Search results for "roe"
showing 10 items of 9822 documents
Lexical prediction via forward models: N400 evidence from German Sign Language
2013
Models of language processing in the human brain often emphasize the prediction of upcoming input for example in order to explain the rapidity of language understanding. However,the precise mechanisms of prediction are still poorly understood. Forward models,which draw upon the language production system to setup expectations during comprehension, provide a promising approach in this regard. Here, we present an event- related potential (ERP) study on German Sign Language (DGS) which tested the hypotheses of a forward model perspective on prediction. Sign languages involve relatively long transition phases between one sign and the next, which should be anticipated as part of a forward model-…
Effects of a single session of SMR neurofeedback training on anxiety and cortisol levels.
2020
Objectives: According to some studies, a putatively calming effect of EEG neurofeedback training could be useful as a therapeutic tool in psychiatric practice. With the aim of elucidating this possibility, we tested the efficacy of a single session of ¿sensorimotor (SMR)/¿theta neurofeedback training for mood improvement in 32 healthy men, taking into account trainability, independence and interpretability of the results. Methods: A pre-post design, with the following dependent variables, was applied: (i) psychometric measures of mood with regards to anxiety, depression, and anger (Profile of Mood State, POMS, and State Trait Anxiety Inventory, STAI); (ii) biological measures (salivary leve…
Peginterferon-Α_2B plus ribavirin is more effective than peginterferon-Α_2A plus ribavirin in menopausal women with chronic hepatitis C.
2012
Under-enrolment of women to randomized clinical trials, including chronic hepatitis C, has long been recognized. The aim of this study was to identify factors predictive of sustained virological response (SVR) to PEG IFN/Ribavirin antiviral therapy in relation to gender and reproductive status of female patients involved. Seven hundred and forty-six treatment-naïve patients (431 men, 315 women) treated with Peg-IFNα-2a (180 μg/week) or Peg-IFNα-2b (1.5 μg/kg/week) plus ribavirin (800–1400 mg/day) for 24 or 48 weeks were studied between 2006 and 2010. Differences in SVR rate, overall and by gender were assessed after adjustment and propensity score matching. SVR was obtained in 44.2% of Peg-…
The modulation of causal contexts in motion processes judgment as revealed by P2 and P3
2017
The evoked response potential (ERP) procedure was used to investigate the representation of motion processes in different causal contexts, such as the collision of two squares or the repulsion of two magnets with like poles facing. Participants were required to judge whether each movement was plausible according to the causal context depicted by the cover story. Three main differences after the movement of the second object were found. First, the amplitudes at 70-170ms (N1) and 170-370ms (P2) elicited by a no-contact condition were more negative than a contact condition in the square context, whereas larger N1 and more positive amplitudes at 370-670ms were elicited by a no-contact condition…
Dental and periodontal lesions in patients with gastro-oesophageal reflux disease.
2003
Dental erosion has been considered an extraesophageal manifestation of gastro-oesophageal reflux disease, but few reports have studied the relationship between this disease and other periodontal or dental lesions. The aim of this study was to investigate the prevalence of dental and periodontal lesions in patients with gastro-oesophageal reflux disease.A total of 253 subjects were prospectively studied between April 1998 and May 2000. Two study groups were established: 181 patients with gastro-oesophageal reflux disease and 72 healthy volunteers. Clinical assessment, including body mass index and consumption of tobacco and alcohol, was performed in all subjects, as well as a dental and peri…
Earlier timbre processing of instrumental tones compared to equally complex spectrally rotated sounds as revealed by the mismatch negativity.
2014
Harmonically rich sounds have been shown to be processed more efficiently by the human brain compared to single sinusoidal tones. To control for stimulus complexity as a potentially confounding factor, tones and equally complex spectrally rotated sounds, have been used in the present study to investigate the role of the overtone series in sensory auditory processing in non-musicians. Timbre differences in instrumental tones with equal pitch elicited a MMN which was earlier compared to that elicited by the spectrally rotated sounds, indicating that harmonically rich tones are processed faster compared to non-musical sounds without an overtone series, even when pitch is not the relevant infor…
Habituation and recovery of a slow negative wave of the event-related brain potential.
2002
This study is concerned with the question of whether the late, slow negative wave 2 (SNW2) component of the event-related brain potential is a component of the orienting response (OR). As habituation of the SNW2 would be an argument for such a link with the OR, it was investigated using a variant of the classical repetition/change paradigm. Results supported major claims to be made for a component of the OR: the amplitude of the vertex SNW2 exhibited roughly the typical exponential decline with repeated stimulations (six numeric verbal stimuli presented seriatim in an ascending order) and responded incrementally to a change, at least in a narrow time slot, i.e. it exhibited partial recovery…
Regulation of the neutralizing anti-hepatitis B surface (HBs) antibody response in vitro in HBs vaccine recipients and patients with acute or chronic…
1996
Abstract Antibodies directed to the HBs antigen indicate viral clearance and the development of life-long immunity in patients that recovered from HBV infection. In HBs antigen vaccine recipients anti-HBs antibodies provide protective immunity. However, little is known about the regulation of this HBs-specific antibody response. The existence of anti-HBs-secreting B cells was demonstrated using the highly sensitive ELISPOT technique compared with conventional ELISA in serum and cell culture supernatants. In the peripheral blood of patients with acute self-limited hepatitis B, HBs-specific B cells were demonstrated with a high frequency despite undetectable anti-HBs serum antibodies. HBV-imm…
Automatic and controlled processing of acoustic and phonetic contrasts
2003
Changes in the temporal properties of the speech signal provide important cues for phoneme identification. An impairment or inability to detect such changes may adversely affect one's ability to understand spoken speech. The difference in meaning between the Finnish words tuli (fire) and tuuli (wind), for example, lies in the difference between the duration of the vowel /u/. Detecting changes in the temporal properties of the speech signal, therefore, is critical for distinguishing between phonemes and identifying words. In the current study, we tested whether detection of changes in speech sounds, in native Finnish speakers, would vary as a function of the position within the word that the…
The development of involuntary and voluntary attention from childhood to adulthood: A combined behavioral and event-related potential study
2006
Abstract Objective This study investigated auditory involuntary and voluntary attention in children aged 6–8, 10–12 and young adults. The strength of distracting stimuli (20% and 5% pitch changes) and the amount of allocation of attention were varied. Methods In an auditory distraction paradigm event-related potentials (ERPs) and behavioral data were measured from subjects either performing a sound duration discrimination task or watching a silent video. Results Pitch changed sounds caused prolonged reaction times and decreased hit rates in all age groups. Larger distractors (20%) caused stronger distraction in children, but not in adults. The amplitudes of mismatch negativity (MMN), P3a, a…