Search results for "roche"

showing 10 items of 2666 documents

La dimension culturelle de la localisation des sites web : quelles compétences professionnelles pour sortir de l’impasse théorique ?

2018

International audience; Paris, 15-16 novembre 2018 La dimension culturelle de la localisation des sites web : quelles compétences professionnelles pour sortir de l'impasse théorique ? Le site web dans les nouveaux écosystèmes de communication multi-et interculturelle

théories de la culturecommunication interculturelletraductionapproches liquideslocalisation[SHS.INFO]Humanities and Social Sciences/Library and information sciencesformation des traducteursformationLocalisation web[SHS.LANGUE]Humanities and Social Sciences/Linguistics[SHS.LANGUE] Humanities and Social Sciences/LinguisticsComputingMilieux_MISCELLANEOUS[SHS.INFO] Humanities and Social Sciences/Library and information sciences
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Calcium mediated polyelectrolyte adsorption on like-charged surfaces.

2011

International audience; Monte Carlo simulations within the primitive model of calcium-mediated adsorption of linear and comb polyelectrolytes onto like-charged surfaces are described, focusing on the effect of calcium and polyion concentrations as well as on the ion pairing between polymers and calcium ions. We use a combination of Monte Carlo simulations and experimental data from titration and calcium binding to quantify the ion pairing. The polymer adsorption is shown to occur as a result of surface overcharging by Ca2+ and ion pairing between charged monomers and Ca2+. In agreement with experimental observations, the simulations predict that the polymer adsorption isotherm goes through …

titrationInorganic chemistrychemistry.chemical_element02 engineering and technologyCalcium010402 general chemistry01 natural sciencesIonQuantitative Biology::Cell BehaviorQuantitative Biology::Subcellular ProcessesinterfacesAdsorptionElectrochemistryGeneral Materials ScienceSpectroscopypolyelectrolytechemistry.chemical_classificationQuantitative Biology::BiomoleculesQuantitative Biology::Neurons and CognitionSurface Chemistry and ColloidsSurfaces and InterfacesPolymerPolymer adsorption021001 nanoscience & nanotechnologyCondensed Matter PhysicsPolyelectrolyte0104 chemical sciencesCondensed Matter::Soft Condensed Matter[ PHYS.PHYS.PHYS-CHEM-PH ] Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]chemistryPolyelectrolyte adsorptionChemical physicsadsorptionMonte Carlo SimulationsTitration[PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph]0210 nano-technologyLangmuir : the ACS journal of surfaces and colloids
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Voltammetric Detection of Lead(II) Using Amide-Cyclam- Functionalized Silica-Modified Carbon Paste Electrodes

2009

2-(4,8,11-Triscarbamoylmethyl-1,4,8,11-tetraazacyclotetradec-1-yl)acetamide (TETAM) derivatives bearing 1, 2, or 4 silylated arms have been synthesized and grafted to the surface of silica gel and ordered mesoporous silica samples. The resulting organic-inorganic hybrids have been incorporated into carbon paste electrodes and applied to the preconcentration electroanalysis of Pb(II). The attractive recognition properties of these cyclam derivatives functionalized with amide pendent groups toward Pb(II) species and the highly porous structure of the adsorbents can be exploited for the selective and sensitive detection of the target analyte. Various parameters affecting the preconcentration a…

titrationsynthesisDPVInorganic chemistrydetectionR4(14)aneN4extractanturea02 engineering and technology01 natural sciencesAnalytical Chemistrychemistry.chemical_compoundAdsorptionSBA15sensorAmideCyclamElectrochemistryComputingMilieux_MISCELLANEOUSsolid/liquid extractionDetection limitleadSilica gelsilica gel010401 analytical chemistryTETAM[CHIM.MATE]Chemical Sciences/Material chemistryMesoporous silica021001 nanoscience & nanotechnologygraftingamide0104 chemical sciencesCarbon paste electrodechemistry[ CHIM.MATE ] Chemical Sciences/Material chemistryKieselgel 600210 nano-technologyAcetamideElectroanalysis
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Le vignoble français face au changement climatique : l'élaboration d’une stratégie d’adaptation à partir de scénarios de prospective

2021

National audience

vignoblechangement climatiqueapproche participativeviticulture[SHS.ECO]Humanities and Social Sciences/Economics and Finance[SHS]Humanities and Social SciencesProspective[SHS.ENVIR] Humanities and Social Sciences/Environmental studies[SHS.ENVIR]Humanities and Social Sciences/Environmental studiesvin[SHS] Humanities and Social SciencesFrance[SHS.ECO] Humanities and Social Sciences/Economics and FinanceComputingMilieux_MISCELLANEOUS
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Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging

2018

International audience; Nowadays, monitoring of volatile organic compounds (VOCs) is very important in various domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant binding proteins (OBPs) as sensing materials. Three rat OBP3 derivatives with customized binding properties were designed and immobilized on the same chip for the detection of VOCs in solution by surface plasmon resonance imaging (SPRi). We demonstrated that the proteins kept their binding properties after the immobilization under optimized conditions. The obtained olfactory biosensors exhibited very low limits of detection in both concentration (200pM of beta-ionone) and in molecular weight of …

volatile organic compoundConformational change[SDV.BIO]Life Sciences [q-bio]/BiotechnologyOdorant bindingBiomedical EngineeringBiophysicsBiosensing Techniques02 engineering and technologyReceptors Odorant01 natural sciencesHexanal[SPI]Engineering Sciences [physics]chemistry.chemical_compoundElectrochemistryAnimalsVolatile organic compoundComputingMilieux_MISCELLANEOUSDetection limitchemistry.chemical_classificationVolatile Organic CompoundsChromatographyChemistry010401 analytical chemistryGeneral MedicineRepeatabilitySurface Plasmon Resonance021001 nanoscience & nanotechnologyRats0104 chemical sciencesSmellsurface plasmon resonance imagingofactory biosensor0210 nano-technologySelectivityBiosensorodorant binding proteinsBiotechnologyBiosensors and Bioelectronics
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Electrochemical sensor for phosphate ions based on laser scriber reduced graphene oxide

2022

This preliminary work shows a new and innovative way to produce laser scribed reduced graphene oxide (LSGO) electrodes using different porous substrates (ranging from paper to plastic and fabric). The obtained electrodes were also tested as electrochemical sensors towards the detection of phosphate ions in water. To obtain the electrodes, a water suspension of GO was filtered on top of substrate (such as Whatman® filter paper) and a complete sensor was obtained from its reduction using a CO2 laser. The electrode is composed of working and counter electrodes made of LSGO and a reference electrode of a Ag/AgCl obtained by using a commercial AgCl conductive paste. Phosphate ions were detected …

voltammetrySettore ING-IND/23 - Chimica Fisica ApplicataElectrochemical sensorPhosphate ionSettore ING-IND/17 - Impianti Industriali MeccaniciVoltammetryPhosphate ionspaper based elecxtrodePaper based electrodesReduced graphene oxideEectrochemical sensorreduced graphene oxide2022 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS)
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Development of an immunochromatographic assay based on carbon nanoparticles for the determination of the phytoregulator forchlorfenuron

2013

Rapid analytical methods enabling the determination of diverse targets are essential in a number of research areas, from clinical diagnostics to feed and food quality and safety. Herein, the development of a quantitative immunochromatographic assay for the detection of the synthetic phytoregulator forchlorfenuron (CPPU) is described. The competitive lateral flow immunoassay (LFIA) was based on the immobilization onto a nitrocellulose membrane of an ovalbumin-CPPU conjugate (test line) and on the use of an immunodetection ligand consisting of carbon nanoparticles labeled with an anti-CPPU monoclonal antibody through interaction with a secondary antibody. The presence of CPPU in horticultural…

water samplesCarbon nanoparticlesAnalyteImmunoreactive stripsPyridinesCarbon NanoparticlesBiomedical EngineeringBiophysicsEnzyme-Linked Immunosorbent AssayCPPUBiosensing Techniquesantibody-based immunoassayForchlorfenuronbiosensorHigh-performance liquid chromatographychemistry.chemical_compoundElectrochemistryImmunoassayDetection limitvalidationChromatographyChemistrystrip testPhenylurea Compoundslateral flow immunoassayAntibodies Monoclonalcomputer image-analysisGeneral MedicineCarbonHaptendipstick assayBBP Bioconversionrapid detectionImmunosensingNanoparticlessensitive detectionBiosensorNitrocelluloseBiotechnologyConjugate
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Le Crowdsourcing : problématisation sensible autour d'une mise en forme du lien communautaire

2014

International audience; Alors que l’utilisation des plateformes sociales (réseaux sociaux, blogs, wikis) est désormais généralisée (du côté des internautes comme des organisations), on observe un investissement et un intérêt croissant pour les plateformes de création collaborative, issues du paradigme de l’open-innovation (H.Chesbrough). On insistera plus exactement sur les dispositifs de crowdsourcing et de co-création en ligne ayant pour point commun la mise en relation de communautés (de professionnels, d’ingénieurs, de designers, d’experts, de fans…) avec les enjeux communicationnels des organisations. La recherche à propos de ces nouveaux espaces de collaboration en ligne a été jusqu’i…

web socialapproche sensible[SHS.INFO]Humanities and Social Sciences/Library and information sciences[ SHS.INFO ] Humanities and Social Sciences/Library and information sciencescrowdsourcingdesign 2.0[SHS.INFO] Humanities and Social Sciences/Library and information sciences
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L'organisation de l'université française à la lumière de ses processus de certification

1984

International audience; L'assimilation de l'école à la firme multiproduit autonomie soulève de nombreuses difficultés contextuelles. Malgré tout, l'utilisation au cas de l'établissement scolaire des outils classiques de la théorie économique de la production est susceptible de rendre compte des conséquences de ses pratiques éducatives sur un mode de fonctionnement. En faisant référence à ce cadre d'analyse, le propos de l'auteur est de révéler ici l'organisation actuelle de l'université française en examinant le rôle des divers acteurs dans le processus de production de diplômés et de vérifier, en définitive, l'existence d'un assortiment entre les établissements et leurs publics étudiants, …

Économie de l'éducationApproche économiqueCertification[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationDiplôme[ SHS.EDU ] Humanities and Social Sciences/Education[SHS.ECO]Humanities and Social Sciences/Economics and FinanceProduction de la formationThéorie économiqueEnseignement supérieurUniversitéOrganisation de l'enseignementThéorie de la production[ SHS.ECO ] Humanities and Social Sciences/Economies and financesFrance[SHS.ECO] Humanities and Social Sciences/Economics and FinanceEnseignementRôleActeur de formation
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« Product Market Regulations Impact on the Labor Market »

2020

Depuis la crise financière de 2008, les gouvernements européens ont mis en place de nombreusesréformes des régulations anticoncurrentielles des marchés des biens et services, soit desréformes des lois et règlements dans les secteurs des services et des réseaux pouvant restreindrela concurrence et les choix des entreprises. Ces réformes sont soutenues par des organismesinternationaux, comme l’OCDE et le FMI, et par une littérature abondante concluant à des effetsnégatifs de ces régulations sur l’innovation et la productivité des entreprises. Cependant, leurseffets sur le marché du travail sont assez méconnus.Ce papier étudie les effets de ces régulations sur les marchés du travail des région…

Économétrie des données de panelapproche en double-différenceOCDERégularisation[SHS] Humanities and Social Sciencesmarché du travail[SHS.ECO] Humanities and Social Sciences/Economics and FinanceEurostat
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