Search results for "sequence"
showing 10 items of 4987 documents
Development of Counting Skills: Role of Spontaneous Focusing on Numerosity and Subitizing-Based Enumeration
2007
Children differ in how much they spontaneously pay attention to quantitative aspects of their natural environment. We studied how this spontaneous tendency to focus on numerosity (SFON) is related to subitizing-based enumeration and verbal and object counting skills. In this exploratory study, children were tested individually at the age of 4–5 years on these skills. Results showed 2 primary relationships in children's number skills development. Performance in a number sequence production task, which is closely related to ordinal number sequence without reference to cardinality, is directly associated with SFON. Second, the association of SFON and object counting skills, which require relat…
Biotechnological potential of respiring Zymomonas mobilis: a stoichiometric analysis of its central metabolism.
2013
The active, yet energetically inefficient electron transport chain of the ethanologenic bacterium Zymomonas mobilis could be used in metabolic engineering for redox-balancing purposes during synthesis of certain products. Although several reconstructions of Z. mobilis metabolism have been published, important aspects of redox balance and aerobic catabolism have not previously been considered. Here, annotated genome sequences and metabolic reconstructions have been combined with existing biochemical evidence to yield a medium-scale model of Z. mobilis central metabolism in the form of COBRA Toolbox model files for flux balance analysis (FBA). The stoichiometric analysis presented here sugges…
Recommended practice for out-of-hospital emergency anaesthesia in adults: Statement from the Out-of-Hospital Emergency Anaesthesia Working Group of t…
2016
Emergency anaesthesia is an important therapeutic measure in out-of-hospital emergency medicine. The associated risks are considerably higher than those of in-hospital anaesthesia. The primary objectives of emergency anaesthesia are hypnosis, analgesia, oxygenation and ventilation through airway management. The secondary objectives of emergency anaesthesia are amnesia, anxiolysis, the reduction of oxygen consumption and respiratory work, the protection of vital organs and the avoidance of secondary myocardial and cerebral damage. A critical evaluation of the indications for outof- hospital emergency anaesthesia must take into consideration patient, case and provider-related factors. Rapid s…
Topological classification of 4-dimensional complete intersections
1996
Let X,,(d) C C P "+r denote a complete intersection, the transversal intersection of r hypersurfaces in C P ~+r defined by r homogeneous polynomials of degrees (d l , . . . ,dr) =: d, with dld2...d,. =: d the total degree. It is well-known that the diffeomorphism type of X,,(d) is determined by n and d. In [7] and [8], Libgober and Wood showed that in dimension n -~ 2, there exist k distinct multidegrees ibr any integer k 6 N such that the corresponding complete intersections are all diffeomorphic. For n = 1,3, the diffeomorphism classification of Xn(d) is well-known by surface theory and the classification of 1-connected six-manifolds [12] respectively. For 7z = 2, at least the topological…
Limit Periodic Sets
1998
As explained at the end of the previous chapter, the most difficult problem in the study of bifurcations in a family of vector fields on a surface of genus 0 is the control of the periodic orbits. In fact, in generic smooth families the periodic orbits will be isolated for each value of the parameter. For analytic families we have two possibilities for each orbit: it may be isolated or belong to a whole annulus of periodic orbits. In this last case and for the parameter values for which the system has infinitely many periodic orbits, the vector field has a local analytic first integral and the nearby vector fields in the family may be studied by the perturbation theory introduced in Chapter…
Reinforced Room-Temperature Spin Filtering in Chiral Paramagnetic Metallopeptides
2020
Chirality-induced spin selectivity (CISS), whereby helical molecules polarize the spin of electrical current, is an intriguing effect with potential applications in nanospintronics. In this nascent field, the study of the CISS effect using paramagnetic chiral molecules, which could introduce another degree of freedom in controlling the spin transport, remains so far unexplored. To address this challenge, herein we propose the use of self-assembled monolayers (SAMs) of helical lanthanide-binding peptides. To elucidate the effect of the paramagnetic nuclei, monolayers of the peptide coordinating paramagnetic or diamagnetic ions are prepared. By means of spin-dependent electrochemistry, the CI…
The ICT Implication on CSR in the Tourism of Emerging Markets
2012
Abstract Tourism has a significant environmental, social and human impact. No other sector provides jobs and ensures wealth across poor countries in the same way as tourism. In the context of sustainable responsible tourism, the concept of Corporate Social Responsibility CSR has gained increased importance: CSR is a company's understanding of the role it plays in society, the environment in which it operates, the values it upholds and its awareness of the intended and unintended consequences of its actions. ICT can create many environmental benefits and there have been several optimistic assessments of the overall relationship between e-business and sustainable development. ICT-based servic…
Determinants essential for the transmissible gastroenteritis virus-receptor interaction reside within a domain of aminopeptidase-N that is distinct f…
1994
The swine-specific coronavirus transmissible gastroenteritis virus (TGEV) uses pig aminopeptidase-N (pAPN) as a cellular receptor. We showed that the human aminopeptidase-N (hAPN) cannot substitute for pAPN in this respect, although the two enzymes have 80% amino acid sequence identity. In order to map the TGEV binding site on pAPN, we constructed a series of APN cDNA chimeras between pAPN and hAPN and analyzed them for their capacity to confer infectivity. The region between residues 717 and 813 was found to be essential for infectivity. This region also contains the epitopes for three TGEV-blocking monoclonal antibodies directed against pAPN. These data support the view that the catalytic…
Closing in on the toxic domain through analysis of a variant Clostridium difficile cytotoxin B
1995
Strain 1470 is the standard typing strain for serogroup F of Clostridium difficile containing both toxin genes, toxA-1470 and toxB-1470. A polymerase chain reaction (PCR)-based approach to the sequencing of the total toxB-1470 gene identified an open reading frame (ORF) of 7104 nucleotides. In comparison with the previously sequenced toxB of C. difficile VP10463, the toxB-1470 gene has 16 additional nucleotides, 13 within the 5'-untranslated region and three within the coding region. The M(r) of ToxB-1470 is 269,262, with an isoelectric point (IP) of 4.16. The equivalent values for ToxB are M(r) 269,709 and IP 4.13. In comparison with ToxB, ToxB-1470 differs primarily in the N-terminal regi…
Molecular study of porcine transmissible gastroenteritis virus after serial animal passages revealed point mutations in S protein
2010
Porcine respiratory coronavirus is related genetically to porcine transmissible gastroenteritis virus with a large deletion in S protein. The respiratory virus is a mutated form that may be a consequence of the gastroen- teritis virus's evolution. Intensive passages of the virus in its natural host may enhance the appearance of mutations and therefore may contribute to any attenuated form of the virus. The objective of this study was to characterize the porcine transmissible gastroenteritis virus TMK22 strain after passages in piglets from 1992 until 2007. A typical experimental infection, molecular characterization, and serological analysis were also carried out to further char- acterize a…