Search results for "sequences"
showing 10 items of 359 documents
How copper ions and membrane environment influence the structure of the human and chicken tandem repeats domain?
2019
Abstract Prion proteins (PrPs) from different species have the enormous ability to anchor copper ions. The N-terminal domain of human prion protein (hPrP) contains four tandem repeats of the –PHGGGWGQ– octapeptide sequence. This octarepeat domain can bind up to four Cu2+ ions. Similarly to hPrP, chicken prion protein (chPrP) is able to interact with Cu2+ through the tandem hexapeptide -HNPGYP- region (residues 53–94). In this work, we focused on the human octapeptide repeat (human Octa4, hPrP60–91) (Ac-PHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQ-NH2) and chicken hexapeptide repeat (chicken Hexa4, chPrP54–77) (Ac-HNPGYPHNPGYPHNPGYPHNPGYP-NH2) prion protein fragments. Due to the fact that PrP is a membr…
Balanced Words Having Simple Burrows-Wheeler Transform
2009
The investigation of the "clustering effect" of the Burrows-Wheeler transform (BWT) leads to study the words having simple BWT , i.e. words w over an ordered alphabet $A=\{a_1,a_2,\ldots,a_k\}$, with $a_1 < a_2 < \ldots <a_k$, such that $bwt(w)$ is of the form $a_k^{n_k} a_{k-1}^{n_{k-1}} \cdots a_1^{n_1}$, for some non-negative integers $n_1, n_2, \ldots, n_k$. We remark that, in the case of binary alphabets, there is an equivalence between words having simple BWT, the family of (circular) balanced words and the conjugates of standard words. In the case of alphabets of size greater than two, there is no more equivalence between these notions. As a main result of this paper we prove that, u…
Factors Behind Junk DNA in Bacteria
2012
Although bacterial genomes have been traditionally viewed as being very compact, with relatively low amounts of repetitive and non-coding DNA, this view has dramatically changed in recent years. The increase of available complete bacterial genomes has revealed that many species present abundant repetitive DNA (i.e., insertion sequences, prophages or paralogous genes) and that many of these sequences are not functional but can have evolutionary consequences as concerns the adaptation to specialized host-related ecological niches. Comparative genomics analyses with close relatives that live in non-specialized environments reveal the nature and fate of this bacterial junk DNA. In addition, the…
The invisible violence. The denial of relational trauma and its consequences in early childhood.
2016
Abstract The paper is aimed at the analysis of recognition and legitimacy problems, historically present in the study of psychological trauma, as well as to opening reflections on the possibility that these difficulties are still current. Recent contributions on the study of the developmental trauma disorder mainly highlight the importance of relational and cumulative aspects and during the developmental cycle when the subject experiences his/her traumatic events. Multiple exposures to interpersonal trauma in fact have a stronger impact on the first decade of life, resulting in predictable consequences on at least seven mental functioning areas. Several authors propose a new diagnostic labe…
Perdió el libro que se compró / había comprado pocos días antes: Reflexiones iniciales en torno al saber gramatical sobre los tiempos verbales del pa…
2007
Carmen.Rdez-Gonzalo@uv.es La alternancia entre los tiempos verbales del pasado en textos escritos exige tener en cuenta diferencias aspectuales poco presentes en el español hablado. Según López García (2005: 162), el sistema de cinco tiempos simples (vengo, venía, vine, vendría, vendré) cubre las necesidades expresivas de los hispanohablantes, aunque los niños emplean menos y muchos hablantes adultos raramente usan otras formas. Los problemas se plantean cuando en lugar de hablar español necesitamos escribirlo y leerlo. Esta necesidad cambia por completo el inventario de tiempos ya que, para articular un texto es preciso dejar muy claro que unos acontecimientos ocurren antes o después de ot…
Combined approach to atrial and ventricular function for assessment of diastole through MRI: Hypertrophic Cardiomyopathy (HCM) vs Healthy Controls (H…
2013
Purpose Methods and Materials Results Conclusion References Personal Information
Semi-natural habitats in the European boreal region: Caught in the socio-ecological extinction vortex?
2022
AbstractWe propose to consider semi-natural habitats—hotspots for biodiversity—being caught in a socio-ecological extinction vortex, similar to the phenomenon described for species threatened with extinction. These habitats are essentially socioecological systems, in which socioeconomic drivers are interlinked with ecological processes. We identify four highly interlinked and mutually reinforcing socio-economic processes, pertaining to the importance of semi-natural habitats for (i) agricultural production, (ii) policy, research and development; (iii) vocational education in the fields of agricultural sciences and (iv) public’s experiences with semi-natural habitats. Evidence from six count…
STR analysis of artificially degraded DNA--results of a collaborative European exercise.
2003
Degradation of human DNA extracted from forensic stains is, in most cases, the result of a natural process due to the exposure of the stain samples to the environment. Experiences with degraded DNA from casework samples show that every sample may exhibit different properties in this respect, and that it is difficult to systematically assess the performance of routinely used typing systems for the analysis of degraded DNA samples. Using a batch of artificially degraded DNA with an average fragment size of approx. 200 bp a collaborative exercise was carried out among 38 forensic laboratories from 17 European countries. The results were assessed according to correct allele detection, peak heig…
The Physcomitrella genome reveals evolutionary insights into the conquest of land by plants
2008
We report the draft genome sequence of the model moss Physcomitrella patens and compare its features with those of flowering plants, from which it is separated by more than 400 million years, and unicellular aquatic algae. This comparison reveals genomic changes concomitant with the evolutionary movement to land, including a general increase in gene family complexity; loss of genes associated with aquatic environments (e.g., flagellar arms); acquisition of genes for tolerating terrestrial stresses (e.g., variation in temperature and water availability); and the development of the auxin and abscisic acid signaling pathways for coordinating multicellular growth and dehydration response. The …
Detection and organization of atrazine-degrading genetic potential of seventeen bacterial isolates belonging to divergent taxa indicate a recent comm…
2007
A collection of 17 atrazine-degrading bacteria isolated from soils was studied to determine the composition of the atrazine-degrading genetic potential (i.e. trzN, trzD and atz) and the presence of IS1071. The characterization of seven new atrazine-degrading bacteria revealed for the first time the trzN-atzBC gene composition in Gram-negative bacteria such as Sinorhizobium sp. or Polaromonas sp. Three main atrazine-degrading gene combinations (i) trzN– atzBC, (ii) atzABC– trzD and (iii) atzABCDEF were observed. The atz and trz genes were often located on plasmids, suggesting that plasmid conjugation could play an important role in their dispersion. In addition, the observation of these gene…