Search results for "script"
showing 10 items of 5143 documents
Set Descriptors for Visual Evaluation of Human Corneal Endothelia
2001
Images of corneal endothelium obtained from specular microscopy are of great importance in the evaluation of the corneal endothelium status. Several commercial tools provide some numerical descriptors to characterize these images in terms of cell density, hexagonality, and some descriptive statistics of the cell areas. However, it is a too simple analysis that only detects severe abnormal endothelia with many irregular and large cells. Detection of subtle abnormalities needs a more refined analysis. This paper proposes a shape-size descriptor based on some modified versions of the geometric covariogram. This descriptor is presented as a valid alternative to the classical analysis that provi…
Impacts of COVID-19 and pandemic control measures on public transport ridership in European urban areas – The cases of Vienna, Innsbruck, Oslo, and A…
2021
The study uses the case of two regions with small and medium sized cities (Agder in Norway and the greater Innsbruck area in Austria) and two European capitals, Vienna and Oslo, to showcase the impact of the COVID-19 pandemic on public transport ridership in northern and central Europe. The comprehensive timeline of actions taken by governments and public transport providers in Austria and Norway, and their impact on public transport ridership in the first and second waves of the pandemic form the basis of a descriptive study. Comparing the data, a strong negative impact on the public transport patronage in the first wave of the pandemic was found, despite a comparable low number of cases p…
Platinum chloride-based viability RT-qPCR for SARS-CoV-2 detection in complex samples.
2021
Isolation, contact tracing and restrictions on social movement are being globally implemented to prevent and control onward spread of SARS-CoV-2, even though the infection risk modelled on RNA detection by RT-qPCR remains biased as viral shedding and infectivity are not discerned. Thus, we aimed to develop a rapid viability RT-qPCR procedure to infer SARS-CoV-2 infectivity in clinical specimens and environmental samples. We screened monoazide dyes and platinum compounds as viability molecular markers on five SARS-CoV-2 RNA targets. A platinum chloride-based viability RT-qPCR was then optimized using genomic RNA, and inactivated SARS-CoV-2 particles inoculated in buffer, stool, and urine. Ou…
Multivariate analysis in the identification of biological targets for designed molecular structures: The BIOTA protocol
2013
In this work the new protocol BIOlogical Target Assignation (BIOTA) for the prediction of the biological target from molecular structures is proposed. BIOTA is based on the Principal Components Analysis (PCA) application on a matrix of ligands versus molecular descriptors. The application of BIOTA could allow to hypothesize the mechanism of action of a candidate drug prior to its biological evaluation or to repurpose old drugs. The protocol can be fine-tuned by choosing opportune targets (biological or not) and molecular descriptors, and it can be useful in every fields in with it is possible to collect set of compounds with known properties. The robustness of the protocol depends from diff…
Multicomponent Exercise Training Combined with Nutritional Counselling Improves Physical Function, Biochemical and Anthropometric Profiles in Obese C…
2020
Aerobics or strength exercise plus diet interventions have been shown to counteract childhood obesity. However, little is known with regard to periodized multicomponent exercise interventions combined with nutritional counselling, which might be less demanding but more enjoyable and respectful of children and adolescents&rsquo
The barrier height of the F+H2 reaction revisited: coupled-cluster and multireference configuration-interaction benchmark calculations.
2008
Large scale coupled-cluster benchmark calculations have been carried out to determine the barrier height of the F+H2 reaction as accurately as possible. The best estimates for the barrier height of the linear and bent transition states amount to 2.16 and 1.63 kcal/mol, respectively. These values include corrections for core correlation, scalar-relativistic effects, spin-orbit effects, as well as the diagonal Born-Oppenheimer correction. The CCSD(T) basis-set limits are estimated using extrapolation techniques with augmented quintuple and sextuple-zeta basis sets, and remaining N-electron errors are determined using coupled-cluster singles, doubles, triples, quadruples calculations with up t…
Il provvedimento di assegnazione della casa familiare su un immobile ipotecato: quando le ragioni creditorie prevalgono su quelle della famiglia
2018
L'articolo, partendo dall'analisi di una sentenza del Tribunale di Bari, si occupa del provvedimento di assegnazione della casa familiare e della relativa opponibilità al creditore ipotecario che abbia acquistato il suo diritto in base ad atto iscritto anteriormente alla emissione o trascrizione del provvedimento stesso The article, starting from the analysis of a sentence of the Court of Bari, deals with the provision of assignment of the family home and its enforceability to the mortgage lender who has acquired his right on the basis of an act written before the issuance or transcription of the provision same
Influence du court noué sur la diversité fonctionnelle des champignons mycorhiziens à arbuscules dans des racines et du sol de vigne
2022
Le court-noué (CN) correspond à un dépérissement infectieux (népovirus) qui apparaît par taches au sein des parcelles. Cette maladie entraîne une dégénérescence progressive de la vigne qui conduit in fine à la mort des ceps. A l’heure actuelle, environ 60% du vignoble national serait touché, dont 30% de façon importante. Seize népovirus sont responsables de dégénérescence ou de dépérissement de la vigne. Cependant, le Grapevine FanLeaf Virus (GFLV) est le principal agent responsable. Il est transmis spécifiquement de plante à plante par un nématode ectoparasite du sol, Xiphinema index. Les nématodes, en piquant successivement deux ceps voisins dont les racines sont proches, inoculent le vir…
Proteomic analysis highlights the role of detoxification pathways in increased tolerance to Huanglongbing disease.
2016
Background Huanglongbing (HLB) disease is still the greatest threat to citriculture worldwide. Although there is not any resistance source in the Citrus germplasm, a certain level of moderated tolerance is present. A large-scale analysis of proteomic responses of Citrus may help: 1) clarifying physiological and molecular effects of disease progression, 2) validating previous data at transcriptomic level, and 3) identifying biomarkers for development of early diagnostics, short-term therapeutics and long-term genetic resistance. Results In this work we have conducted a proteomic analysis of mature leaves of two Citrus genotypes with well-known differing tolerances to HLB: Navel orange (highl…
Potential predictability of crop impacting climate variables for East Africa and application to sorghum in the Mt Kenya area
2013
In Southern countries with rural low income populations, the vulnerability of rainfed agriculture to rainfall variability requires effective solutions to mitigate the effects of climatic hazards on crops. Predicting the characteristics of rainy seasons some time before they start should help the establishment of agricultural adaptation strategies to rainfall hazards. This is the objective of the present study, focused on East Africa (Kenya and northern Tanzania), and divided in three parts:- Define and document intra-seasonal descriptors (ISD) that will be considered in the predictability study. A new methodological approach has been developed in order to define the onset date (ORS) and the…