Search results for "script"
showing 10 items of 5143 documents
Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome
1998
The LIM-homeodomain protein Lmxlb plays a central role in dorso-ventral patterning of the vertebrate limb1. Targeted disruption of Lmxlb results in skeletal defects including hypoplas-tic nails, absent patellae and a unique form of renal dysplasia (see accompanying manuscript by H. Chen et al.; ref. 2). These features are reminiscent of the dominantly inherited skeletal malformation nail patella syndrome (NFS). We show that LMX1B maps to the NFS locus and that three independent NFS patients carry de novo heterozygous mutations in this gene. Functional studies show that one of these mutations disrupts sequence-specific DNA binding, while the other two mutations result in premature terminatio…
Lucretius Franco-Hibernicus: Dicuil’s Liber de Astronomia and the Carolingian Reception of De Rerum Natura
2020
Abstract Since its coinage in the nineteenth century, the concept of Carolingian renaissance has been primarily based on the revival of classical texts promoted by Charlemagne and his successors. Among the positive consequences of Carolingian classicism is the careful—if discreet—preservation of the text of Lucretius’s De Rerum Natura, which survives in three valuable ninth-century manuscripts. Whereas rigorous philological studies of these manuscripts have been offered, little attention has been paid to their role in, and connection with, the reception of Lucretius in ninth-century literature. It has been generally assumed that for the Carolingians the DRN was essentially a source for gram…
Advanced Stochastic Petri Net Modeling with the Mercury Scripting Language
2017
Formal models are widely used in performance and dependability studies of computational systems. Graphical modeling tools allow users to compose such models with ease, but they complicate the creation of models with a dynamic/complex structure, the hierarchical arrangement of different models, and the automatic execution of models with different parameter configurations. To overcome this problem, we created a scripting language for the Mercury tool that supports the combination of different modeling approaches (e.g., Stochastic Petri Nets and Reliability Block Diagrams) in a single project. In this paper, we focus on the extensions developed to improve the capabilities of Generalized Stocha…
Effective interactions in Ricci-Based Gravity below the non-metricity scale
2020
We show how minimally-coupled matter fields of arbitrary spin, when coupled to Ricci-Based Gravity theories, develop non-trivial effective interactions that can be treated perturbatively only below a characteristic high-energy scale $\Lambda_Q$. Our results generalize to arbitrary matter fields those recently obtained for spin 1/2 fields in \cite{Latorre:2017uve}. We then use this interactions to set bounds on the high-energy scale $\Lambda_Q$ that controls departures of Ricci-Based Gravity theories from General Relativity. Particularly, for Eddington-inspired Born-Infeld gravity we obtain the strong bound $ |\kappa|<3.5 \times 10^{-14} \text{ m}^5 \text{kg}^{-1}\text{s}^{-2} $.
Acceleration radiation, transition probabilities, and trans-Planckian physics
2010
An important question in the derivation of the acceleration radiation, which also arises in Hawking's derivation of black hole radiance, is the need to invoke trans-Planckian physics in describing the creation of quanta. We point out that this issue can be further clarified by reconsidering the analysis in terms of particle detectors, transition probabilities and local two-point functions. By writing down separate expressions for the spontaneous-and induced-transition probabilities of a uniformly accelerated detector, we show that the bulk of the effect comes from the natural (non-trans-Planckian) scale of the problem, which largely diminishes the importance of the trans-Planckian sector. T…
What do dental college clinicians know about oral cancer and its risk factors?: An assessment among final year students, interns and faculty members …
2018
Background: The ability of health care professionals to perform oral cancer examination depends partly on their knowledge of the disease and its risk factors. This study aimed to assess and compare the knowledge of final year students, interns and faculty members regarding oral cancer and its risk factors.Material and Methods: A 35-item questionnaire about knowledge of oral cancer and its risk factors was distributed among participants from Jazan University's Dental School. A minimum score of 18 was the cut-off point for an acceptable total score of oral cancer knowledge [OCTS]. Descriptive statistics described the relations between demographics variables and knowledge levels of participant…
’-omics’ technology and human reproduction: reproductomics
2012
The success of assisted reproduction technology is highly dependent on a precise selection of gametes and embryos and determining the best endometrial window for embryo implantation. For many years, morphological criteria have constituted the only way to assess spermatozoon, oocytes, embryos and endometrial samples in order to improve outcomes. However, this approach has reached a ceiling of success and has been related to unacceptably high rates of multiple pregnancies. New technologies have been developed in order to improve the results and reduce risks via better selection of those gametes and embryos with the highest pregnancy potential, and of more favorable endometrial environments fo…
Importance of Webpage Content and Design for Higher Education Export
2021
Higher education export is gaining more and more importance taking into account international competition, the benefits offered by the industry and demographic changes in many countries – the number of local students is reducing due to low birth rates and extensive emigration of young people. There are many academic publications on several aspects related to higher education export. The aim of research is to analyse foreign students’ evaluation on the importance of different organisations’ (universities, agencies dealing with higher education export, ministries) webpage content and design for higher education export. Research methods used: scientific literature review analysis, evaluation o…
Scripted Collaboration and Group‐Based Variations in a Higher Education CSCL Context
2009
Scripting student activities is one way to make Computer‐Supported Collaborative Learning more efficient. This case study examines how scripting guided student group activities and also how different groups interpreted the script; what kinds of roles students adopted and what kinds of differences there were between the groups in terms of their activities. Seven small groups of higher education students participated in the study. According to the findings, scripting enhanced collaboration and ensured that all groups were able to complete the task, but despite the script the groups' activities varied during the task and the script could not guarantee any “high‐level” participation by all stud…
Epistemic cooperation scripts in online learning environments: Fostering learning by reducing uncertainty in discourse?
2005
Using online learning environments in higher education offers innovative possibilities to support collaborative learning. However, online learning creates new kinds of problems for participants who have not previously worked with each other. One of these problems is uncertainty which occurs when participants do not know each other. According to the uncertainty reduction theory, low uncertainty level increases the amount of discourse and decreases the amount of information seeking. Therefore, uncertainty may influence online discourse and learning. This study investigates the effects of an epistemic cooperation script with respect to the amount of discourse, information seeking and learning …