Search results for "selection"
showing 10 items of 1940 documents
Comparison of classification methods that combine clinical data and high-dimensional mass spectrometry data
2013
Background The identification of new diagnostic or prognostic biomarkers is one of the main aims of clinical cancer research. Technologies like mass spectrometry are commonly being used in proteomic research. Mass spectrometry signals show the proteomic profiles of the individuals under study at a given time. These profiles correspond to the recording of a large number of proteins, much larger than the number of individuals. These variables come in addition to or to complete classical clinical variables. The objective of this study is to evaluate and compare the predictive ability of new and existing models combining mass spectrometry data and classical clinical variables. This study was co…
Familiarization process in cardiorespiratory fitness testing for persons with mental retardation
1995
The purpose of this article is to review the familiarization protocols and other factors used in laboratory and field testing studies implemented to measure the cardiorespiratory fitness of persons with mental retardation. Test selection issues, pretest familiarization procedures, and motivational strategies will be discussed. Little information is available to identify specific guidelines for familiarizing a subject with a specific protocol prior to cardiorespiratory fitness testing. The recommendations suggested in this article provide valuable and necessary information for researchers interested in the measurement of cardiorespiratory fitness of persons with mental retardation.
Educational Experiments: Childhood Sympathy, Regulation, and Object-Relations in Maria Edgeworth’s Writings About Education
2020
Charles Armstrong takes as his subject the place of infancy in Romantic-period ideas about education, with particular focus on the educational fiction of Maria Edgeworth, one of the most influential writers for children of the day. Armstrong contextualizes a selection of Edgeworth’s fiction for children in relation to the pedagogic treatise Practical Education (1798) which she co-authored with her father as well as a range of other contemporary debates about the role of literature in infant education. Armstrong reads Edgeworth’s writing for children as engaged in a complex dialogue both with earlier, Enlightenment ideas and with emergent, Romantic paradigms. In so doing, he not only sheds n…
What is psychotherapy today? Overview of psychotherapeutic concepts
2020
Pawlak Adam, Kacprzyk-Straszak Agnieszka. What is psychotherapy today? Overview of psychotherapeutic concepts. Journal of Education, Health and Sport. 2020;10(5):19-32. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2020.10.05.002 https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2020.10.05.002 https://zenodo.org/record/3784514 The journal has had 5 points in Ministry of Science and Higher Education parametric evaluation. § 8. 2) and § 12. 1. 2) 22.02.2019. © The Authors 2020; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distribute…
German registry for acute aortic dissection type A (GERAADA)--lessons learned from the registry.
2010
A German registry for acute aortic dissection type A (GERAADA) was initiated by the Working Group for Aortic Surgery and Interventional Vascular Surgery of the German Society for Thoracic and Cardiovascular Surgery (GSTCVS) in July 2006. This web-based database was developed to record the data of patients who had undergone surgery for aortic dissection type A. From analyzing the data, we aim to learn how to improve surgical treatment and to identify parameters affecting patient outcome. In the beginning, 33 cardiac centers participated via online access to the registry on the GSTCVS' homepage. Since then, 43 centers in Germany, Switzerland and Austria have begun entering data on the pre- an…
Prognostic scoring system predictive of survival after surgical resection of esophageal carcinoma.
2013
BACKGROUND The aim of our study was to develop a prognostic index score for patients undergoing surgical resection for esophageal cancer that accurately determines survival with specific clinicopathological characteristics. METHODS Clinical, histological, and demographical variables of 475 patients were entered in an univariate and multivariate regression model, followed by individual calculation of the Prognostic Indicator Score and model validation via simulation. RESULTS Significant variables included in the scoring system were number of positive lymph nodes, pT, pL, R, obesity, and American Society of Anesthesiologist classification. Survival probability and its associated hazard functi…
Improved identification of thrombolysis candidates amongst intermediate-risk pulmonary embolism patients: implications for future trials.
2017
Defining a “higher-risk” population among intermediate-risk patients with pulmonary embolism included in PEITHO http://ow.ly/JM7u30hcSgN
ISHLT consensus document on lung transplantation in patients with connective tissue disease: Part I: Epidemiology, assessment of extrapulmonary condi…
2021
Patients with connective tissue disease (CTD) and advanced lung disease are often considered suboptimal candidates for lung transplantation (LTx) due to their underlying medical complexity and potential surgical risk. There is substantial variability across LTx centers regarding the evaluation and listing of these patients. The International Society for Heart and Lung Transplantation-supported consensus document on lung transplantation in patients with CTD standardization aims to clarify definitions of each disease state included under the term CTD, to describe the extrapulmonary manifestations of each disease requiring consideration before transplantation, and to outline the absolute contr…
Eligibility of real-life patients with copd for inclusion in rcts: A commentary
2017
Randomized clinical trials (RCTs) are performed to provide evidence to support treatment decisions. Based on the nature of those studies and the need to avoid confounding factors, it has been argued that the population selected in RCTs only partially represents the real-life population. This assumption casts doubts on the applicability of the results provided by RCTs in the management of individuals with an established diagnosis of COPD, and advocates the need for complementary studies with a pragmatic design. Herein, we comment on the recent article published by Halpin and colleagues on the Journal [Halpin et al, Respir Res 17:120, 2016], in which higher rates of inclusions in RCTs for COP…
Eligibility for treatment with omalizumab in Italy and Germany.
2013
Summary Omalizumab is an add-on therapy for patients with uncontrolled severe allergic asthma. In Europe, patients must fulfil a number of additional criteria to become eligible for omalizumab therapy, creating a challenge for epidemiology studies to quantify the potential patient pool. Thus, and in the absence of robust data, the number of omalizumab-eligible patients has remained unclear. To assess eligible patient numbers, a chart-audit design approach was employed to measure epidemiology variables based on patient-level data. 770 patient charts were reviewed in designated towns in Germany and Italy, in collaboration with >200 primary care physicians (PCPs) and respiratory specialists (R…