Search results for "seal"

showing 10 items of 244 documents

Novel Pulmonary Vasculitis with Splendore-Hoeppli Reaction in Grey Seals (Halichoerus grypus) Associated with Otostrongylus circumlitus Infection.

2019

Summary Lungworm infection in seals is an important cause of morbidity and mortality, inducing bronchopneumonia and affecting population dynamics in some areas of the world. We present a series of cases of lungworm infection in grey seals (Halichoerus grypus) associated with novel, significant and unusual pulmonary vascular changes. Grey seals (n = 180) that were stranded, in rehabilitation or in long-term captivity in the UK were subjected to post-mortem examination between 2012 and 2018. Lung tissue was collected from 47 individuals for histopathological examination. Polymerase chain reaction (PCR) on formalin-fixed and paraffin wax-embedded (FFPE) material was attempted for parasite iden…

Lung DiseasesVasculitismedicine.medical_specialtyPathology040301 veterinary sciencesSeals EarlessPopulation030308 mycology & parasitologyPathology and Forensic Medicine0403 veterinary science03 medical and health sciencesmedicineAnimalseducationStrongylida Infections0303 health scienceseducation.field_of_studyGeneral Veterinarybusiness.industryHistology04 agricultural and veterinary sciencesmedicine.diseaseMetastrongyloideamedicine.anatomical_structureGranulomaHistopathologyEosinophilic vasculitisVasculitisLungwormbusinessBlood vesselJournal of comparative pathology
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Rod-cone based color vision in seals under photopic conditions

2016

Marine mammals have lost the ability to express S-cone opsin, and possess only one type of M/L-cone in addition to numerous rods. As they are cone monochromats they should be color blind. However, early behavioral experiments with fur seals and sea lions indicated discrimination ability between many shades of grey and blue or green. On the other hand, most recent training experiments with harbor seals under "mesopic" conditions demonstrated rod based color blindness (Scholtyssek et al., 2015). In our experiments we trained two harbor seals (Phoca vitulina) and two South African fur seals (Arctocephalus pusillus) with surface colors under photopic conditions. The seals had to detect a triang…

Male0301 basic medicineBrightnessMesopic visionColor visionmedia_common.quotation_subjectPhocaLuminancePhocaContrast Sensitivity03 medical and health sciences0302 clinical medicineOpticsAnimalsContrast (vision)Mathematicsmedia_commonColor Visionbiologybusiness.industryFur Sealsbiology.organism_classificationSensory SystemsOphthalmology030104 developmental biologySensory ThresholdsHarbor sealFemalebusiness030217 neurology & neurosurgeryPhotoreceptor Cells VertebratePhotopic visionVision Research
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Identification of Novel pro-α2(IX) Collagen Gene Mutations in Two Families with Distinctive Oligo-Epiphyseal Forms of Multiple Epiphyseal Dysplasia

1999

Multiple epiphyseal dysplasia (MED) is a genetically heterogeneous disorder with marked clinical and radiographic variability. Traditionally, the mild "Ribbing" and severe "Fairbank" types have been used to define a broad phenotypic spectrum. Mutations in the gene encoding cartilage oligomeric-matrix protein have been shown to result in several types of MED, whereas mutations in the gene encoding the alpha2 chain of type IX collagen (COL9A2) have so far been found only in two families with the Fairbank type of MED. Type IX collagen is a heterotrimer of pro-alpha chains derived from three distinct genes-COL9A1, COL9A2, and COL9A3. In this article, we describe two families with distinctive ol…

MaleAdolescentRNA SplicingMutantGene mutationBiologyOsteochondrodysplasiasmedicine.disease_causeMultiple epiphyseal dysplasia03 medical and health sciencesExon0302 clinical medicineOsteoarthritismedicineGeneticsHumansGenetics(clinical)Genetic TestingOsteochondrodysplasiaMultiple epiphyseal dysplasiaGene mutationAlleleChildPolymorphism Single-Stranded ConformationalGenetics (clinical)030304 developmental biologyGenetics0303 health sciencesMutationType IX collagenGenetic heterogeneitymedicine.diseaseOsteochondrodysplasiaPedigreeRadiographyCartilageChild PreschoolMutationFemaleEpiphysesProcollagen030217 neurology & neurosurgeryResearch ArticleThe American Journal of Human Genetics
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Polychlorinated diphenyl ethers, dibenzo-p-dioxins, dibenzofurans and biphenyls in seals and sediment from the Gulf of Finland.

1997

Polychlorinated diphenyl ethers (PCDEs), 2,3,7,8-substituted polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs), and polychlorinated biphenyls (PCBs) were analyzed in seals from the Gulf of Finland and in sediments from the Gulf of Finland and near Gotland. The sediments included one surface core from both sampling sites. The seal material consisted of 14 ringed seals and 6 grey seals that all were found dead and examined for pathology. The main aims were to scrutinize levels and patterns of PCDEs for the first time in seals from the Baltic Sea and to estimate whether chlorinated compounds mentioned have an influence on an exceptional high mortality that occurred among ring…

MaleAgingEnvironmental EngineeringYounger agePolychlorinated DibenzodioxinsSeals EarlessHealth Toxicology and MutagenesisNutritional StatusGas Chromatography-Mass SpectrometryPolychlorinated diphenyl ethersDry weightBlubberEnvironmental ChemistryAnimalsFinlandBenzofuransEcologyChemistryHigh mortalityPublic Health Environmental and Occupational HealthSedimentNutritional statusGeneral MedicineGeneral ChemistryPollutionPolychlorinated BiphenylsBaltic seaAdipose TissueEnvironmental chemistryFemaleWater Pollutants ChemicalChemosphere
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Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications

1990

(1990). Therapeutic Perspectives in Psychoneuroendocrinimmunology(PNEI): Potential Role of Phosphatidylserine in Neuroendocrine-Immune Communications. International Journal of Neuroscience: Vol. 51, No. 3-4, pp. 299-301.

MaleAgingHypothalamo-Hypophyseal SystemGonadotropin RHbusiness.industryGeneral NeurosciencePhosphatidylserinesGeneral MedicinePhosphatidylserineInterleukine 2RatsAntibody productionchemistry.chemical_compoundImmune systemchemistryMemoryImmunologyAnimalsLearningMedicineFemaleProestrusbusinessNeuroscienceReceptors LHRHInternational Journal of Neuroscience
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Epiphany root canal sealer prepared with resinous solvent is irritating to rat subcutaneous tissues.

2011

Objective: This study assessed the biocompatibility of the Epiphany endodontic sealer prepared with resinous solvent of Epiphany system (Thinning resin) in rat subcutaneous tissues. Study Design: Polyethylene tubes were filled with the sealer and 4 groups were established: GI, Epiphany prepared with 1 drop of resinous solvent (RS); GII, Epiphany prepared with 1 drop of RS and photoactivated; GIII, Epiphany associated with self-etch primer and prepared with 1 drop of RS; GIV, Epiphany associated with self-etch primer, prepared with 1 drop of RS and photoactivated. The filled tubes were implanted into 4 different regions of the dorsum of 20 adult male rats. Results: After 7, 14 and 21 days, a…

MaleBiocompatibilityAdult maleRoot canalmedia_common.quotation_subjectDentistryEndodonticsRoot Canal Filling MaterialsSubcutaneous TissueMaterials TestingmedicineAnimalsRats WistarGeneral Dentistrymedia_commonInflammationChemistrybusiness.industryChronic inflammatory reaction:CIENCIAS MÉDICAS [UNESCO]Epiphany sealerRatsSolventResins Syntheticmedicine.anatomical_structureOtorhinolaryngologyEpiphanyUNESCO::CIENCIAS MÉDICASSolventsSurgeryResearch-ArticlebusinessSubcutaneous tissueMedicina oral, patologia oral y cirugia bucal
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The spondylometaphyseal dysplasias. A tentative classification.

1991

The spondylometaphyseal dysplasias constitute a very complex group of disorders. In addition to the Kozlowski type, three subgroups can be distinguished by the appearance of the femoral neck. In the first group (A) the changes are severe with absent ossification of the femoral neck and coxa vara. In the second group (B) the changes of the femoral neck are moderate and in the third (C) mild metaphyseal irregularities are only visible. This classification is not definitive but tries to put order in this confusing section of constitutional bone diseases.

MaleBone diseaseAdolescentCoxa varaOsteochondrodysplasiasmedicineHumansRadiology Nuclear Medicine and imagingChildFemoral neckbusiness.industryOssificationFemur NeckInfantAnatomymedicine.diseaseHandmedicine.anatomical_structureSpondylometaphyseal dysplasiaDysplasiaChild PreschoolPediatrics Perinatology and Child HealthFemaleSpinal Diseasesmedicine.symptombusinessPediatric radiology
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Investigating individual stress reactivity: High hair cortisol predicts lower acute stress responses

2020

Identifying individual differences in stress reactivity is of particular interest in the context of stress-related disorders and resilience. Previous studies already identified several factors mediating the individual stress response of the hypothalamus-pituitary-adrenal axis (HPA). However, the impact of long-term HPA axis activity on acute stress reactivity remains inconclusive. To investigate associations between long-term HPA axis variation and individual acute stress reactivity, we tested 40 healthy volunteers for affective, endocrine, physiological, and neural reactions to a modified, compact version of the established in-MR stress paradigm ScanSTRESS (ScanSTRESS-C). Hair cortisol con…

MaleCingulate cortexHydrocortisoneEndocrinology Diabetes and MetabolismIndividualityPituitary-Adrenal SystemACTIVATIONFight-or-flight response0302 clinical medicineEndocrinologyCONNECTIVITYAdaptation PsychologicalBRAINADAPTATIONReactivity (psychology)fMRIArea under the curvePrognosisNETWORKSPsychiatry and Mental healthAcute DiseaseFemaleStress reactivityAdultHypothalamo-Hypophyseal Systemmedicine.medical_specialtySALIVARYPSYCHOSOCIAL STRESSdACCHair cortisol concentrationContext (language use)Young Adult03 medical and health sciencesInternal medicinemedicineHumansEndocrine systemEXPOSUREAcute stressSalivaBiological PsychiatryDORSALResilienceEndocrine and Autonomic Systemsbusiness.industryAcute social stress030227 psychiatryEndocrinologyANTERIOR CINGULATE CORTEXImmunizationbusinessStress Psychological030217 neurology & neurosurgeryHairPsychoneuroendocrinology
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Diazepam has no beneficial effects on stress-induced behavioural and endocrine changes in male tree shrews.

2000

Abstract VAN KAMPEN, M., U. SCHMITT, C. HIEMKE AND E. FUCHS. Diazepam has no beneficial effects on stress-induced behavioural and endocrine changes in male tree shrews. PHARMACOL BIOCHEM BEHAV 65 (3) 539–546, 2000.—The present study evaluated the effect of subchronic oral treatment of psychosocially stressed male tree shrews with diazepam on locomotor activity, marking behavior, avoidance behavior, and urinary cortisol and noradrenaline. To mimic a realistic situation of anxiolytic intervention, the treatment started 14 days after the beginning of psychosocial stress; at that time, the stress-induced behavioral and endocrine alterations had been established. The drug (5 mg/kg/day) was admin…

MaleClomipraminemedicine.medical_specialtyHypothalamo-Hypophyseal Systemmedicine.drug_classClinical BiochemistryTricyclic antidepressantPituitary-Adrenal SystemMotor ActivityToxicologyBiochemistryAnxiolyticBehavioral NeuroscienceInternal medicinemedicineAvoidance LearningEndocrine systemAnimalsBiological PsychiatryHydrocortisonePharmacologyDiazepamBehavior AnimalTemazepamBody WeightTupaiidaeEndocrinologyOxazepamAnti-Anxiety AgentsPsychologyDiazepamStress Psychologicalmedicine.drugPharmacology, biochemistry, and behavior
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Diurnal cortisol secretion and health-related quality of life in healthy older people

2021

Abstract Several studies have demonstrated that a dysregulated hypothalamic-pituitary-adrenal (HPA) axis is related to worse health status (e.g., depression, posttraumatic stress, or diabetes, among others). However, less is known about the association between the individual's perception of their own health status and HPA-axis functioning in healthy older people. The aim of the present study was to examine the relationship between HPA-axis functioning and health-related quality of life (HRQoL) in healthy older people. To do this, 140 healthy older people (69 men and 71 women) from 56 to 76 years old collected eight saliva samples on two consecutive weekdays to measure the diurnal cortisol c…

MaleCortisol secretionHypothalamo-Hypophyseal Systemendocrine systemCortisol awakening responseHydrocortisoneHealth StatusPituitary-Adrenal SystemBedtime050105 experimental psychology03 medical and health sciences0302 clinical medicineQuality of lifePhysiology (medical)Diabetes mellitusHumansMedicine0501 psychology and cognitive sciencesSalivaDepression (differential diagnoses)Agedbusiness.industryGeneral Neuroscience05 social sciencesMiddle Agedmedicine.diseaseMental healthCircadian RhythmNeuropsychology and Physiological PsychologyQuality of LifeFemalebusinessOlder peoplehormones hormone substitutes and hormone antagonists030217 neurology & neurosurgeryClinical psychologyInternational Journal of Psychophysiology
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