Search results for "roe"
showing 10 items of 9822 documents
Liver disease severity and low bone mineral density in HIV mono-infected and HIV/HCV co-infected patients
2014
Background: In this study we assess: prevalence of osteopenia, osteoporosis and reduced bone mineral density in HIV infection and HIV / HCV co-infection;risk factors associated with reduced bone mineral density(BMD); relationship between bone mineral density and reduced liver fibrosis (FE) measured as "liver stiffness" (LS), by FibroScan ® in patients co-infected with HIV / HCV; relationship between reduced bone mineral density and cardiovascular risk assessed with the 10-year Framingham risk score (FRS) in HIV / HCV co-infected Patients And Methods: One hundred and ninety-four HIV-infected subjects (121 males =62% and 73 females = 38 %): 129 HIV-infected ( 66.5 % ) and 65 HIV / HCV co-infe…
Clinical Significance of Tie-2-Expressing Monocytes/Macrophages and Angiopoietins in the Progression of Ovarian Cancer—State-of-the-Art
2022
Tumour growth and metastasis are specific to advanced stages of epithelial ovarian cancer (EOC). Tumour angiogenesis is an essential part of these processes. It is responsible for providing tumours with nutrients, metabolites, and cytokines and facilitates tumour and immune cell relocation. Destabilised vasculature, a distinctive feature of tumours, is also responsible for compromising drug delivery into the bulk. Angiogenesis is a complex process that largely depends on how the tumour microenvironment (TME) is composed and how a specific organ is formed. There are contrary reports on whether Tie-2-expressing monocytes/macrophages (TEMs) reported as the proangiogenic population of monocytes…
Statistical analyses on the essential oil of italian coriander (coriandrum sativum L.) fruits of different ages and origins
2002
Thirty-one samples of Coriandrum sativum L. fruits, of different origin, year of cultivation (harvest) and crop management systems were subjected to volatile component analysis by combining Head Space Solid Phase Microextraction (HS-SPME) with GC/MS. In order to determine the importance of the major sources of volatile variability, some statistical analyses, including Cluster Analysis (CA) and Principal Component Analysis (PCA), were performed on the obtained data. The compounds, which gave the main contribution to the partition and classification of the original data, were α-pinene, p-cymene, γ-terpinene and linalool. The age of the fruits, which ranged from 1–16 years, seemed to generate …
UV filters: From sunscreens to human body and the environment
2007
Recognition of the harmful effects of ultraviolet (UV) radiation on the skin has triggered development of organic chemicals (commonly referred as UV filters) that can absorb UV radiation and attenuate the negative effects of sunlight exposure. Depending on the properties and the intended degree of protection, a wide array of combinations is being marketed as delivering protection against most kinds of UV-induced skin damage. However, some UV filters have dermatological implications, so maximum applicable concentrations have been established. To monitor to what extent commercial products comply with the mandatory limits, several analytical methods have been used for their determination in co…
Genetic profile and immunohistochemical study of clear cell renal carcinoma: Pathological-anatomical correlation and prognosis.
2021
Abstract Introduction Renal cell carcinoma (RCC) accounts for 2–3% of all tumors being the most frequent solid lesion in the kidney. Objective To determine what genetic alterations and immunohistochemical (IHC) of clear cell renal carcinoma (ccRCC) are associated with prognosis and tumor aggressiveness. Patients and Methods Experimental analytical study with 57 patients who underwent radical and partial nephrectomy between 2005 and 2011, all with diagnosis of ccRCC and minimum post-operative follow-up of 36 months. The pathological study included IHC determination of biomarkers associated (CAIX, CAM 5.2, CD10, c-erbB-2, EGFR, HIF-1a, Ki67, MDM2, PAX-2 y 8, p53, survivin and VEGFR 1 and 2). …
Expression of p63, p53 and ki-67 in patients with cervical intraepithelial neoplasia
2017
Objective: Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries a risk of progression to cervical cancer. The aim of this study was to compare expression of three biomarkers named p53, p63 and Ki-67 in patients with various grades of cervical intraepithelial neoplasia and in a control group. Material and Method: 58 patients were enrolled in the study. Each patient underwent a colposcopy-guided biopsy of the cervix. Immunostaining for markers (p53, p63 and Ki-67) was performed on tissue samples of normal cases (n=10), CIN I (n=20), CIN II (n=14), and CIN III (n=14). Results: Our study showed a significant increase of the expression of t…
Ķīmiskā sastāva izvērtējums koksnes pelnos
2021
Ķīmiskā sastāva izvērtējums koksnes pelnos. Neimane M., zinātniskā darba vadītājs Pētnieks Mg.chem. Vitālijs Lazarenko. Bakalaura darbs, 33 lpp., 7 attēli, 16 tabulas, 42 literatūras avoti, 7 pielikumi. Latviešu valodā. Darbā tika analizēts makro- un mikro-, un retzemju elementu saturs smagajos un vieglajos koksnes pelnos. Paraugi tika ievākti no dažādām katlu mājām Latvijas teritorijā. Koksnes pelnu paraugiem tika veikts izvilkums koncentrētā slāpekļskābē. Iegūtajos šķīdumos ķīmisko elementu kvantitatīvais saturs tika noteikts ar ICP-MS analīzes metodi. Tika noteikts arī koksnes pelnu pH un elektrovadītspēja. Iegūtie rezultāti tika apstrādāti, izvērtēti un salīdzināti ar literatūras datiem…
Vecāku līdzestība Gastroezofageālā refluksa slimības pacientu aprūpē
2020
Bakalaura darba tēma – Vecāku līdzestība Gastroezofageālā refluksa slimības pacientu aprūpē. Tēmas aktualitāti nosaka, ka gastroezofageālās refluksa slimība ir izplatīta visās bērnu vecuma grupās, un vecāku līdzestība ir svarīgs priekšnoteikums pacientu dzīves kvalitātes uz-labošanai. Darba mērķis ir noskaidrot vecāku līdzestību gastroezofageālā refluksa slimības pacientu aprūpē. Pētījuma hipotēze – Vecāki ir līdzestīgi Gastroezofageāla refluksa slimības pacientu ap-rūpē. Pētniecības metode – kvantitatīvs Pētniecības instruments – aptaujas anketa Secinājumi – Pareizi veicot pacientu piederīgo izglītošanu iespējams panākt labus rezul-tātus vecāku līdzestībā. Līdzestība veicina pacienta dzīve…
Methylprednisolone-induced hepatotoxicity in a 16-year-old girl with multiple sclerosis.
2018
Multiple sclerosis (MS) is a chronic inflammatory disease with demyelination of the central nervous system. High-dosage corticosteroids are the first-line therapy in the acute relapsing of MS. We report a case of severe high-dose methylprednisolone-induced acute hepatitis in a patient with a new diagnosis of MS. A 16-year-old girl was admitted for urticaria, angioedema, nausea and vomiting a month later she had been diagnosed with MS and treated with high-dosage methylprednisolone. Laboratory investigations showed hepatic insufficiency with grossly elevated liver enzymes. A liver biopsy showed focal centrilobular hepatocyte necrosis with interface hepatitis. Methylprednisolone-induced hepat…
Redox signaling in acute pancreatitis: roles of PGC-1α and sulfiredoxin
2020
La pancreatitis aguda es un proceso inflamatorio agudo de la glándula pancreática que conduce frecuentemente a complicaciones locales y sistémicas. En la actualidad, es la principal causa de admisión hospitalaria por enfermedad gastrointestinal y su incidencia ha aumentado considerablemente durante la última década.Entre los mecanismos fisiopatológicos más relevantes en las primeras fases de la pancreatitis aguda se encuentran: la activación intracelular de proteasas, la alteración en la secreción de las células acinares, la activación de la respuesta inflamatoria y la muerte celular. Con frecuencia, estos mecanismos actúan sinérgicamente durante el inicio y la progresión de la pancreatitis…