Search results for "script"
showing 10 items of 5143 documents
Q-nexus
2018
Q-nexus is a comprehensive software package for ChIP-nexus data that exploits the random barcodes for selective removal of PCR duplicates and for quality control.
Effects of Kolmogorov complexity present in inductive inference as well
1997
For all complexity measures in Kolmogorov complexity the effect discovered by P. Martin-Lof holds. For every infinite binary sequence there is a wide gap between the supremum and the infimum of the complexity of initial fragments of the sequence. It is assumed that that this inevitable gap is characteristic of Kolmogorov complexity, and it is caused by the highly abstract nature of the unrestricted Kolmogorov complexity.
Inductive inference of recursive functions: Complexity bounds
2005
This survey includes principal results on complexity of inductive inference for recursively enumerable classes of total recursive functions. Inductive inference is a process to find an algorithm from sample computations. In the case when the given class of functions is recursively enumerable it is easy to define a natural complexity measure for the inductive inference, namely, the worst-case mindchange number for the first n functions in the given class. Surely, the complexity depends not only on the class, but also on the numbering, i.e. which function is the first, which one is the second, etc. It turns out that, if the result of inference is Goedel number, then complexity of inference ma…
Non-intersecting Complexity
2006
A new complexity measure for Boolean functions is introduced in this article. It has a link to the query algorithms: it stands between both polynomial degree and non-deterministic complexity on one hand and still is a lower bound for deterministic complexity. Some inequalities and counterexamples are presented and usage in symmetrisation polynomials is considered.
An international perspective on hospitalized patients with viral community-acquired pneumonia
2019
Background Who should be tested for viruses in patients with community acquired pneumonia (CAP), prevalence and risk factors for viral CAP are still debated. We evaluated the frequency of viral testing, virus prevalence, risk factors and treatment coverage with oseltamivir in patients admitted for CAP. Methods Secondary analysis of GLIMP, an international, multicenter, point-prevalence study of hospitalized adults with CAP. Testing frequency, prevalence of viral CAP and treatment with oseltamivir were assessed among patients who underwent a viral swab. Univariate and multivariate analysis was used to evaluate risk factors. Results 553 (14.9%) patients with CAP underwent nasal swab. Viral CA…
Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNA s
2018
Abstract Learning is essential for survival and is controlled by complex molecular mechanisms including regulation of newly synthesized mRNAs that are required to modify synaptic functions. Despite the well‐known role of RNA‐binding proteins (RBPs) in mRNA functionality, their detailed regulation during memory consolidation is poorly understood. This study focuses on the brain function of the RBP Gadd45α (growth arrest and DNA damage‐inducible protein 45 alpha, encoded by the Gadd45a gene). Here, we find that hippocampal memory and long‐term potentiation are strongly impaired in Gadd45a‐deficient mice, a phenotype accompanied by reduced levels of memory‐related mRNAs. The majority of the Ga…
Common variants conferring risk of schizophrenia
2009
Schizophrenia is a complex disorder, caused by both genetic and environmental factors and their interactions. Research on pathogenesis has traditionally focused on neurotransmitter systems in the brain, particularly those involving dopamine. Schizophrenia has been considered a separate disease for over a century, but in the absence of clear biological markers, diagnosis has historically been based on signs and symptoms. A fundamental message emerging from genome-wide association studies of copy number variations (CNVs) associated with the disease is that its genetic basis does not necessarily conform to classical nosological disease boundaries. Certain CNVs confer not only high relative ris…
I codici in scrittura latina di Alessandro Farnese (1520-1589) a Caprarola e al Palazzo della Cancelleria nel 1589
2016
This article analyses the contents of the manuscripts in Latin script found at the Villa Farnese of Caprarola and the Palazzo della Cancelleria of Rome at the death of Cardinal Alessandro Farnese (1520-1589). They were inventoried by Claudio Tobalducci, librarian to the Cardinal; the inventories were edited by Francois Fossier. Although the manuscript collections seem neither organic nor systematically constituted by the Cardinal (the volumes were mainly borrowed from the great Farnese library in the Palazzo Farnese in Rome), the manuscripts were used by the Cardinal in the last years of his life. They shed light on at least some of the personal interests of this important ecclesiastical, p…
La escritura en la Cartuja (análisis diacrónico a través de las constituciones)
1983
The southernmost Miocene occurrence of the last European herpetotheriid Amphiperatherium frequens (Metatheria, Mammalia)
2012
Abstract The present work provides for the first time a detailed description of teeth attributable to metatherians in the Miocene fossil record of Spain, and justifies their generic and specific ascription. The fossil elements found correspond to Amphiperatherium frequens, the last herpetotheriid that inhabited Europe. This is so far the southernmost occurrence of this species, thus showing that its geographic range extended further southward than previously thought.