Search results for "rpb"
showing 4 items of 4 documents
Metabolic Inflammation-Associated IL-17A Causes Non-alcoholic Steatohepatitis and Hepatocellular Carcinoma
2016
Obesity increases hepatocellular carcinoma (HCC) risks via unknown mediators. We report that hepatic unconventional prefoldin RPB5 interactor (URI) couples nutrient surpluses to inflammation and non-alcoholic steatohepatitis (NASH), a common cause of HCC. URI-induced DNA damage in hepatocytes triggers inflammation via T helper 17 (Th17) lymphocytes and interleukin 17A (IL-17A). This induces white adipose tissue neutrophil infiltration mediating insulin resistance (IR) and fatty acid release, stored in liver as triglycerides, causing NASH. NASH and subsequently HCC are prevented by pharmacological suppression of Th17 cell differentiation, IL-17A blocking antibodies, and genetic ablation of t…
Changements à court terme de la composition des communautés de champignons mycorhiziens à arbuscules et des populations de Rhizophagus irregularis en…
2014
La mycorhize à arbuscule a un important potentiel d’amélioration de la nutrition minérale des plantes, fort utile dans le contexte agricole. Cependant, certaines pratiques culturales sont connues pour avoir un effet néfaste sur la diversité des champignons mycorhiziens à arbuscules (Glomeromycètes). Il est donc nécessaire de mieux comprendre les dynamiques de leurs communautés et populations pour pouvoir préserver et gérer le potentiel symbiotique. Dans cette étude, nous avons étudié les effets séparés et conjoints du retournement du sol et des fertilisations phosphatée et azotée du sol sur la structure des communautés des Glomeromycètes et sur les populations de l’espèce Rhizophagus irregu…
Persistence and effectiveness of Rhizophagus irregularis isolate IR27 on the fruit production of jujube trees in a semi-arid field condition
2017
International audience
RPB1 as a marker gene to analyze communities of arbuscular mycorrhizal fungi (Glomeromycota)
2014
The influence of agricultural practice on the diversity of Arbuscular mycorrhizal fungi (AMF, Glomeromycota) continues to be an important research question as these mutualistic symbionts are known to improve plant growth and soil quality. To this day, studies of community diversity in AMF have exclusively been based on nuclear ribosomal gene regions, such as the small and large subunits and the ITS region. In the Glomeromycota, these regions show high intra-organism polymorphism, which can seriously complicate interpretation of diversity data. We chose the rpb1 gene as an alternative marker as this putative single-copy gene has been shown to be monomorphic within fungal isolates but shows a…