Search results for "script"
showing 10 items of 5143 documents
Aspectos geográficos en la obra de Antonio Bordazar De Artzau, Impresor erudito valenciano del siglo XVIII
1987
EN EL PERESENTE ARTICULO SE HACE UN RECORRIDO POR LA OBRA MANUSCRITA DEL IMPRESOR ANTONIO BORDAZAR DE ARTAZU, ULTIMO DE LOS MIEMBROS DEL MOVIMIENTO DE RENOVACION CIENTIFICA QUE TUVO LUGAR EN VALENCIA EN EL TRANSITO DEL SIGLO XVII AL XVIII. SE ATIENDE FUNDAMENTALMENTE A SU CONTENIDO GEOGRAFICO, INTENTANDO PONER DE RELIEVE LAS INFLUENCIAS RECIBIDAS DE LOS AUTORES MAS SIGNIFICATIVOS DE LA EPOCA Y DE LOS ASPECTOS MAS VALIOSOS DE LA MISMA, ESENCIALMENTE EN SU VERTIENTE CARTOGRAFICA. POR MEDIO DE TODO ELLO SE PRETENDE SU VALORACION ADECUADA Y UN ACERCAMIENTO A LOS PLANTEAMIENTOS DE LA GEOGRAFIA A COMIENZOS DEL SIGLO QUE MARCARIA SU INFLEXION DESDE POSICIONES MATEMATICAS Y CIENTIFICAS HACIA LA LIN…
2021
This study investigated the reasons that leaders have given for their leader role occupancy. By using a mixed-method approach and large leader data, we aimed to provide a more nuanced picture of how leader positions are occupied in real life. We examined how individual leadership motivation may associate with other reasons for leader role occupancy. In addition, we aimed to integrate the different reasons behind leader role occupancy into the framework of sustainable leader careers and its two indicators: leader’s health (occupational well-being) and performance (measured indirectly as followers’ occupational well-being). The survey data consisted of 1,031 leaders from various sectors of wo…
Seawater carbonate chemistry and kelp densities and coral coverages at three study locations and photosynthesis and calcification of corals measured …
2021
Ocean warming is altering the biogeographical distribution of marine organisms. In the tropics, rising sea surface temperatures are restructuring coral reef communities with sensitive species being lost. At the biogeographical divide between temperate and tropical communities, warming is causing macroalgal forest loss and the spread of tropical corals, fishes and other species, termed “tropicalization”. A lack of field research into the combined effects of warming and ocean acidification means there is a gap in our ability to understand and plan for changes in coastal ecosystems. Here, we focus on the tropicalization trajectory of temperate marine ecosystems becoming coral-dominated systems…
Gatekeeper of pluripotency: A common Oct4 transcriptional network operates in mouse eggs and embryonic stem cells
2011
Abstract Background Oct4 is a key factor of an expanded transcriptional network (Oct4-TN) that governs pluripotency and self-renewal in embryonic stem cells (ESCs) and in the inner cell mass from which ESCs are derived. A pending question is whether the establishment of the Oct4-TN initiates during oogenesis or after fertilisation. To this regard, recent evidence has shown that Oct4 controls a poorly known Oct4-TN central to the acquisition of the mouse egg developmental competence. The aim of this study was to investigate the identity and extension of this maternal Oct4-TN, as much as whether its presence is circumscribed to the egg or maintained beyond fertilisation. Results By comparing …
Measuring the social impact of research in Paediatric Dentistry: An Altmetric study.
2019
Background: Traditional metrics have been extensively used to evaluate the scientific performance. Despite being widespread accepted, citation-based metrics are not able to describe the social impact of research. A diverse metric, Altmetric, was proposed to overcome those limitations. Aim: This study aims to analyse the social impact of research in the field of paediatric dentistry and to assess if a correlation exists between the JCR citations, the AAS score, and the recently released Dimensions citation count. Design: A bibliometric study was conducted on the four journals related to Paediatric Dentistry listed in the JCR from 2014 to 2017. Descriptive statistics was used to describe the …
Effectiveness of Safety Warnings in Atypical Antipsychotic Drugs
2009
Studies conducted to obtain drug authorization are often of short duration and based on small sample sizes in selected populations. Policies on drug safety rely on the validity of the methods used to achieve rapid and effective communication of new information. No formal evaluation has ever been made of the Spanish communications system, although indirect data have raised questions about its effectiveness.To evaluate the impact of two safety warnings issued by the Spanish Drug Agency, and of a later prior authorization requirement involving the use of atypical antipsychotic drugs in the elderly.The study was based on a time-series analysis constructed with data corresponding to monthly invo…
Glimpses of the Hereafter in the Late-Medieval Thet Freske Riim
2014
The article analyzes a passage of the narrative poem Thet Freske Riim, one of the few non-legal texts preserved in Old Frisian. The passage in question is a digression describing the Joys of Heaven and the Horrors of Hell, which so far has attracted little attention in the scholarly literature on medieval accounts of the hereafter. The representations of the afterlife and its realms circulating in Medieval Europe draw inspiration from a wide body of both orthodox and apocryphal literature on ecstatic dreams, of which one of the most influential work is the Visio Sancti Pauli or Apocalypse of Paul. The study aims to identify – in the examined passage – themes and features of otherworldly lit…
Le iscrizioni runiche sullo sfondo della cultura Frisone altomedievale
2000
The study offers a critical edition of the Old Frisian runic corpus, together with a linguistic and philological analysis of the inscriptions examined, also in the light of their context of occurrence,
Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.
2001
UDP-glucuronosyltransferases (UGTs) form a multigenic family of enzymes involved in the biotransformation and elimination of numerous endo- and xenobiotic compounds. Beside the diverse UGT isoforms present in the liver as well as in other tissues, the UGT2A1 isoform, also called olfactory UGT, was initially thought to be expressed in the nasal epithelium only. In this work, we demonstrate the UGT2A1 mRNA expression in the olfactory bulb, using in situ hybridization and quantitative reverse transcription-polymerase chain reaction (RT-PCR) techniques. Within the epithelium, UGT2A1 mRNA is mainly found in the sustentacular cells and to a lesser extent in Bowman's gland cells. Moreover, in situ…
(2'-5')Oligoadenylate and intracellular immunity against retrovirus infection.
1992
1. 1. The double-stranded RNA-dependent 2′,5′-oligoadenylate (2–5A) synthetase/ribonuclease L (RNase L) system plays an essential role in the establishment of the antiviral state of a cell exposed to virus infection. 2. 2. Until recently, the application of 2–5A derivatives to reinforce this system seemed to be limited mainly due to the low specificity of RNase L for viral RNA. 3. 3. Two new strategies have been developed which yield a selective antiviral effect of 2–5As at least against human immunodeficiency virus-1 (HIV-1) infection: (i) an “intracellular immunization” appproach using 2-5A synthetase cDNA linked to HIV trans -acting response element (TAR) and (ii) inhibition of retrovira…