Search results for "script"

showing 10 items of 5143 documents

Regulation of T cells in asthma: implications for genetic manipulation

2004

PURPOSE OF THE REVIEW Allergic asthma is a disease characterized by airway hyperresponsiveness, inflammation and remodeling. In the past few decades it has become clear that the pathogenesis and development of this disease is controlled by cytokines released by CD4 T helper type 2 lymphocytes that develop under the influence of natural killer lymphocytes. At birth, T cell priming exhibits a T helper type 2 bias and the development of the T helper phenotype is determined in the first year of life by environmental exposure to virus or bacterial substances or environmental allergens in genetically predisposed individuals. Decreased exposure to infection in early childhood has thus been linked …

LipopolysaccharidesT-LymphocytesT cellImmunologyPriming (immunology)Receptors Cell SurfaceInflammationBiologyType 2 immune responseImmune systemAntigenHygiene hypothesismedicineHumansImmunology and AllergyGeneticsMembrane GlycoproteinsToll-Like ReceptorsT-Lymphocytes Helper-InducerEnvironmental exposureAsthmamedicine.anatomical_structureImmunologyCytokinesmedicine.symptomT-Box Domain ProteinsTranscription FactorsCurrent Opinion in Allergy and Clinical Immunology
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Effect of indomethacin on the kinetics of tumour necrosis factor alpha release and tumour necrosis factor alpha gene expression by human blood monocy…

1991

Summary In this investigation we have examined the effects of indomethacin, an inhibitor of the cyclooxygenase pathway of arachidonic acid, upon the kinetics of the release of tumour necrosis factor alpha (TNF) and of the expression of TNF gene by lipopolysaccharide (LPS)-stimulated human blood monocytes (BM). Following stimulation of BM with LPS, TNF was released within 2 h, reached peak values at 8 h and declined at subsequent time-points (24 and 48 h). Indomethacin (10−5 m ) slightly stimulated the production of TNF at 2, 4, and 8 h and prevented the decline of TNF observed at 24 and 48 h. This effect was related to the persistence of TNF synthesis, as demonstrated by kinetics evaluation…

LipopolysaccharidesTranscription GeneticLipopolysaccharideNeutrophilsmedicine.medical_treatmentIndomethacinProstaglandinIn Vitro TechniquesPharmacologyDinoprostoneCyclooxygenase pathwaychemistry.chemical_compoundGene expressionmedicineHumansRNA MessengerPharmacologyTumor Necrosis Factor-alphabusiness.industryMonocyteKineticsmedicine.anatomical_structureCytokineGene Expression RegulationchemistryImmunologyIndicators and ReagentsArachidonic acidTumor necrosis factor alphabusinessPharmacological Research
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Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promot…

1997

Interleukin-12 (IL-12) is a proinflammatory cytokine produced by antigen-presenting cells in response to many microbial infections. IL-12 plays an important role in the generation of T helper type-1 cells, which favor cell-mediated immune response. IL-12 is composed of two different subunits, p40 and p35, whose expression can be regulated concomitantly or differentially. Monocytic cells, the major producers of IL-12, can be primed by interferon-gamma (IFN-gamma) to produce optimal amounts of IL-12 in response to LPS stimulation as a consequence of bacterial infection. The priming effect is exerted primarily at the transcriptional level on the p40 promoter in conjunction with the effects of …

LipopolysaccharidesTranscription GeneticSequence HomologyStimulationbiosynthesis/geneticsBiochemistryChromatography Affinitychemistry.chemical_compoundMiceAnimals Base Sequence Cell Line Cell Nucleus; metabolism Chromatography; Affinity DNA-Binding Proteins Humans Interferon-gamma; pharmacology Interleukin-12; biosynthesis/genetics Kinetics Lipopolysaccharides; pharmacology Mice Molecular Sequence Data Nuclear Proteins; isolation /&/ purification/metabolism Promoter Regions; Genetic Protein-Tyrosine Kinases; metabolism Proto-Oncogene Protein c-ets-2 Proto-Oncogene Proteins; isolation /&/ purification/metabolism Repressor Proteins Sequence Homology; Nucleic Acid Trans-Activators; isolation /&/ purification/metabolism Transcription Factors Transcription; Genetic; drug effectsPromoter Regions GeneticChromatographyNuclear ProteinsMethylationProtein-Tyrosine KinasesInterleukin-12DNA-Binding ProteinsTranscriptionMolecular Sequence DataBiologyProinflammatory cytokineCell LineProto-Oncogene Protein c-ets-2Promoter RegionsInterferon-gammaGeneticSequence Homology Nucleic AcidProto-Oncogene ProteinsAnimalsHumansMolecular BiologyTranscription factorCell NucleusMolecular massBase SequenceNucleic Acidisolation /&/ purification/metabolismPromoterCell BiologyMolecular biologyIn vitroRepressor ProteinsKineticschemistryAffinitydrug effectsTrans-ActivatorspharmacologymetabolismDNATranscription Factors
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Défaut d'inscription sur la liste de l'article R. 622-15. Perte du privilège du paiement prioritaire. Conservation du droit de poursuite du créancier

2017

International audience; (Com. 28 juin 2016, n° 14-21.668, arrêt n° 632 FS-P+B, Sté Innelec multimedia c/ Sté Villa Francis, ès qual., D. 2016. 1494, et les obs. ; Rev. sociétés 2016. 550, obs. L. C. Henry ; RJDA 10/2016, n° 709)

Liquidation judiciaire[SHS.DROIT]Humanities and Social Sciences/Law[SHS.DROIT] Humanities and Social Sciences/LawREDRESSEMENT ET LIQUIDATION JUDICIAIRESListe des créancesDéfautInscription
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Les listes dans le discours visuel du Moyen Âge italien. Le cas de Rome aux XIe et XIIe siècles

2019

ListMedieval inscriptions[SHS.ARCHEO] Humanities and Social Sciences/Archaeology and PrehistoryIconographyHistory of writingGoodySettore L-ART/01 - Storia dell'Arte MedievaleEpigraphy; History of writing; List; Goody; Medieval inscriptions; IconographyEpigraphy
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[Miscellanea patristica]

Ms Títol proporcionat pel catalogador Col·lació: Pergamí, f. i (pergamí actual) + ii (paper) + 201+ i (pergamí actual) ; reclams cada deu folis ; foliació original en números àrabs i moderna a llapis Composició: Escrit a dues columnes a 44 línies (f. 1r) Escriptura: Gòtica textual cal·ligràfica. Anotacions marginals d'època posterior Decoració: Caplletres decorades amb tinta de color blau i vermell. Alguns titolets en vermell Enquadernació: Restaurada. Plateresca, pell verda sobre fusta amb ferros freds i l'escut del Duc de Calàbria amb ferros daurats. Capçada amb fils de color vermell i verd. Talls acolorits en vermell. Títol daurat al llom: "Augus[tinus] de octo q[uestionibus]" Origen: Co…

Literatura cristiana primitiva Escriptors llatinsLiteratura cristiana primitiva Escriptors grecsPares de l'Església
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Runology and historical sociolinguistics: On runic writing and its social history in the first millennium

2015

AbstractThis paper argues that the rise and the transmission of the runes is largely determined by sociolinguistic factors. First, the olderfuþarkis identified as a unique Germanic design, adapted from Latin or Greek sources by one or more well-born Germani to mark group identity and status. Hence it is rather unlikely that the search for an exact source alphabet of the olderfuþarkwill make a major breakthrough in future research. Second, the present author argues that the extension of thefuþarkin the Anglo-Frisian setting is due to high-scale contact with the Christian Church, including Latin manuscript culture and Classical grammatical schooling, whereas these factors were almost entirely…

LiteratureChristian ChurchLinguistics and LanguageHistoryManuscript culturebusiness.industryLanguage and LinguisticsExtension (metaphysics)Collective identityRunesSocial historyAlphabetbusinessSociolinguisticsJournal of Historical Sociolinguistics
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THE KNOT SCRIPT – THE LOST WRITING SYSTEM OF THE LATVIAN LANGUAGE

2016

The article analyses a writing system of the Latvian language that has been scarcely researched before. The evidence of the usage of the knot script and song clews is present in the Latvian folklore, although it has been commonly considered as a metaphor. At the beginning of the 20th century there were individuals still using it prior to the conventional literacy increase due to the general education. Similar knot scripts can be found in several cultures around the globe. The article encompasses a study of previous researches and evidence in periodicals, Latvian community in Lithuania, education of commoners in Latvia, reciprocal comparison of the Latvian knot script writing systems, interv…

LiteratureEngineeringFolkloreclew; folk songs; knot alphabet; knot records; knot script; knot writing; Latvia; Latvian language; Lithuania; quipu; song ball; song clew; Vismantai; writing system; yarn ballbusiness.industryMetaphormedia_common.quotation_subjectGlobeLatvianWitnesslanguage.human_languageLiteracymedicine.anatomical_structureWriting systemmedicinelanguagebusinessKnot (mathematics)media_commonEducation Reform in Comprehensive School: Education Content Research and Implementation Problems
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Correction to: Ernst Mach’s „Bekehrung“ zum Atomismus/Ernst Mach’s “Conversion” to Atomism – A Dialogue Between Mach and Popper-Lynkeus by Otto Blüh

2019

Otto Bluh was a great admirer of Ernst Mach’s and contributed a number of papers to Machian scholarship. It is believed that he wrote this skit around 1966, perhaps to coincide with the celebration of the 50th anniversary of Mach’s death and most likely for Bluh’s own amusement, as it was never published. It consists of an imaginary conversation in pseudo-Viennese dialect, between Mach and his friend, Josef Popper-Lynkeus based on the questionable tale of Mach’s conversion to atomism. This paper includes a brief introduction to the skit as well as its transcription and translation into English, published for the first time. It was also dramatized for the first time in occasion of the Ernst …

Literaturebusiness.industrymedia_common.quotation_subjectPhilosophyAmusementScholarshipsymbols.namesakeAtomism (social)Mach numberTranscription (linguistics)symbolsConversationbusinessThe Imaginarymedia_common
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Johana Kristofa Broces (Brotze, 1742-1823) dzīvesgājums un viņa rokrakstu kolekcija LU Akadēmiskajā bibliotēkā

2013

ANOTĀCIJA Promocijas darbs „Johana Kristofa Broces (Brotze, 1742-1823) dzīvesgājums un viņa rokrakstu kolekcija LU Akadēmiskajā bibliotēkā” ir interdisciplinārs humanitāro zinātņu pētījums, kas veltīts Latvijas kultūrvēsturē īpaši nozīmīgas personības biogrāfijas rekonstrukcijai un viņa darbības analīzei, un tādējādi risina bibliotēku vēstures, grāmatniecības, avotpētniecības, historiogrāfijas problēmas. Nav šaubu par to, ka pedagogs, avotpētnieks un bibliofils Broce ir viens no visspilgtākajiem Apgaismības laikmeta darbiniekiem Latvijā un Baltijā. Viņa rokrakstu un grāmatu kolekcija (kopskaitā 599 sējumi) ir kļuvusi par LU Akadēmiskās bibliotēkas dārgumu, vēsturiskās kontinuitātes apliecin…

LiteratūrzinātneLatvian historiographyValodu un kultūras studijas dzimtās valodas studijas un valodu programmasBibliotēkzinātneLibrary scienceFiloloģijarokrakstu kolekcijasJohans Kristofs Broce - biogrāfijamanuscript collectionavotpētniecībabibliotēku vēstureresearch of primary sourcesLatvijas historiogrāfijaJohann Christoph Brotze - Biography
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