymorphisms from genes involved in …