Search results for "sensi"

showing 10 items of 5553 documents

Multi-mycotoxin analysis in wheat semolina using an acetonitrile-based extraction procedure and gas chromatography–tandem mass spectrometry

2012

A new analytical method for the rapid and simultaneous determination of ten mycotoxins including patulin, zearalenone and eight trichothecenes (nivalenol, fusarenon-X, diacetoxyscirpenol, 3-acetyl-deoxynivalenol, neosolaniol, deoxynivalenol, T-2 and HT-2) in wheat semolina has been developed and optimized. Sample extraction and purification were performed with a modified QuEChERS-based (acronym of Quick, Easy, Cheap, Effective, Rugged and Safe) procedure and determined by gas chromatography (GC) coupled to triple quadrupole instrument (QqQ). This is the first paper on the application of GC-QqQ-MS/MS to analysis of mycotoxins. Careful optimization of the gas chromatography-tandem mass spectr…

AcetonitrilesChromatographyGas Chromatography/Tandem Mass SpectrometryCalibration curveFlourLiquid-Liquid ExtractionOrganic ChemistryAnalytical chemistryReproducibility of ResultsGeneral MedicineHydrogen-Ion ConcentrationMycotoxinsQuechersSensitivity and SpecificityBiochemistryGas Chromatography-Mass SpectrometryDiacetoxyscirpenolAnalytical ChemistryTriple quadrupole mass spectrometerPatulinchemistry.chemical_compoundchemistryTandem Mass SpectrometryGas chromatographyGas chromatography–mass spectrometryJournal of Chromatography A
researchProduct

Optimised procedures for the reversed-phase liquid chromatographic analysis of formulations containing tricyclic antidepressants.

2003

The chromatographic behaviour (retention, selectivity, peak shape and resolution) of seven tricyclic antidepressants (TCAs), amitryptiline, clomipramine, doxepin, imipramine, maprotiline, nortryptiline and trimipramine, was examined. Conventional unendcapped Cs and C18 columns and an endcapped XTerra MS C18 column recommended for the analysis of basic compounds were used together with acetonitrile-water and micellar sodium dodecylsulfate (SDS)-pentanol mobile phases. The two best combinations were XTerra C18/acetonitrile, which yielded the largest efficiencies and resolution, and C8/SDS-pentanol, which eliminated the peak tails that were still observed with the XTerra C18 column. Both the s…

AcetonitrilesResolution (mass spectrometry)Clinical BiochemistryPharmaceutical ScienceCapsulesAntidepressive Agents TricyclicSensitivity and SpecificityDosage formAnalytical Chemistrychemistry.chemical_compoundDrug DiscoverymedicineAcetonitrileSpectroscopyChromatography High Pressure LiquidChromatographyExtraction (chemistry)Reproducibility of ResultsReversed-phase chromatographyDoxepinTrimipraminechemistry1-PentanolSolventsmedicine.drugTabletsJournal of pharmaceutical and biomedical analysis
researchProduct

Impact of biotic interactions on the survival of emerging pathogen Acinetobacter baumannii in aquatic media

2019

Abstract Acinetobacter baumannii is an opportunistic pathogen causing infections in immunocompromised patients. Recent studies recorded its persistence in a variety of abiotic conditions, but data regarding the biotic interactions with other microorganisms are limited. The aim was to assess the interaction of clinically relevant A. baumannii with common faecal bacteria Escherichia coli and Enterococcus faecium. Additionally, the interaction with a bdelloid rotifer Adineta vaga as a potential agent for biological control of A. baumannii was examined. Experiments were conducted in nutrient-poor spring water (SW) and nutrient-rich diluted nutrient broth (DNB) at 22 °C. A. baumannii coexisted w…

Acinetobacter baumanniiEnvironmental Engineeringmedicine.drug_classMicroorganismAntibioticsRotiferHuman pathogenMicrobial Sensitivity TestsWastewatermedicine.disease_causeMicrobiology03 medical and health sciencesmedicineEscherichia coliHumansEscherichia coliAcinetobacter baumannii ; bacteria ; inter-bacterial interaction ; rotifers030304 developmental biologyWater Science and Technology0303 health sciencesbiology030306 microbiologybiochemical phenomena metabolism and nutritionbiology.organism_classificationbacterial infections and mycoses6. Clean waterAcinetobacter baumanniiAnti-Bacterial AgentsbacteriaBacteriaEnterococcus faecium
researchProduct

Drug resistance patterns of bacteria isolated from patients with nosocomial pneumonia at Tehran hospitals during 2009-2011

2013

Introduction: Nosocomial pneumonia remains an important cause of mortality and morbidity worldwide. Surveillance programs play an important role in the identification of common etiologic agents and local patterns of antimicrobial resistance. Methodology: In this study we determined the frequency and antimicrobial susceptibility of pathogens isolated from patients with nosocomial pneumonia during 2009 to 2011. Results: A total of 642 bacteria were isolated from 516 suspected samples. Acinetobacter baumannii (21.1%, n = 136), was the commonest isolated pathogen followed by Pseudomonas aeruginosa (17.4%, n = 112) , Staphylococcus aureus (15.8%, n = 102) and enterococci (8.4% n = 54). The most …

Acinetobacter baumanniiSettore MED/07 - Microbiologia E Microbiologia ClinicaPenicillanic AcidDrug resistanceIranmedicine.disease_causechemistry.chemical_compoundLevofloxacinDrug Resistance Multiple BacterialPrevalenceRespiratory Tract InfectionsPolymyxin BCross InfectionbiologyCeftriaxoneGeneral MedicineHospitalsAcinetobacter baumanniiAnti-Bacterial AgentsInfectious DiseasesPiperacillin Tazobactam Drug CombinationPseudomonas aeruginosaCeftriaxonemedicine.drugMethicillin-Resistant Staphylococcus aureusStaphylococcus aureusMicrobial Sensitivity TestsMicrobiologyTazobactamMicrobiologyAntibiotic resistanceAcinetobacter baumanniiiVirologymedicinePneumonia BacterialHumansTehran hospitalsGram-Positive Bacterial InfectionsPiperacillindrug resistancebusiness.industryPseudomonas aeruginosanosocomial pneumoniaSputumbiochemical phenomena metabolism and nutritionbacterial infections and mycosesbiology.organism_classificationchemistrynosocomial pneumonia; drug resistance; Acinetobacter baumanniii; Pseudomonas aeruginosa; Tehran hospitalsLinezolidParasitologybusinessGram-Negative Bacterial Infections
researchProduct

Cladosins L-O, new hybrid polyketides from the endophytic fungus Cladosporium sphaerospermum WBS017

2019

Abstract The endophytic fungus Cladosporium sphaerospermum WBS017 was obtained from healthy bulbs of Fritillaria unibracteata var. wabuensis. Fermentation of C. sphaerospermum on solid rice medium yielded three new hybrid polyketides, cladosins L−N (1–3), and a known derivative cladodionen (4). Further cultivation of this fungus on white bean medium afforded an additional new hybrid polyketide, cladosin O (5) along with three known analogues (6–8). The structures of the new compounds were elucidated using a combination of NMR and HRESIMS data. The absolute configurations of compounds 2 and 3 were determined by Mosher’s method and TDDFT-ECD calculations. All isolated compounds were evaluated…

Acinetobacter baumanniiStaphylococcus aureusAntifungal AgentsUstilagoStereochemistryAntineoplastic AgentsMicrobial Sensitivity TestsSaccharomyces cerevisiaeFungusmedicine.disease_cause01 natural sciencesMiceStructure-Activity Relationship03 medical and health sciencesPolyketideCell Line TumorDrug DiscoveryEnterococcus faecalisUstilagomedicineAnimalsDensity Functional TheoryCell Proliferation030304 developmental biologyPharmacology0303 health sciencesDose-Response Relationship DrugMolecular Structurebiology010405 organic chemistryChemistryOrganic ChemistryFritillaria unibracteataMycobacterium tuberculosisGeneral Medicinebiology.organism_classificationAntimicrobialAnti-Bacterial Agents0104 chemical sciencesStaphylococcus aureusPolyketidesPseudomonas aeruginosaFermentationDrug Screening Assays AntitumorAntibacterial activityCladosporiumEuropean Journal of Medicinal Chemistry
researchProduct

High susceptibility of MDR and XDR Gram-negative pathogens to biphenyl-diacetylene-based difluoromethyl-allo-threonyl-hydroxamate LpxC inhibitors

2016

International audience; Inhibitors of uridine diphosphate-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC, which catalyses the first, irreversible step in lipid A biosynthesis) are a promising new class of antibiotics against Gram-negative bacteria. The objectives of the present study were to: (i) compare the antibiotic activities of three LpxC inhibitors (LPC-058, LPC-011 and LPC-087) and the reference inhibitor CHIR-090 against Gram-negative bacilli (including MDR and XDR isolates); and (ii) investigate the effect of combining these inhibitors with conventional antibiotics.MethodsMICs were determined for 369 clinical isolates (234 Enterobacteriaceae and 135 non-fermentati…

Acinetobacter baumanniiThreonine0301 basic medicineMicrobiology (medical)Klebsiella pneumoniaemedicine.drug_class030106 microbiologyAntibioticsMicrobial Sensitivity TestsHydroxamic Acidsmedicine.disease_causebeta-LactamasesAmidohydrolasesMicrobiology03 medical and health sciencesBacterial ProteinsEnterobacteriaceae[ SDV.MP ] Life Sciences [q-bio]/Microbiology and ParasitologyDrug Resistance Multiple BacterialGram-Negative BacteriaEscherichia colipolycyclic compoundsmedicineHumansPharmacology (medical)Enzyme InhibitorsOriginal ResearchPharmacologybiologyPseudomonas aeruginosaEnterobacteriaceae Infectionsbiochemical phenomena metabolism and nutritionbacterial infections and mycosesAntimicrobialbiology.organism_classificationEnterobacteriaceaeAnti-Bacterial Agents3. Good healthAcinetobacter baumanniiCiprofloxacinKlebsiella pneumoniae[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyInfectious DiseasesAmikacinPseudomonas aeruginosalipids (amino acids peptides and proteins)medicine.drugJournal of Antimicrobial Chemotherapy
researchProduct

Dissemination of a Carbapenem-Resistant Acinetobacter baumannii Strain Belonging to International Clone II/Sequence Type 2 and Harboring a Novel AbaR…

2013

ABSTRACT An outbreak of hospital-acquired Acinetobacter baumannii infections, caused by a bla OXA-23 -positive carbapenem-resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and the intI1-aacA4-catB8-aadA1-qacE Δ 1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼46,500 bp containing structures similar to the previously described AbaR22 and Tn 6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn 6022a interrupted by Tn 2006 carrying the bla OXA-23 gene.

Acinetobacter baumanniiclone (Java method)Genomic IslandsMolecular Sequence DataMicrobial Sensitivity TestsIntegronbeta-Lactam Resistancebeta-LactamasesDisease OutbreaksIntegronsMicrobiologyMechanisms of ResistancePharmacology (medical)GeneVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical molecular biology: 711Sequence (medicine)PharmacologyCross InfectionMolecular EpidemiologyMolecular epidemiologyStrain (chemistry)biologyOutbreakMethyltransferasesVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical microbiology: 715biology.organism_classificationLatviaAnti-Bacterial AgentsBacterial Typing TechniquesAcinetobacter baumanniiInfectious DiseasesCarbapenemsVDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk immunologi: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk mikrobiologi: 715DNA Transposable Elementsbiology.proteinGenes MDRVDP::Medical disciplines: 700::Basic medical dental and veterinary science disciplines: 710::Medical immunology: 716VDP::Medisinske Fag: 700::Basale medisinske odontologiske og veterinærmedisinske fag: 710::Medisinsk molekylærbiologi: 711Acinetobacter Infections
researchProduct

Mapping landscape canopy nitrogen content from space using PRISMA data

2021

Abstract Satellite imaging spectroscopy for terrestrial applications is reaching maturity with recently launched and upcoming science-driven missions, e.g. PRecursore IperSpettrale della Missione Applicativa (PRISMA) and Environmental Mapping and Analysis Program (EnMAP), respectively. Moreover, the high-priority mission candidate Copernicus Hyperspectral Imaging Mission for the Environment (CHIME) is expected to globally provide routine hyperspectral observations to support new and enhanced services for, among others, sustainable agricultural and biodiversity management. Thanks to the provision of contiguous visible-to-shortwave infrared spectral data, hyperspectral missions open enhanced …

Active learningActive learning (machine learning)Computer scienceDimensionality reductionHyperspectral imagingPRISMAContext (language use)CollinearityHybrid retrievalDimensionality reductionImaging spectroscopyAtomic and Molecular Physics and OpticsComputer Science ApplicationsImaging spectroscopyCHIMEKrigingEnMAPCanopy nitrogen contentComputers in Earth SciencesEngineering (miscellaneous)Gaussian process regressionRemote sensingISPRS Journal of Photogrammetry and Remote Sensing
researchProduct

Remote sensing image segmentation by active queries

2012

Active learning deals with developing methods that select examples that may express data characteristics in a compact way. For remote sensing image segmentation, the selected samples are the most informative pixels in the image so that classifiers trained with reduced active datasets become faster and more robust. Strategies for intelligent sampling have been proposed with model-based heuristics aiming at the search of the most informative pixels to optimize model's performance. Unlike standard methods that concentrate on model optimization, here we propose a method inspired in the cluster assumption that holds in most of the remote sensing data. Starting from a complete hierarchical descri…

Active learningComputer scienceActive learning (machine learning)SvmMultispectral image0211 other engineering and technologies02 engineering and technologyMultispectral imageryClusteringMultispectral pattern recognitionArtificial Intelligence0202 electrical engineering electronic engineering information engineeringSegmentationCluster analysis021101 geological & geomatics engineeringRetrievalPixelbusiness.industryLinkageHyperspectral imagingPattern recognitionRemote sensingSupport vector machineMultiscale image segmentationHyperspectral imageryPixel ClassificationSignal Processing020201 artificial intelligence & image processingHyperspectral Data ClassificationComputer Vision and Pattern RecognitionArtificial intelligencebusinessAlgorithmsSoftwareModel
researchProduct

Discovering single classes in remote sensing images with active learning

2012

When dealing with supervised target detection, the acquisition of labeled samples is one of the most critical phases: the samples must be yet representative of the class of interest, but must also be found among a vast majority of non-target examples. Moreover, the efficiency of the search is also an issue, since the samples labeled as background are not used by target detectors such as the support vector data description (SVDD). In this work we propose a competitive and effective approach to identify the most relevant training samples for one-class classification based on the use of an active learning strategy. The SVDD classifier is first trained with insufficient target examples. It is t…

Active learningComputer scienceActive learning (machine learning)business.industryPattern recognitionSemi-supervised learningRemote sensingMachine learningcomputer.software_genreSupport vector machineActive learningLife ScienceSupport Vector Data DescriptionArtificial intelligencebusinessClassifier (UML)computerChange detection2012 IEEE International Geoscience and Remote Sensing Symposium
researchProduct