Search results for "serum protein"

showing 5 items of 15 documents

Discovery and Fine Mapping of Serum Protein Loci through Transethnic Meta-analysis

2012

Many disorders are associated with altered serum protein concentrations, including malnutrition, cancer, and cardiovascular, kidney, and inflammatory diseases. Although these protein concentrations are highly heritable, relatively little is known about their underlying genetic determinants. Through transethnic meta-analysis of European-ancestry and Japanese genome-wide association studies, we identified six loci at genome-wide significance (p −8 ) for serum albumin ( HPN-SCN1B , GCKR-FNDC4 , SERPINF2-WDR81 , TNFRSF11A-ZCCHC2 , FRMD5-WDR76 , and RPS11-FCGRT , in up to 53,190 European-ancestry and 9,380 Japanese individuals) and three loci for total protein ( TNFRS13B , 6q21.3, and ELL2 , in …

MaleLinkage disequilibriumGenome-wide association studyDETERMINANTSLinkage DisequilibriumMiceGenetics(clinical)POPULATIONGenetics (clinical)SNPSRISKGeneticseducation.field_of_studybiologyChromosome MappingBlood ProteinsIDENTIFYMiddle AgedFemaleAdultPopulationSerum albuminserum protein; albumin; GWASSingle-nucleotide polymorphismLocus (genetics)ALBUMINWhite PeopleAsian PeopleGene mappingSDG 3 - Good Health and Well-beingReportBIOCHEMICAL TRAITSFC-RECEPTORGeneticsAnimalsHumansGenetic Predisposition to DiseaseSMOKING-BEHAVIORddc:610GENOME-WIDE ASSOCIATIONeducationAllelesSerum AlbuminAgedGenetic associationGenetic LociProtein BiosynthesisProteolysisbiology.proteinRibosomesGenome-Wide Association StudyThe American Journal of Human Genetics
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Die Bedeutung des Serumeiweissbildes zur Diagnose vonBufo calamita Laur.,Bufo viridis Laur. und deren Bastarden (Amphibia, Anura, Bufonidae)

1973

Electrophoretic investigations of the serum protein patterns of natterjacks (Bufo calamita Laur.) from the Iberian Peninsula and from Western and Central Europe, and of green toads (Bufo viridis Laur.) from Central Europa, Asia Minor and North Africa show that the two species differ disctinctly in the position of their albumin fractions. The identification of problematic specimens can result from the production of mixed serum with specimens of both species. As the albumin fraction of hybrids is doubled according to this method, it is also suitable for demonstrating the existence of such hybrids in natural populations.

PharmacologyBufo viridisEcologySerum proteinZoologyNorth africaCell BiologyBiologybiology.organism_classificationCellular and Molecular NeuroscienceMolecular MedicineBufoMolecular BiologyHybridExperientia
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SPECIES-DEPENDENT STEREOSPECIFIC SERUM PROTEIN BINDING OF PHENPROCOUMON

1978

PhenprocoumonStereospecificityBiochemistryChemistrymedicineSerum proteinmedicine.drug
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Hp, Gc, Cp, Tf, Bg and Pi phenotypes in leprosy patients and healthy controls from West Bengal (India)

1972

On a sample of n=601 leprous individuals and n=386 healthy controls from West Bengal (India) the question is discussed, if there are existing any associations between leprosy and several serum protein groups like haptoglobin, Gc, ceruloplasmin, transferrin, β2 I and Pi. No associations were found concerning the haptoglobins and transferrins. Certain associations came out respecting ceruloplasmin, β2 I and Pi phenotypes. However, these associations, which were found in connection with the different types and clinical courses of leprosy, should be reexamined by further research. The most striking results were obtained concerning the Gc proteins. In accordance with previously performed investi…

Serum proteinIndiaGene FrequencyLeprosyGeneticsmedicineHumansMetabolic diseaseGenetics (clinical)Glycoproteinschemistry.chemical_classificationPolymorphism GeneticHaptoglobinsbiologyHaptoglobinTransferrinCeruloplasminPi phenotypesmedicine.diseasePhenotypechemistryTransferrinImmunologybiology.proteinSerum GlobulinsWest bengalLeprosyFactor Analysis StatisticalCeruloplasminHuman Genetics
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Honey Bee Pollen in Meagre (Argyrosomus regius) Juvenile Diets: Effects on Growth, Diet Digestibility, Intestinal Traits, and Biochemical Markers Rel…

2020

This research aimed to evaluate the effects of the inclusion of honey bee pollen (HBP) in meagre (Argyrosoumus regius) juveniles&rsquo

total serum proteingrowth trialtrace elementsArgyrosomus regiusmedicine.disease_causemeagre honey bee pollen growth trial digestibility trial TNF-α HSP70 intestinal immunohistochemistry toxic elements trace elements total serum proteinArticleintestinal immunohistochemistry03 medical and health sciencesAnimal sciencePredatory fishIntestinal mucosaSettore AGR/20 - ZoocolturePollenlcsh:Zoologymedicinelcsh:QL1-991toxic elementKeywords: meagreDigestibility trial; Growth trial; Honey bee pollen; HSP70; Intestinal immunohistochemistry; Meagre; TNF-α; Total serum protein; Toxic elements; Trace elementsHSP70030304 developmental biology2. Zero hungertoxic elements0303 health sciencesLamina proprialcsh:Veterinary medicineGeneral Veterinarybiologydigestibility trialfood and beveragestrace elementHistology04 agricultural and veterinary sciencesHoney beebiology.organism_classificationmeagre3. Good healthmedicine.anatomical_structureBee pollenTNF-α040102 fisherieslcsh:SF600-11000401 agriculture forestry and fisheriesAnimal Science and Zoologyhoney bee pollenAnimals
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