Search results for "script"

OPLA scaffold, collagen I, and horse serum induce a higher degree of myogenic differentiation of adult rat cardiac stem cells

2009

In the last few years, a major goal of cardiac research has been to drive stem cell differentiation to replace damaged myocardium. Several research groups have attempted to differentiate potential cardiac stem cells (CSCs) using bi- or three-dimensional systems supplemented with growth factors or molecules acting as differentiating substances. We hypothesize that these systems failed to induce a complete differentiation because they lacked an architectural space. In the present study, we isolated a pool of small proliferating and fibroblast-like cells from adult rat myocardium. The phenotype of these cells was assessed and the characterized cells were cultured in a collagen I/OPLA scaffold …

Cultivating the Installed Base: The Introduction of e-Prescription in Greece

2017

In this chapter we explore the surprisingly swift deployment of a national e-prescription service in Greece. We position e-prescribing within the overall Greek health system and we describe how the new electronic service evolved to inscribe specific prescribing policies, to provide clinical decision support and to facilitate the processes and roles of policy and financing stakeholders. We identify how a series of pragmatic decisions allowed building upon a “good-enough” installed base by exploiting its latent potential without perpetuating all of its weaknesses, and by being responsive to exogenous shifts. These tactical decisions, were supported by a favourable and enabling combination of …

Reducing Local Alphabet Size in Recognizable Picture Languages

2021

A recognizable picture language is defined as the projection of a local picture language defined by a set of two-by-two tiles, i.e. by a strictly-locally-testable (SLT) language of order 2. The family of recognizable picture languages is also defined, using larger k by k tiles, \(k>2\), by the projection of the corresponding SLT language. A basic measure of the descriptive complexity of a picture language is given by the size of the SLT alphabet using two-by-two tiles, more precisely by the so-called alphabetic ratio of sizes: SLT-alphabet/picture-alphabet. We study how the alphabetic ratio changes moving from two to larger tile sizes, and we obtain the following result: any recognizable pi…

<strong>New tool useful for drug discovery validated through benchmark datasets</strong>

2018

Atomic Weighted Vectors (AWVs) are vectors that contain the codified information of molecular structures, which can apply to a set of Aggregation Operators (AOs) to calculate total and local molecular descriptors (MDs). This article presents an exploratory study of a new tool useful for drug discovery using different datasets, such as DRAGON and Sutherland’s datasets, as well as their comparison with other well-known approaches. In order to evaluate the performance of the tool, several statistics and QSAR/QSPR experiments were performed. Variability analyses are used to quantify the information content of the AWVs obtained from the tool, by the way of an information theory-based algorithm. …

Extraction of Endmembers from Spectral Mixtures

1999

Abstract Linear spectral mixture modeling (LSMM) divides each ground resolution element into its constituent materials using endmembers which represent the spectral characteristics of the cover types. However, it is difficult to identify and estimate the spectral signature of pure components or endmembers which form the scene, since they vary with the scale and purpose of the study. We propose three different methods to estimate the spectra of pure components from a set of unknown mixture spectra. Two of the methods consist in different optimization procedures based on objective functions defined from the coordinate axes of the dominant factors. The third one consists in the design of a neu…

Working with (too) Few Samples

2018

This paper is concerned with gene set differential expression analysis. We compare the transcriptomic behaviour of each gene set between different experimental conditions.The gene set is previously defined. It has been used a gene set collection downloaded from Gene Ontology.A randomization test is proposed and compared with other previous procedures using a RNA-seq experiment of colorectal cancer (CRC).

INVESTIGATION OF BIOTIC STRESS RESPONSES IN FRUIT TREE CROPS USING META-ANALYTICAL TECHNIQUES.

2020

In recent years, RNA sequencing and analysis using Next Generation Sequencing (NGS) methods have enabled to understand the gene expression pertaining to plant biotic and abiotic stress conditions in both quantitative and qualitative manner. The large number of transcriptomic works published in plants requires more meta-analysis studies that would identify common and specific features in relation of the high number of objective studies performed at different developmental and environmental conditions. Meta-analysis of transcriptomic data will identify commonalities and differences between differentially regulated gene lists and will allow screen which genes are key players in gene-gene and p…

Valorizzazione della biodiversità frutticola in Sicilia: caratterizzazione qualitativa di vecchie varietà di melo.

2010

Development of Sicilian bean core collection using morphological descriptors

2018

Different species and varieties of bean, spread in Sicily, are representative of local agricultural practices, as result of a careful exploration. Many landraces have become obsolete due to the spread of commercial varieties, but are still cultivated in small areas of Nebrodi Mountains (ME-Italy) and are endangered. The Sicilian bean landraces are often poorly known but represent a genetic heritage to be preserve and to enhance. The ex situ conservation of Sicilian bean landraces was carried out in “Living Plants Germplasm Bank” of Ucria (ME-Italy), founded by the Nebrodi Regional Park, and in “Sicilian Plant Germplasm Repository” of STEBICEF Department - University of Palermo. Within ex si…

First evidence of an egg-laying attempt of feral Trachemys scripta (Schoepff, 1792) in Sicily (Lake Pergusa, Italy)

2020

First evidence of an egg-laying attempt of feral Trachemys scripta in Sicily