Search results for "script"
showing 10 items of 5143 documents
Animal musicians in illuminated manuscripts (1300-1450)
2014
International audience; The illustrations of illuminated manuscripts between 1300 and 1450 featured a very large number of animal musicians. They were set in the marginal borders of the pages, and framed the text and miniature with their musical sonorities. Along with King David, animals were the main musicians featured in medieval illuminations, far more numerous than angels and minstrels. The monkey, dog, fox and half-animal, half-human hybrid creatures were the " champions " of instrumental music. At the crossroads of history and art history, musicology and literature, their representations suggest that we identify typologies of books, animals and instruments. They raise several question…
Preclinical characterization of antagomiR-218 as a potential treatment for myotonic dystrophy
2021
Myotonic dystrophy type 1 (DM1) is a rare neuromuscular disease caused by expansion of unstable CTG repeats in a non-coding region of the DMPK gene. CUG expansions in mutant DMPK transcripts sequester MBNL1 proteins in ribonuclear foci. Depletion of this protein is a primary contributor to disease symptoms such as muscle weakness and atrophy and myotonia, yet upregulation of endogenous MBNL1 levels may compensate for this sequestration. Having previously demonstrated that antisense oligonucleotides against miR-218 boost MBNL1 expression and rescue phenotypes in disease models, here we provide preclinical characterization of an antagomiR-218 molecule using the HSALR mouse model and patient-d…
Explaining information technology users’ ways of mitigating technostress
2017
Technostress refers to the inability of an individual to deal with information technology (IT) in a healthy manner. Researchers, practitioners, and medical professionals have emphasized the omnipresence of technostress and its severe outcomes, including poor well-being and burnout. Despite the importance of the phenomenon, prior research has paid limited attention to how technostress can be mitigated. The few existing studies examine organizational mitigation mechanisms, but we could not find any studies that focus on individual IT users’ own ways of mitigating technostress outside of work. To address the research gap, we conducted a qualitative study to uncover users’ ways of mitigating te…
The Effect of Textual Producer-Generated Descriptions on Demand of Mobile Applications
2017
We analyze the impact of different app description characteristics on app demand on the basis of panel data for six months and 1081 distinct apps. We use several text mining techniques in order to operationalize the descriptions’ textual characteristics. The extracted variables are then used in an econometric investigation to examine their impact on apps’ downloads. Our results provide evidence that app descriptions have an effect on demand. Apps with upfront price should be described in a neutral tone. Apps without an upfront price but with in-app purchase option should be offered with rather short descriptions that are written in a formal and subjective style. peerReviewed
X-Ray structure, Hirshfeld analysis and DFT studies of two new hits of triazolyl-indole bearing alkylsulfanyl moieties
2021
Two new hits of triazolyl-indole containing two different alkylsulfanyl analogues named tert-butyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 2, and ethyl 2-((4-amino-5-(1H-indol-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetate 3 were synthesized via reaction of 4-amino-5-(1H-indol-2-yl)-1,2,4-triazol-3(2H)-thione 1 with tert-butyl bromoacetate and ethyl chloroacetate in the presence of base (Et3N). The molecular structure of 2, and 3 was confirmed by single-crystal X-ray diffraction and 1H/13C- NMR spectroscopic techniques. In compound 2, the molecular packing depends on significant O...H (9.3%), N...H (12.4%) and S...H (3.1%) as well as relatively weak C...H (14.1%), S...C (…
Condictio e causa actionis
2014
Since the publication of Julius Baron’s book about the condictiones in 1881, the condictio of the Roman formulary procedure is considered as an ‘abstract’ action. In Baron’s opinion this peculiar nature was due to the fact that its formula never mentioned – and could not mention – the basis of the claim neither in its intentio, nor in a demonstratio, nor in a praescriptio. By considering the two formulae of condictio certae pecuniae recorded in TPSulp. 31, this paper focuses on the concept of causa actionis in order to call into question the gospel of the ‘abstractness’ of the formular condictio. A new analysis of the sources leads to the conclusion that in the formulary procedure the condi…
Audiodescription et problématique de la traduction de contenus sexuels : le cas de La vie d’Adèle d’Abdellatif Kechiche
2018
L’audiodescription est une modalité émergente de traduction audiovisuelle dont l’objectif principal est de rendre accessible à des personnes malvoyantes ou non voyantes des films, de façon à ce qu’elles puissent comprendre et profiter du film comme un spectateur qui peut voir les images. Dans cet article, nous présentons une étude sur un sujet considéré tabou : la traduction d’images de contenu sexuel en mots. Dans un premier temps, nous avons identifié les scènes de contenu sexuel explicite dans le film français La vie d’Adèle (Kechiche, 2013). Nous avons analysé l’audiodescription qui les accompagne et déterminé les stratégies traductologiques utilisées pour le faire. Nous avons observé d…
Heavy Metals and Metalloids as Autophagy Inducing Agents: Focus on Cadmium and Arsenic
2012
In recent years, research on the autophagic process has greatly increased, invading the fields of biology and medicine. Several markers of the autophagic process have been discovered and various strategies have been reported studying this molecular process in different biological systems in both physiological and stress conditions. Furthermore, mechanisms of metalloid- or heavy metal-induced toxicity continue to be of interest given the ubiquitous nature and distribution of these contaminants in the environment where they often play the role of pollutants of numerous organisms. The aim of this review is a critical analysis and correlation of knowledge of autophagic mechanisms studied under …
Jan Hus – prekursor reformacji XVI wieku
2017
Problem artykułu został rozwinięty w dwóch punktach. W punkcie pierwszym ukazano tło historyczne życia i działalności Jana Husa: dane biograficzne, stosunek Husa do schizmy w Kościele, do sytuacji politycznej i społecznej w Czechach oraz sobór w Konstancji. W punkcie drugim przedstawiono główne reformatorskie postulaty teologii Jana Husa: rozumienie autorytetu źródeł wiary – zwłaszcza autorytetu Pisma Świętego, naukę o Kościele i predestynacji oraz nauczanie o papiestwie.
De Stijl e l'architettura. L'Hotel particulièr, trascrizioni grafiche De Stijl and architecture. Hotel particulièr, graphic transcriptions
2016
Questo studio è un punto di vista sulle sperimentazioni condotte dal gruppo De Stijl sull’architettura attraverso l’analisi di un’opera mai realizzata, l’Hôtel particulièr progettato nel 1923 da Cornelis van Eesteren e Theo van Doesburg. Gli studi su De Stijl hanno già tracciato il percorso critico del movimento olandese ma questo lavoro vuole indagare un progetto che è rimasto, nella bibliografia esistente, nella fissità delle sue rappresentazioni e mai indagato attraverso lo strumento del disegno, atto interpretativo e critico dell’architettura che comprende, traduce e trascrive l’idea. This study is a point of view on experimentations made by De Stijl group about architecture through the…