Search results for "sensor"

showing 10 items of 4594 documents

Persistent skin ulcers, mutilations, and acro-osteolysis in hereditary sensory and autonomic neuropathy with phospholipid excretion

1989

We observed three children in a Turkish family who from early childhood had deformations of the feet and torpid ulcers with subfocal osteomyelitis and osteolysis, which subsequently led to amputations. The fingers showed ainhumlike constriction bands and spontaneous amputations. Neurologic studies revealed an almost complete sensory and autonomic loss affecting all modalities and a marked involvement of motor fibers. The clinical symptoms fulfill many of the hallmarks of hereditary sensory and autonomic neuropathy type II, including autosomal recessive inheritance, onset of symptoms in childhood, and mutilating acropathy. A high urinary excretion of sphingomyelin and lecithin suggests that …

medicine.medical_specialtyOsteolysisbusiness.industryOsteomyelitisSensory systemDermatologymedicine.diseaseDermatologyAcro-OsteolysisExcretionEndocrinologyDegenerative diseaseInternal medicineHereditary sensory and autonomic neuropathymedicinebusinessPolyneuropathyJournal of the American Academy of Dermatology
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Changes on blood filterability in patients with fluctuant hearing loss

2006

Abstract We conducted a two-year follow-up of thirteen subjects with fluctuating sensorineural hearing loss, measuring their blood filterability (BF) and correlating it to the onset of episodes of deafness. We observed a decrease in the BF levels of all the patients when they experienced hearing loss. When the patients recovered their normal level of hearing, the BF also increased. The use of reactive techniques to avoid these decreases in BF could potentially prevent or correct fluctuating deafness.

medicine.medical_specialtyOtorhinolaryngologybusiness.industryHearing lossotorhinolaryngologic diseasesMedicineSensorineural hearing lossNormal levelIn patientAudiologymedicine.symptombusinessmedicine.diseaseActa Otorrinolaringológica Española
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Somatosensory amplification in hypochondriasis and panic disorder

1999

The aim of this study is to explore the differences and similarities of Somatic Amplification (SA) in both panic and hypochondriasis disorders. An additional objective is to validate the Somatosensory Amplification Scale (SSAS) for use in our cultural context. For these purposes, 34 patients (17 with hypochondriasis and 17 with panic disorder; DSM-III-R criteria) completed the following questionnaires: SSAS, State–Trait Anxiety Inventory, Beck Depression Inventory, MMPI Hypochondriasis Scale, Illness Attitude Scales and Illness Behaviour Questionnaire. The SSAS showed a satisfactory internal consistency (Cronbach's α=0·83), and revealed two components: ‘Internal Stimulus Amplification’ and …

medicine.medical_specialtyPanic disorderSomatosensory amplificationBeck Depression InventoryPanicmedicine.diseasebehavioral disciplines and activitieshumanitiesClinical PsychologyMinnesota Multiphasic Personality InventoryCronbach's alphaInternal consistencymedicineAnxietymedicine.symptomPsychologyPsychiatryClinical psychologyClinical Psychology & Psychotherapy
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Advanced technologies for detecting tremor in Parkinson's disease.

2019

Objective Accurate and reliable detection of tremor onset in Parkinson’s disease (PD) is critical to the success of adaptive deep brain stimulation (aDBS) therapy. Here, we investigated the potential use of feature engineering and machine learning methods for more accurate detection of rest tremor in PD. Methods We analyzed the local field potential (LFP) recordings from the subthalamic nucleus region in 12 patients with PD (16 recordings). To explore the optimal biomarkers and the best performing classifier, the performance of state-of-the-art machine learning (ML) algorithms and various features of the subthalamic LFPs were compared. We further used a Kalman filtering technique in feature…

medicine.medical_specialtyParkinson's diseaseEssential TremorRestMEDLINEAdaptive deep-brain stimulationArticlePhysical medicine and rehabilitationPhysiology (medical)TremormedicineHumansRest (music)Essential tremorbusiness.industryParkinson DiseaseMachine learning (ML)medicine.diseaseParkinson’s disease (PD)Sensory SystemsTremor detectionNeurologyLocal field potential (LFP)Neurology (clinical)businessKalman filteringClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Nonlinear irregularities in Parkinson's disease tremor and essential tremor.

2021

medicine.medical_specialtyParkinson's diseaseEssential tremorbusiness.industryEssential TremorParkinson Diseasemedicine.diseaseSensory SystemsPhysical medicine and rehabilitationNeurologyPhysiology (medical)TremormedicineHumansNeurology (clinical)businessClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
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Ambulatory Treatment and Telemonitoring of Patients with Parkinson’s Disease

2011

Body sensor networks (BSN) promise to enhance quality of life in common human habitats. The very next and natural step towards the improvement of the already valuable applications based on BSN is the incorporation of body actuator devices which adapt its actuation dynamically based on the information provided by the body sensors, thus forming Body Sensor and actuator Networks (BS&AN). This paper shows how BS&AN can be exploited to create an innovative system to support the treatment of patients affected by Parkinson’s Disease (PD). The combination of clinical and technological knowledge in BS&AN allows to significantly improve the quality of life of patients suffering from PD.

medicine.medical_specialtyParkinson's diseasebusiness.industrymedicine.diseasePhysical medicine and rehabilitationQuality of lifeSettore CHIM/09 - Farmaceutico Tecnologico ApplicativoAmbulatoryIntraoral deviceParkinson’s disease body sensor and actuator networks intraoral device HELP project mobile health mHealth.MedicineBody sensorsbusinessmHealthWireless sensor network
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Oxygen and glucose deprivation induces major dysfunction in the somatosensory cortex of the newborn rat

2005

The mechanisms and functional consequences of ischemia-induced injury during perinatal development are poorly understood. Subplate neurons (SPn) play a central role in early cortical development and a pathophysiological impairment of these neurons may have long-term detrimental effects on cortical function. The acute and long-term consequences of combined oxygen and glucose deprivation (OGD) were investigated in SPn and compared with OGD-induced dysfunction of immature layer V pyramidal cortical neurons (PCn) in somatosensory cortical slices from postnatal day (P)0-4 rats. OGD for 50 min followed by a 10-24-h period of normal oxygenation and glucose supply in vitro or in culture led to pron…

medicine.medical_specialtyPatch-Clamp TechniquesTolbutamideIn Vitro TechniquesBiologySomatosensory systemMembrane PotentialsInternal medicineSubplatemedicineExtracellularAnimalsHypoglycemic AgentsMagnesiumEnzyme InhibitorsHypoxiaOuabainNeuronsMembrane potentialCaspase 3General NeuroscienceDose-Response Relationship RadiationDepolarizationSomatosensory CortexHyperpolarization (biology)ImmunohistochemistryElectric StimulationRatsGlucoseNeuroprotective AgentsEndocrinologymedicine.anatomical_structureAnimals Newbornnervous systemApoptosisCaspasesNMDA receptorDizocilpine MaleateEuropean Journal of Neuroscience
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Overexpression of nerve growth factor in peritoneal fluid from women with endometriosis may promote neurite outgrowth in endometriotic lesions

2011

To investigate the role of the nerve growth factor (NGF) in the endometriosis-associated innervation in the development of endometriosis- associated symptoms, 41 peritoneal fluid samples (PF) from patients with surgically and histologically proven endometriosis and 20 PF from patients with other gynecologic conditions were analyzed with Western blot and a novel in vitro model using dorsal root ganglia (DRG) to show neuronal outgrowth; endometrial cells also were analyzed. The results suggest that the PF of endometriosis patients and endometriotic lesions have neurotropic properties, because the Western blot analysis and the cell culture stainings showed NGF expression, and the neurite outgr…

medicine.medical_specialtyPathologySensory Receptor CellsNeuriteBlotting WesternEndometriosisEndometriosisFluorescent Antibody TechniqueNerve fiberNeuriteChick Embryosensory nerve fiberPelvic PainEndometriumSensory Receptor Cellsensory nerveEndometriumpain conductionDysmenorrheaWestern blotGanglia SpinalNerve Growth FactorNeuritesmedicineAnimalsAscitic FluidHumansEndometriosiCells Culturedpathophysiology of endometriosis-related painGynecologymedicine.diagnostic_testAnimalbusiness.industryPeritoneal fluidObstetrics and Gynecologymedicine.diseaseEndometriosis; pain conduction; sensory nervemedicine.anatomical_structureNerve growth factornervous systemReproductive MedicineFemalebusinessHumanSensory nerveFertility and Sterility
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The Secretion of Areolar (Montgomery's) Glands from Lactating Women Elicits Selective, Unconditional Responses in Neonates

2009

Background The communicative meaning of human areolae for newborn infants was examined here in directly exposing 3-day old neonates to the secretion from the areolar glands of Montgomery donated by non related, non familiar lactating women. Methodology/Principal Findings The effect of the areolar stimulus on the infants' behavior and autonomic nervous system was compared to that of seven reference stimuli originating either from human or non human mammalian sources, or from an arbitrarily-chosen artificial odorant. The odor of the native areolar secretion intensified more than all other stimuli the infants' inspiratory activity and appetitive oral responses. These responses appeared to deve…

medicine.medical_specialtyPediatrics and Child Healthlcsh:MedicineDermatologyBreast milkStimulus (physiology)Autonomic Nervous SystemAreolar glandsObstetrics/Postpartum CareRespiratory RateHeart RateInternal medicineLactationmedicineHumansLactationSecretionBreastMental Health/Developmental and Pediatric Neurologylcsh:SciencePhysiology/Sensory SystemsEvolutionary Biology/Animal BehaviorNeuroscience/Behavioral NeuroscienceMultidisciplinaryMilk Humanbusiness.industryNeuroscience/Sensory Systemslcsh:RInfant NewbornSmellObstetrics/Breast FeedingOtolaryngology/RhinologyNeuroscience/PsychologyAutonomic nervous systemmedicine.anatomical_structureEndocrinologyMilk BanksOdorNipplesSucking BehaviorInfant BehaviorOdorantsFemalelcsh:QPediatrics and Child Health/NeonatologybusinessBreast feedingResearch ArticlePLoS ONE
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S2.2 Assessment of neuropathic pain. I. Psychophysical methods

2006

medicine.medical_specialtyPhysical medicine and rehabilitationNeurologybusiness.industryPhysiology (medical)Neuropathic painPsychophysicsMedicineNeurology (clinical)businessSensory SystemsClinical Neurophysiology
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