6533b82efe1ef96bd1292a3b
RESEARCH PRODUCT
Epiphany root canal sealer prepared with resinous solvent is irritating to rat subcutaneous tissues.
Manoel Damião Sousa-netoÉLcio DaleffeJosé E. Vieira-ozórioDanyel E. Da-cruz-perezsubject
MaleBiocompatibilityAdult maleRoot canalmedia_common.quotation_subjectDentistryEndodonticsRoot Canal Filling MaterialsSubcutaneous TissueMaterials TestingmedicineAnimalsRats WistarGeneral Dentistrymedia_commonInflammationChemistrybusiness.industryChronic inflammatory reaction:CIENCIAS MÉDICAS [UNESCO]Epiphany sealerRatsSolventResins Syntheticmedicine.anatomical_structureOtorhinolaryngologyEpiphanyUNESCO::CIENCIAS MÉDICASSolventsSurgeryResearch-ArticlebusinessSubcutaneous tissuedescription
Objective: This study assessed the biocompatibility of the Epiphany endodontic sealer prepared with resinous solvent of Epiphany system (Thinning resin) in rat subcutaneous tissues. Study Design: Polyethylene tubes were filled with the sealer and 4 groups were established: GI, Epiphany prepared with 1 drop of resinous solvent (RS); GII, Epiphany prepared with 1 drop of RS and photoactivated; GIII, Epiphany associated with self-etch primer and prepared with 1 drop of RS; GIV, Epiphany associated with self-etch primer, prepared with 1 drop of RS and photoactivated. The filled tubes were implanted into 4 different regions of the dorsum of 20 adult male rats. Results: After 7, 14 and 21 days, all groups presented a moderate to severe chronic inflammation, necrosis and foreign-body giant cells. At 42 days, although the intensity of chronic inflammatory reaction decreased, the other features still were observed. Conclusion: The Epiphany sealer prepared with the RS was irritating to rat subcutaneous tissues. Key words:Biocompatibility, Epiphany, methacrylate resin sealer, resinous solvent, root canal sealer.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-07-05 | Medicina oral, patologia oral y cirugia bucal |