Search results for "script"
showing 10 items of 5143 documents
Terminal tendon cell differentiation requires the glide/gcm complex.
2004
International audience; Locomotion relies on stable attachment of muscle fibres to their target sites, a process that allows for muscle contraction to generate movement. Here, we show that glide/gcm and glide2/gcm2, the fly glial cell determinants, are expressed in a subpopulation of embryonic tendon cells and required for their terminal differentiation. By using loss-of-function approaches, we show that in the absence of both genes, muscle attachment to tendon cells is altered, even though the molecular cascade induced by stripe, the tendon cell determinant, is normal. Moreover, we show that glide/gcm activates a new tendon cell gene independently of stripe. Finally, we show that segment p…
New molecular aspects of regulation of mitochondrial activity by fenofibrate and fasting
2000
Abstract Fenofibrate and fasting are known to regulate several genes involved in lipid metabolism in a similar way. In this study measuring several mitochondrial enzyme activities, we demonstrate that, in contrast to citrate synthase and complex II, cytochrome c oxidase (COX) is a specific target of these two treatments. In mouse liver organelles, Western blot experiments indicated that mitochondrial levels of p43, a mitochondrial T3 receptor, and mitochondrial peroxisome proliferator activated receptor (mt-PPAR), previously described as a dimeric partner of p43 in the organelle, are increased by both fenofibrate and fasting. In addition, in PPARα-deficient mice, this influence was abolishe…
Heat shock factor 2 is a stress-responsive mediator of neuronal migration defects in models of fetal alcohol syndrome
2014
Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development defects induced by maternal alcohol consumption during pregnancy are unclear. We used normal and Hsf2-deficient mice and cell systems to uncover a pivotal role for heat shock factor 2 (HSF2) in radial neuronal migration defects in the cortex, a hallmark of fetal alcohol exposure. Upon fetal alcohol exposure, HSF2 is essential for the triggering of HSF1 activation, which is accompanied by distinctive post-translational modifications, and HSF2 steers the formation of atypical alcohol-specific HSF1–HSF2 heterocomplexes. This perturbs the in vivo bindi…
Une seconde vie pour les archives archéologiques : les amateur.e.s à la rescousse !
2019
Action en nullité. La prescription de l'action en nullité n'est pas la prescription de droit commun
2010
International audience; (Com. 30 mars 2010, pourvoi n° 08-17.556, arrêt n° 372 F-D, BNP Paribas c/ SNC Plaisant frères, D. 2010. Actu. 1017, obs. A. Lienhard ; cette Revue 2010. 433, obs. J.-L. Vallens)
Action en nullité. Délai d'exercice. L'action en nullité peut être intentée par ses titulaires aussi longtemps qu'ils restent en fonction
2011
International audience; (Com., 21 sept. 2010, n° 08-21.030, arrêt n° 875 F-P+B, Leyraud c/ SELARL Mary-Laure Gastaud, D. 2010. 2221, obs. A. Lienhard ; Rev. sociétés 2011. 311, note C. Boillot ; RTD com. 2010. 797, obs. J.-L. Vallens ; JCP E 2010, 1946, note S. Reifegerste ; Gaz. Pal. 7-8 janv. 2011, p. 37, note Ph. Roussel Galle)
Contrats publiés au RCS. Report de l'inscription par suite du transfert du siège de la société débitrice. Conséquences sur la demande de restitution …
2018
International audience; (Com. 24 mai 2018, n° 16-28.083, arrêt n° 518 FS-D, Sté Banque populaire Alsace Lorraine Champagne c/ Sté Petite Mécanique appliquée et a.)
Créances fiscales. Admission par le juge-commissaire, Effets, Interversion de la prescription (non)
1993
International audience; (CE 3 juin 1992, Req. n° 67-215, ministre de l'Economie, des Finances et du Budget c/ M. Drux)
Poursuites individuelles. Hypothèque judiciaire provisoire et inscription définitive après l'ouverture d'une liquidation judiciaire
2016
International audience; (Com. 3 mai 2016, n° 14-21.556, arrêt n° 409 FS-P+B, Sté Finansiel Stabilitet A/S c/ M.Michael C. et a., D. 2016. 996)